Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.038 0.136 0.393 14.0 -9999.0 0.0 14.0 KIRREL -0.03 0.155 -9999.0 0.0 -0.65 7.0 7.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.038 0.137 -9999.0 0.0 -0.394 14.0 14.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.054 0.133 -9999.0 0.0 -0.421 12.0 12.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.017 0.111 -9999.0 0.0 -0.334 12.0 12.0 FYN -0.036 0.131 -9999.0 0.0 -0.399 12.0 12.0 mol:Ca2+ -0.053 0.132 -9999.0 0.0 -0.417 12.0 12.0 mol:DAG -0.053 0.132 -9999.0 0.0 -0.419 12.0 12.0 NPHS2 -0.043 0.16 -9999.0 0.0 -0.589 9.0 9.0 mol:IP3 -0.053 0.132 -9999.0 0.0 -0.419 12.0 12.0 regulation of endocytosis -0.027 0.124 -9999.0 0.0 -0.37 12.0 12.0 Nephrin/NEPH1/podocin/Cholesterol -0.052 0.137 -9999.0 0.0 -0.428 12.0 12.0 establishment of cell polarity -0.038 0.136 -9999.0 0.0 -0.393 14.0 14.0 Nephrin/NEPH1/podocin/NCK1-2 -0.025 0.13 -9999.0 0.0 -0.382 12.0 12.0 Nephrin/NEPH1/beta Arrestin2 -0.027 0.125 -9999.0 0.0 -0.375 12.0 12.0 NPHS1 -0.027 0.1 -9999.0 0.0 -0.395 8.0 8.0 Nephrin/NEPH1/podocin -0.037 0.131 -9999.0 0.0 -0.401 12.0 12.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.054 0.133 -9999.0 0.0 -0.421 12.0 12.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.054 0.133 -9999.0 0.0 -0.421 12.0 12.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.034 0.129 -9999.0 0.0 -0.386 12.0 12.0 cytoskeleton organization -0.019 0.133 -9999.0 0.0 -0.397 12.0 12.0 Nephrin/NEPH1 -0.025 0.099 -9999.0 0.0 -0.363 8.0 8.0 Nephrin/NEPH1/ZO-1 -0.037 0.105 -9999.0 0.0 -0.42 7.0 7.0