Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.038	0.223	0.427	4.0	-0.653	82.0	86.0
IHH	0.017	0.081	0.289	6.0	-0.246	1.0	7.0
SHH Np/Cholesterol/GAS1	-0.001	0.081	-9999.0	0.0	-0.351	39.0	39.0
LRPAP1	0.024	0.005	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.001	0.08	0.349	39.0	-9999.0	0.0	39.0
SMO/beta Arrestin2	-0.015	0.204	-9999.0	0.0	-0.636	66.0	66.0
SMO	-0.039	0.206	-9999.0	0.0	-0.666	67.0	67.0
AKT1	0.0	0.124	-9999.0	0.0	-0.577	16.0	16.0
ARRB2	0.022	0.007	-9999.0	0.0	-9999.0	0.0	0.0
BOC	-0.02	0.16	-9999.0	0.0	-0.601	58.0	58.0
ADRBK1	0.023	0.007	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.038	0.202	-9999.0	0.0	-0.653	67.0	67.0
STIL	0.013	0.175	0.304	26.0	-0.505	59.0	85.0
DHH N/PTCH2	-0.017	0.156	-9999.0	0.0	-0.466	86.0	86.0
DHH N/PTCH1	-0.023	0.201	-9999.0	0.0	-0.556	87.0	87.0
PIK3CA	0.024	0.005	-9999.0	0.0	-9999.0	0.0	0.0
DHH	0.008	0.101	0.267	1.0	-0.601	22.0	23.0
PTHLH	-0.055	0.291	0.44	10.0	-0.842	85.0	95.0
determination of left/right symmetry	-0.038	0.202	-9999.0	0.0	-0.653	67.0	67.0
PIK3R1	0.024	0.005	-9999.0	0.0	-9999.0	0.0	0.0
skeletal system development	-0.054	0.287	0.439	10.0	-0.829	85.0	95.0
IHH N/Hhip	0.029	0.056	-9999.0	0.0	-0.489	1.0	1.0
DHH N/Hhip	0.023	0.081	-9999.0	0.0	-0.442	23.0	23.0
mol:Cholesterol	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.038	0.202	-9999.0	0.0	-0.653	67.0	67.0
pancreas development	0.024	0.031	0.266	7.0	-0.6	1.0	8.0
HHAT	0.02	0.023	-9999.0	0.0	-0.601	1.0	1.0
PI3K	0.034	0.01	-9999.0	0.0	-9999.0	0.0	0.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.009	0.14	-9999.0	0.0	-0.601	44.0	44.0
somite specification	-0.038	0.202	-9999.0	0.0	-0.653	67.0	67.0
SHH Np/Cholesterol/PTCH1	-0.022	0.158	0.284	2.0	-0.511	65.0	67.0
SHH Np/Cholesterol/PTCH2	-0.011	0.097	-9999.0	0.0	-0.354	56.0	56.0
SHH Np/Cholesterol/Megalin	-0.064	0.156	0.284	3.0	-0.355	170.0	173.0
SHH	-0.002	0.037	0.356	4.0	-0.453	1.0	5.0
catabolic process	-0.028	0.202	0.353	1.0	-0.578	86.0	87.0
SMO/Vitamin D3	-0.005	0.196	0.37	12.0	-0.591	62.0	74.0
SHH Np/Cholesterol/Hhip	0.016	0.033	0.287	5.0	-0.359	2.0	7.0
LRP2	-0.126	0.276	0.267	20.0	-0.601	206.0	226.0
receptor-mediated endocytosis	-0.078	0.222	0.308	8.0	-0.644	72.0	80.0
SHH Np/Cholesterol/BOC	-0.006	0.091	-9999.0	0.0	-0.353	49.0	49.0
SHH Np/Cholesterol/CDO	0.012	0.042	-9999.0	0.0	-0.356	9.0	9.0
mesenchymal cell differentiation	-0.016	0.033	0.357	2.0	-0.285	5.0	7.0
mol:Vitamin D3	0.006	0.181	0.349	17.0	-0.517	64.0	81.0
IHH N/PTCH2	-0.014	0.154	-9999.0	0.0	-0.49	71.0	71.0
CDON	0.015	0.065	-9999.0	0.0	-0.601	9.0	9.0
IHH N/PTCH1	-0.019	0.208	0.359	3.0	-0.582	86.0	89.0
Megalin/LRPAP1	-0.083	0.212	-9999.0	0.0	-0.444	209.0	209.0
PTCH2	-0.028	0.173	-9999.0	0.0	-0.601	69.0	69.0
SHH Np/Cholesterol	0.01	0.015	-9999.0	0.0	-0.355	1.0	1.0
PTCH1	-0.028	0.203	0.354	1.0	-0.581	86.0	87.0
HHIP	0.024	0.032	0.267	7.0	-0.601	1.0	8.0