Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.019 0.197 -9999.0 0.0 -0.559 10.0 10.0 MAP3K8 0.001 0.088 -9999.0 0.0 -0.68 2.0 2.0 FOS -0.025 0.188 -9999.0 0.0 -0.617 8.0 8.0 PRKCA 0.007 0.062 -9999.0 0.0 -0.679 1.0 1.0 PTPN7 -0.042 0.175 -9999.0 0.0 -0.554 12.0 12.0 HRAS 0.012 0.001 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.063 0.203 -9999.0 0.0 -0.567 16.0 16.0 NRAS 0.012 0.001 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.023 0.021 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.023 0.165 -9999.0 0.0 -0.56 8.0 8.0 MAP2K1 -0.018 0.171 -9999.0 0.0 -0.543 10.0 10.0 ELK1 0.013 0.003 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.024 0.162 -9999.0 0.0 -0.523 10.0 10.0 mol:GTP 0.0 0.001 -9999.0 0.0 -0.004 4.0 4.0 MAPK1 -0.023 0.165 -9999.0 0.0 -0.56 8.0 8.0 RAF1 -0.025 0.162 -9999.0 0.0 -0.523 10.0 10.0 KRAS 0.009 0.036 -9999.0 0.0 -0.387 1.0 1.0