Molecular subtypes CN_CNMF METHLYATION_CNMF MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Amp Peak 1(1q21.3) 67 (53%) 59 0.010299 1 0.098011 1 0.3859 1 0.63478 1 0.58034 1 0.56573 1 Amp Peak 2(1q44) 68 (54%) 58 0.0090513 1 0.7855 1 0.57298 1 1 1 0.20975 1 0.5463 1 Amp Peak 3(2p24.3) 33 (26%) 93 0.14732 1 0.50456 1 0.060541 1 0.068937 1 0.086885 1 0.0056044 1 Amp Peak 4(2q32.3) 20 (16%) 106 0.00023823 0.0715 0.081746 1 0.00064472 0.193 0.0061458 1 0.79469 1 0.018513 1 Amp Peak 5(3q26.2) 95 (75%) 31 1.2588e-06 0.000391 0.58524 1 0.093139 1 0.33229 1 0.84959 1 0.10529 1 Amp Peak 6(3q28) 94 (75%) 32 6.3662e-07 0.000199 0.70238 1 0.049248 1 0.36347 1 0.8181 1 0.062998 1 Amp Peak 7(4q12) 12 (10%) 114 0.50694 1 0.16538 1 0.08257 1 0.0043607 1 0.21598 1 0.020828 1 Amp Peak 8(6p21.33) 35 (28%) 91 0.0049459 1 0.008632 1 0.0028566 0.82 0.055283 1 0.18249 1 0.031924 1 Amp Peak 9(6q12) 24 (19%) 102 0.34239 1 0.13487 1 0.14331 1 0.0085782 1 0.2386 1 0.18147 1 Amp Peak 10(8q24.21) 53 (42%) 73 0.0020677 0.6 0.84904 1 0.64722 1 0.5345 1 0.089099 1 0.49105 1 Amp Peak 11(8q24.21) 48 (38%) 78 0.0043206 1 0.28698 1 0.70467 1 0.38597 1 0.33956 1 0.85218 1 Amp Peak 12(9p24.1) 28 (22%) 98 0.058746 1 0.58581 1 0.80572 1 0.52752 1 0.23351 1 0.68528 1 Amp Peak 13(11q13.3) 18 (14%) 108 0.038427 1 0.72637 1 0.017077 1 0.029055 1 0.10718 1 0.88524 1 Amp Peak 14(11q22.1) 27 (21%) 99 7.3834e-05 0.0225 0.072349 1 0.078156 1 0.22307 1 0.013247 1 0.12332 1 Amp Peak 15(13q22.1) 27 (21%) 99 0.0053383 1 0.38656 1 0.20498 1 0.22416 1 0.16226 1 0.019537 1 Amp Peak 16(14q24.1) 25 (20%) 101 0.68921 1 0.78032 1 0.28249 1 0.11306 1 0.70535 1 0.95534 1 Amp Peak 17(15q26.3) 30 (24%) 96 0.0058351 1 0.44713 1 0.31633 1 0.53936 1 0.92776 1 1 1 Amp Peak 18(16p13.2) 27 (21%) 99 0.075677 1 0.20128 1 0.87008 1 0.73882 1 0.77946 1 0.80611 1 Amp Peak 19(16p13.13) 30 (24%) 96 0.061791 1 0.13945 1 0.6472 1 0.23496 1 0.68238 1 0.46536 1 Amp Peak 20(17q12) 21 (17%) 105 0.063094 1 0.051602 1 0.012578 1 0.095149 1 0.11156 1 0.065029 1 Amp Peak 21(17q25.1) 34 (27%) 92 0.011254 1 0.043009 1 0.041117 1 0.429 1 0.47976 1 0.60713 1 Amp Peak 22(19q13.31) 43 (34%) 83 0.012391 1 0.64191 1 0.28739 1 0.15429 1 0.099471 1 0.87442 1 Amp Peak 23(20q11.21) 61 (48%) 65 0.0009981 0.295 0.37146 1 0.2829 1 0.25567 1 0.53201 1 0.72184 1 Amp Peak 24(Xq28) 36 (29%) 90 0.79479 1 0.13874 1 0.67264 1 0.90893 1 0.043333 1 0.13264 1 Del Peak 1(1p36.23) 20 (16%) 106 0.082886 1 0.032895 1 0.0012472 0.365 0.0012989 0.379 0.47387 1 0.00020265 0.0612 Del Peak 2(1p13.1) 12 (10%) 114 0.74963 1 0.37536 1 1 1 1 1 0.31583 1 0.91866 1 Del Peak 3(2q22.1) 22 (17%) 104 0.05246 1 0.63268 1 0.90643 1 0.8212 1 0.91058 1 0.95253 1 Del Peak 4(2q37.1) 51 (40%) 75 0.004309 1 0.03674 1 0.20053 1 0.33312 1 0.17181 1 0.07656 1 Del Peak 5(3p11.1) 51 (40%) 75 0.00066847 0.199 0.027172 1 0.39013 1 0.0023225 0.669 0.12906 1 0.0070629 1 Del Peak 6(4q22.1) 39 (31%) 87 1.4978e-06 0.000464 0.061649 1 0.072253 1 0.53389 1 0.19961 1 0.29656 1 Del Peak 7(4q35.2) 47 (37%) 79 1.3808e-05 0.00427 0.032342 1 0.049923 1 0.16024 1 0.57485 1 0.32327 1 Del Peak 8(5q14.3) 36 (29%) 90 0.02446 1 0.17428 1 0.63097 1 0.14402 1 0.21556 1 0.34619 1 Del Peak 9(6p24.3) 18 (14%) 108 0.61898 1 0.19169 1 0.25841 1 0.15863 1 0.4994 1 1 1 Del Peak 10(6p12.1) 20 (16%) 106 0.67376 1 0.50249 1 0.46642 1 0.12304 1 0.81894 1 0.1346 1 Del Peak 11(6q26) 48 (38%) 78 0.13351 1 0.33038 1 0.36286 1 0.67594 1 0.5447 1 0.49496 1 Del Peak 12(7q34) 28 (22%) 98 0.0052657 1 0.86016 1 0.12004 1 0.66785 1 0.06827 1 0.19763 1 Del Peak 13(10q23.31) 39 (31%) 87 0.022125 1 0.66782 1 0.27249 1 0.019662 1 0.7391 1 0.86992 1 Del Peak 14(10q26.3) 38 (30%) 88 0.00013319 0.0405 0.51596 1 0.42107 1 0.39785 1 0.70753 1 0.77655 1 Del Peak 15(11p15.1) 40 (32%) 86 0.30056 1 0.08751 1 0.16168 1 0.066465 1 0.3509 1 0.50167 1 Del Peak 16(11q25) 74 (59%) 52 0.002231 0.645 0.14855 1 0.12726 1 0.10576 1 0.026739 1 0.44663 1 Del Peak 17(13q13.3) 52 (41%) 74 0.14388 1 0.091646 1 0.39763 1 0.8072 1 0.019671 1 0.10669 1 Del Peak 18(14q32.31) 25 (20%) 101 0.077353 1 0.008392 1 0.0011751 0.347 0.0012213 0.359 0.023958 1 0.0051992 1 Del Peak 19(15q15.1) 29 (23%) 97 2.6783e-05 0.00825 0.34646 1 0.30326 1 0.29167 1 0.17641 1 0.086884 1 Del Peak 20(16q11.2) 25 (20%) 101 0.74968 1 0.03625 1 0.010279 1 0.0081198 1 0.13908 1 0.0018819 0.548 Del Peak 21(16q23.1) 28 (22%) 98 1 1 0.020248 1 0.0002345 0.0706 3.4544e-05 0.0106 0.14254 1 0.00019738 0.0598 Del Peak 22(17p12) 42 (33%) 84 0.011057 1 0.13588 1 0.23336 1 0.75548 1 0.093152 1 0.043952 1 Del Peak 23(17q25.3) 22 (17%) 104 0.045076 1 0.00090681 0.269 0.035891 1 0.034512 1 0.048371 1 0.042595 1 Del Peak 24(19p13.3) 39 (31%) 87 0.0030231 0.862 1 1 0.0029499 0.844 0.069879 1 0.031766 1 3.5431e-05 0.0108 Del Peak 25(20p12.1) 17 (13%) 109 0.84591 1 0.34233 1 0.7457 1 1 1 0.43372 1 0.45101 1 Del Peak 26(21q21.1) 27 (21%) 99 0.061792 1 0.37215 1 0.56909 1 0.38658 1 0.5265 1 0.80046 1 Del Peak 27(Xp11.3) 37 (29%) 89 0.0044095 1 0.0042447 1 0.21082 1 0.19198 1 0.011857 1 0.0037528 1 Del Peak 28(Xq21.33) 27 (21%) 99 0.011901 1 0.0044384 1 0.16396 1 0.090148 1 0.10126 1 0.0095519 1