Molecular subtypes CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL nCNV (%) nWild-Type Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Amp Peak 1(1p34.2) 45 (30%) 105 0.00019969 0.0943 4.0864e-05 0.0199 0.89402 1 0.70601 1 0.014691 1 0.51983 1 0.075073 1 0.61609 1 Amp Peak 2(1q21.3) 76 (51%) 74 6.85e-06 0.00337 0.00039988 0.186 0.011755 1 0.051123 1 0.0037395 1 0.36547 1 0.061565 1 0.15524 1 Amp Peak 3(1q23.3) 82 (55%) 68 2.5929e-05 0.0127 0.012382 1 0.9254 1 0.58916 1 0.063352 1 0.71896 1 0.00017659 0.0837 0.0001443 0.0687 Amp Peak 4(3p25.2) 72 (48%) 78 3.3553e-05 0.0163 0.0016134 0.718 0.27822 1 0.03928 1 0.00084835 0.386 0.0003715 0.173 0.0018182 0.8 0.00024699 0.116 Amp Peak 5(3q26.32) 84 (56%) 66 0.0044027 1 0.66438 1 0.16067 1 0.81172 1 0.60054 1 0.87483 1 0.62375 1 0.26996 1 Amp Peak 6(4p16.3) 31 (21%) 119 0.017605 1 0.1717 1 0.16214 1 0.18857 1 0.10257 1 0.11838 1 0.03785 1 0.28619 1 Amp Peak 7(4q13.3) 23 (15%) 127 8.4547e-05 0.0406 0.15965 1 0.51704 1 0.86705 1 0.57148 1 0.39991 1 0.28835 1 0.27856 1 Amp Peak 8(5p15.1) 69 (46%) 81 4.4953e-05 0.0218 0.20229 1 0.013987 1 0.45966 1 0.094042 1 0.45769 1 0.076767 1 0.095368 1 Amp Peak 9(6p22.3) 61 (41%) 89 0.00018288 0.0865 0.0023585 1 0.83415 1 0.87182 1 0.55965 1 0.58141 1 0.094761 1 0.44878 1 Amp Peak 10(6q12) 25 (17%) 125 0.0060126 1 0.62748 1 1 1 1 1 1 1 0.66707 1 0.17865 1 0.0050674 1 Amp Peak 11(6q21) 18 (12%) 132 0.24512 1 0.05116 1 0.62114 1 0.58438 1 0.19838 1 0.15454 1 0.89801 1 1 1 Amp Peak 12(7p11.2) 78 (52%) 72 4.4909e-07 0.000224 0.0020026 0.875 0.48139 1 0.24295 1 0.82484 1 0.67802 1 0.75701 1 0.874 1 Amp Peak 13(8p11.23) 48 (32%) 102 0.00049153 0.227 0.048781 1 0.073189 1 0.016951 1 0.42305 1 0.27108 1 0.1589 1 0.51611 1 Amp Peak 14(8p11.21) 48 (32%) 102 1.6173e-05 0.00794 0.014559 1 0.59619 1 0.63731 1 0.26825 1 0.44823 1 0.032444 1 0.29751 1 Amp Peak 15(8q22.3) 92 (61%) 58 0.0040913 1 0.0020564 0.897 0.16764 1 0.20779 1 0.10839 1 0.43684 1 0.014568 1 0.19162 1 Amp Peak 16(8q24.21) 88 (59%) 62 0.0013776 0.616 0.021955 1 0.22617 1 0.35378 1 0.12541 1 0.19638 1 0.031083 1 0.37538 1 Amp Peak 17(10p15.1) 61 (41%) 89 6.729e-09 3.38e-06 5.2508e-06 0.00259 0.89314 1 0.21526 1 0.22073 1 0.058297 1 0.33645 1 0.10868 1 Amp Peak 18(11q13.3) 59 (39%) 91 0.0016929 0.748 0.23702 1 0.5536 1 0.5971 1 0.22237 1 0.31929 1 0.0013641 0.611 0.12359 1 Amp Peak 19(12q15) 48 (32%) 102 0.050913 1 0.10718 1 0.76019 1 0.43903 1 0.0081952 1 0.0021946 0.955 0.20237 1 0.28068 1 Amp Peak 20(13q22.1) 49 (33%) 101 0.58019 1 0.65884 1 0.64121 1 0.097132 1 0.88569 1 0.89845 1 0.45457 1 0.52144 1 Amp Peak 21(16p12.1) 39 (26%) 111 0.010368 1 0.11247 1 0.078326 1 0.4535 1 0.90043 1 0.84647 1 0.52636 1 0.79019 1 Amp Peak 22(17q11.2) 68 (45%) 82 4.6173e-08 2.31e-05 0.0012197 0.549 0.76019 1 0.43903 1 0.0001339 0.064 0.0031839 1 0.015216 1 0.018398 1 Amp Peak 23(17q12) 63 (42%) 87 0.0018998 0.834 0.15321 1 0.9394 1 0.43903 1 0.05045 1 0.25997 1 0.011225 1 0.068986 1 Amp Peak 24(19q12) 65 (43%) 85 6.3489e-06 0.00313 0.0027118 1 0.37007 1 0.93577 1 0.4558 1 0.43786 1 0.51759 1 0.28244 1 Amp Peak 25(19q13.43) 63 (42%) 87 9.0782e-05 0.0435 0.025791 1 0.77788 1 0.76681 1 0.081185 1 0.81907 1 0.20163 1 0.053695 1 Amp Peak 26(20q11.21) 104 (69%) 46 0.00069982 0.32 0.42783 1 0.34208 1 0.86458 1 0.20399 1 0.22575 1 0.27061 1 0.21809 1 Amp Peak 27(22q11.23) 35 (23%) 115 0.0013077 0.587 0.38329 1 0.83664 1 0.091558 1 0.14625 1 0.23153 1 0.27493 1 0.60143 1 Del Peak 1(1p36.11) 27 (18%) 123 0.96736 1 0.0049925 1 0.069891 1 0.011411 1 0.21564 1 0.18112 1 0.76383 1 0.032255 1 Del Peak 2(1q32.1) 28 (19%) 122 0.07233 1 0.11463 1 0.73836 1 0.37988 1 0.28241 1 0.11132 1 0.92799 1 0.68733 1 Del Peak 3(2q22.1) 43 (29%) 107 0.0031733 1 0.29465 1 0.3152 1 0.27846 1 0.57724 1 0.10238 1 0.17685 1 0.76026 1 Del Peak 4(2q34) 60 (40%) 90 3.5259e-06 0.00175 0.13729 1 0.3093 1 0.47215 1 0.15195 1 0.11116 1 0.11742 1 0.13694 1 Del Peak 5(2q37.1) 73 (49%) 77 3.2969e-05 0.0161 0.012785 1 0.90782 1 0.87528 1 0.06586 1 0.018377 1 0.06649 1 0.01643 1 Del Peak 6(3p21.31) 47 (31%) 103 0.00039436 0.184 0.12029 1 0.0064897 1 0.0023042 1 0.00055753 0.255 0.020288 1 0.082678 1 0.051222 1 Del Peak 7(3p14.2) 48 (32%) 102 0.000507 0.233 0.56029 1 0.075854 1 0.00029355 0.138 0.00042488 0.197 0.0075294 1 0.49804 1 0.15432 1 Del Peak 8(3p12.3) 41 (27%) 109 0.012731 1 0.45467 1 0.018856 1 0.00049489 0.228 0.0016441 0.728 0.052339 1 0.50778 1 0.18402 1 Del Peak 9(4q22.1) 59 (39%) 91 0.53909 1 0.62787 1 0.3577 1 1 1 0.2965 1 0.14893 1 0.95309 1 0.48926 1 Del Peak 10(4q34.2) 65 (43%) 85 0.065426 1 0.37403 1 0.42198 1 0.87528 1 0.52653 1 0.033339 1 0.073202 1 0.0083151 1 Del Peak 11(5q11.2) 75 (50%) 75 0.001051 0.475 0.051099 1 0.8138 1 0.47385 1 0.73893 1 0.090612 1 0.24765 1 0.028922 1 Del Peak 12(5q35.1) 72 (48%) 78 0.022817 1 0.0060952 1 0.56722 1 0.56809 1 0.60958 1 0.21445 1 0.10058 1 0.082631 1 Del Peak 13(6p25.3) 40 (27%) 110 0.020667 1 0.26872 1 0.13456 1 0.66031 1 0.51234 1 0.82396 1 0.38894 1 0.75609 1 Del Peak 14(6q21) 63 (42%) 87 7.2861e-07 0.000363 0.012898 1 0.079914 1 0.27212 1 0.31418 1 0.015304 1 0.47936 1 0.10109 1 Del Peak 15(6q27) 62 (41%) 88 2.0443e-06 0.00102 0.0023544 1 0.1565 1 0.34607 1 0.22073 1 0.0062481 1 0.18314 1 0.29174 1 Del Peak 16(8p23.3) 80 (53%) 70 2.103e-08 1.06e-05 5.2414e-05 0.0253 0.14489 1 0.38887 1 0.16869 1 0.96879 1 0.0058957 1 0.0093054 1 Del Peak 17(8p21.1) 84 (56%) 66 1.5307e-09 7.71e-07 5.1974e-05 0.0251 0.14489 1 0.38887 1 0.71307 1 0.49814 1 0.0018043 0.796 0.00074721 0.341 Del Peak 18(9p23) 65 (43%) 85 0.0019894 0.871 0.87362 1 0.27398 1 0.71654 1 0.46018 1 0.06327 1 0.4169 1 0.91457 1 Del Peak 19(9p21.3) 86 (57%) 64 0.0004823 0.223 0.56608 1 0.071796 1 0.93048 1 0.25138 1 0.12762 1 0.75182 1 0.52534 1 Del Peak 20(10p12.1) 29 (19%) 121 0.90997 1 0.76928 1 0.45485 1 0.90556 1 0.068631 1 0.02926 1 0.2333 1 0.045086 1 Del Peak 21(10q23.31) 60 (40%) 90 0.010543 1 0.0025019 1 0.2284 1 0.92873 1 0.27708 1 0.045653 1 0.45274 1 0.10868 1 Del Peak 22(11p15.5) 73 (49%) 77 5.1247e-06 0.00254 0.037959 1 0.19518 1 0.6729 1 0.12502 1 0.00015223 0.0723 0.00164 0.728 0.01643 1 Del Peak 23(11q25) 47 (31%) 103 4.2645e-05 0.0207 0.33748 1 0.37822 1 1 1 0.19997 1 0.54929 1 0.11236 1 0.058781 1 Del Peak 24(13q14.2) 58 (39%) 92 0.00013481 0.0643 0.98586 1 0.00022903 0.108 0.0087455 1 0.092842 1 0.23523 1 0.9062 1 0.68684 1 Del Peak 25(14q12) 43 (29%) 107 0.0008936 0.406 0.00094091 0.426 0.8053 1 0.59817 1 0.14201 1 0.034159 1 0.12475 1 0.097877 1 Del Peak 26(14q32.31) 41 (27%) 109 5.9484e-05 0.0286 0.027201 1 0.8053 1 0.84344 1 0.21839 1 0.24745 1 0.00050295 0.231 0.0013936 0.622 Del Peak 27(15q13.1) 54 (36%) 96 0.00030099 0.141 0.0031238 1 0.082907 1 0.45966 1 0.5797 1 0.78021 1 0.084223 1 0.028272 1 Del Peak 28(16p13.3) 54 (36%) 96 0.0033236 1 0.0065187 1 0.19141 1 0.22993 1 1 1 0.49891 1 0.5912 1 0.37685 1 Del Peak 29(16q23.1) 38 (25%) 112 1.9895e-05 0.00975 0.043382 1 0.23182 1 0.7533 1 0.61133 1 0.95968 1 0.077252 1 0.080066 1 Del Peak 30(17p12) 77 (51%) 73 2.9136e-08 1.46e-05 0.017517 1 0.55568 1 0.40504 1 0.021805 1 0.02453 1 0.22497 1 0.52818 1 Del Peak 31(18q23) 63 (42%) 87 0.0037721 1 0.48466 1 0.97864 1 0.76299 1 0.84611 1 0.37044 1 0.019365 1 0.0027826 1 Del Peak 32(19p13.3) 60 (40%) 90 0.022727 1 0.026551 1 1 1 0.75741 1 0.9439 1 0.083106 1 0.42794 1 0.21547 1 Del Peak 33(22q13.32) 60 (40%) 90 0.0011155 0.503 0.25987 1 0.12831 1 0.067522 1 0.106 1 0.11469 1 0.6789 1 0.21547 1 Del Peak 34(Xp11.3) 39 (26%) 111 0.19953 1 0.0029406 1 0.77519 1 0.92232 1 0.076659 1 0.23561 1 0.40702 1 0.94284 1 Del Peak 35(Xq21.33) 35 (23%) 115 0.33434 1 0.078904 1 0.17296 1 0.17311 1 0.0091947 1 0.73532 1 0.1974 1 0.24851 1 Del Peak 36(Xq22.3) 32 (21%) 118 0.13645 1 0.017277 1 0.14922 1 0.52004 1 0.017407 1 0.79604 1 0.091401 1 0.27669 1