Molecular subtypes MRNA_CNMF MRNA_CHIERARCHICAL CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Amp Peak 1(2q33.1) 79 (19%) 334 0.073363 1 0.10484 1 3.054e-05 0.0174 0.25825 1 0.31656 1 0.01389 1 0.0005156 0.271 0.013678 1 0.27725 1 0.25803 1 Amp Peak 2(5p13.2) 81 (20%) 332 0.33423 1 0.46916 1 0.00020181 0.109 0.14972 1 0.39333 1 0.54293 1 0.086386 1 0.069637 1 0.9268 1 0.58108 1 Amp Peak 3(5q22.3) 40 (10%) 373 0.78032 1 0.629 1 0.029319 1 0.87467 1 0.031738 1 0.73476 1 0.16547 1 0.11152 1 0.69302 1 0.83892 1 Amp Peak 4(6p21.1) 89 (22%) 324 0.09021 1 0.00099634 0.503 3.3666e-09 2.06e-06 0.16999 1 0.60956 1 0.019508 1 0.0064373 1 0.033042 1 0.77582 1 0.25832 1 Amp Peak 5(8p11.23) 144 (35%) 269 0.44402 1 0.23056 1 2.9884e-13 1.94e-10 0.8676 1 0.53191 1 0.44625 1 0.21112 1 0.78274 1 0.17898 1 0.18914 1 Amp Peak 6(8p11.21) 173 (42%) 240 0.35459 1 0.12919 1 4.5091e-10 2.8e-07 0.88585 1 0.31387 1 0.033841 1 0.42103 1 0.60595 1 0.50206 1 0.21775 1 Amp Peak 7(8q12.1) 215 (52%) 198 0.15037 1 0.064623 1 9.3098e-12 5.92e-09 0.038349 1 0.15278 1 0.0033592 1 0.014129 1 0.22829 1 0.12567 1 0.29537 1 Amp Peak 8(8q24.21) 239 (58%) 174 0.20284 1 0.10723 1 7.8615e-14 5.13e-11 0.010196 1 0.2937 1 0.018859 1 0.0063634 1 0.44468 1 0.4037 1 0.21493 1 Amp Peak 9(11p15.5) 86 (21%) 327 1.3774e-05 0.00793 0.00020098 0.109 1.539e-09 9.48e-07 0.00061244 0.318 0.083593 1 0.0010927 0.549 0.001929 0.951 0.0084545 1 0.11742 1 0.20078 1 Amp Peak 10(12p13.33) 104 (25%) 309 0.46331 1 0.88218 1 0.06118 1 0.24692 1 0.52123 1 0.70169 1 0.33441 1 0.97693 1 0.30362 1 0.17308 1 Amp Peak 11(13q12.13) 250 (61%) 163 7.2138e-08 4.31e-05 5.2734e-06 0.00306 5.0359e-36 3.39e-33 0.00027008 0.145 0.23778 1 0.0067255 1 1.2693e-06 0.000745 0.00019564 0.106 0.45926 1 0.79848 1 Amp Peak 12(13q22.1) 254 (62%) 159 6.3426e-05 0.0356 5.4308e-05 0.0306 7.1998e-33 4.83e-30 0.00051007 0.269 0.34516 1 0.0089053 1 1.1465e-06 0.000674 7.6662e-05 0.0427 0.2718 1 0.97749 1 Amp Peak 13(16p11.2) 116 (28%) 297 0.00044664 0.236 0.00037543 0.2 8.5536e-19 5.67e-16 0.021155 1 0.097692 1 0.0013022 0.646 0.00042856 0.228 0.0083752 1 0.77077 1 0.80885 1 Amp Peak 14(16q12.1) 102 (25%) 311 3.0222e-05 0.0173 0.00012608 0.0692 1.6709e-20 1.11e-17 0.05111 1 0.41059 1 0.0081542 1 0.000642 0.333 0.0025448 1 0.90192 1 0.93019 1 Amp Peak 15(17q12) 101 (24%) 312 0.098898 1 0.085195 1 7.529e-07 0.000443 0.016408 1 0.70991 1 0.00025435 0.137 4.5905e-05 0.0259 0.014164 1 0.012101 1 0.98573 1 Amp Peak 16(17q24.1) 92 (22%) 321 0.051891 1 0.008206 1 1.6072e-08 9.69e-06 0.012293 1 0.50039 1 0.00091661 0.465 6.0366e-06 0.0035 0.0031161 1 0.0025416 1 0.78116 1 Amp Peak 17(19p13.2) 65 (16%) 348 0.053531 1 0.034546 1 4.8203e-05 0.0272 0.28305 1 0.90658 1 0.59622 1 0.50145 1 0.53917 1 0.20371 1 0.38494 1 Amp Peak 18(19q13.11) 83 (20%) 330 0.33237 1 0.017695 1 0.0019963 0.98 0.51687 1 0.26117 1 0.84144 1 0.073608 1 0.16703 1 0.41715 1 0.49068 1 Amp Peak 19(20p12.3) 184 (45%) 229 0.001879 0.928 0.00084421 0.43 1.8596e-12 1.2e-09 0.4343 1 0.042122 1 0.32421 1 0.030504 1 0.0097172 1 0.59687 1 0.19482 1 Amp Peak 20(20p11.23) 205 (50%) 208 0.026709 1 0.00079247 0.406 1.2622e-16 8.32e-14 0.10514 1 0.27181 1 0.23567 1 0.00051306 0.27 0.0010395 0.524 0.45496 1 0.2118 1 Amp Peak 21(20p11.21) 230 (56%) 183 0.00069189 0.357 4.2653e-05 0.0242 4.0003e-23 2.67e-20 0.0011341 0.568 0.24401 1 0.04663 1 2.4063e-07 0.000143 1.3852e-06 0.000812 0.17441 1 0.50927 1 Amp Peak 22(20q11.21) 296 (72%) 117 1.0709e-10 6.69e-08 2.8619e-11 1.8e-08 1.5358e-43 1.04e-40 2.1904e-09 1.34e-06 0.039267 1 0.00023238 0.126 1.4664e-14 9.62e-12 3.8499e-12 2.47e-09 0.44287 1 1 1 Amp Peak 23(20q12) 297 (72%) 116 9.2845e-12 5.91e-09 1.8183e-11 1.15e-08 6.2847e-43 4.24e-40 1.5835e-08 9.58e-06 0.008137 1 0.00016739 0.0912 5.477e-14 3.59e-11 1.3447e-11 8.53e-09 0.40581 1 0.94846 1 Amp Peak 24(20q13.32) 300 (73%) 113 2.8741e-10 1.79e-07 6.2668e-12 4e-09 3.1794e-43 2.15e-40 1.5835e-08 9.58e-06 0.010986 1 0.00011898 0.0654 5.477e-14 3.59e-11 1.3447e-11 8.53e-09 0.414 1 0.96035 1 Del Peak 1(1p36.11) 150 (36%) 263 6.8119e-05 0.0382 0.0057606 1 6.3163e-17 4.17e-14 0.00079247 0.406 0.028058 1 0.0020014 0.981 0.0003474 0.186 0.0012029 0.599 0.4086 1 0.06244 1 Del Peak 2(1p33) 107 (26%) 306 0.02462 1 0.53242 1 1.0878e-11 6.91e-09 0.0066849 1 0.10594 1 0.035644 1 0.0050982 1 0.014081 1 0.8934 1 0.051913 1 Del Peak 3(1p13.1) 103 (25%) 310 0.11505 1 0.37439 1 6.8461e-10 4.25e-07 0.18487 1 0.30835 1 0.15513 1 0.083567 1 0.00481 1 0.86754 1 0.37862 1 Del Peak 4(1q43) 44 (11%) 369 0.098319 1 0.45814 1 6.9784e-06 0.00404 0.10478 1 0.49989 1 0.68967 1 0.031175 1 0.011378 1 0.33504 1 0.30091 1 Del Peak 5(2q37.2) 21 (5%) 392 0.92768 1 0.059766 1 0.97728 1 0.70132 1 0.044596 1 0.76813 1 1 1 0.18364 1 0.44659 1 0.44658 1 Del Peak 6(3p26.1) 60 (15%) 353 0.099398 1 0.30369 1 0.00043027 0.228 0.26787 1 0.88619 1 0.46377 1 0.53918 1 0.088268 1 0.5406 1 0.9578 1 Del Peak 7(3p14.2) 75 (18%) 338 0.46592 1 0.74447 1 0.2053 1 0.73514 1 0.95891 1 0.48273 1 0.63238 1 0.48277 1 0.20335 1 0.53643 1 Del Peak 8(3q26.31) 39 (9%) 374 0.12215 1 0.60527 1 0.0081756 1 0.49692 1 0.089676 1 0.38482 1 0.45817 1 0.022264 1 0.14968 1 0.93943 1 Del Peak 9(4p16.2) 121 (29%) 292 0.0019405 0.955 0.010727 1 1.1565e-12 7.47e-10 0.011034 1 0.18206 1 0.063983 1 0.0002371 0.128 0.00010675 0.059 0.37622 1 0.20636 1 Del Peak 10(4q22.1) 126 (31%) 287 0.00058503 0.306 0.0086401 1 8.4971e-12 5.42e-09 0.0020663 1 0.34086 1 0.14663 1 9.2324e-05 0.0512 2.8143e-05 0.0161 0.20975 1 0.51791 1 Del Peak 11(4q35.1) 137 (33%) 276 0.00012764 0.0699 0.0092819 1 1.0461e-13 6.82e-11 7.6854e-05 0.0427 0.24211 1 0.18155 1 0.00023919 0.129 0.00052743 0.276 0.41578 1 0.23487 1 Del Peak 12(5q11.2) 91 (22%) 322 0.001293 0.643 0.0037754 1 4.9424e-09 3.01e-06 0.03386 1 0.52788 1 0.016896 1 0.0014217 0.704 0.0078063 1 0.83478 1 0.21521 1 Del Peak 13(5q21.3) 117 (28%) 296 0.11805 1 0.028088 1 1.1415e-09 7.04e-07 0.035903 1 0.19902 1 0.055601 1 0.0043777 1 0.01043 1 0.65358 1 0.36044 1 Del Peak 14(5q23.1) 107 (26%) 306 0.062839 1 0.035574 1 1.5714e-08 9.52e-06 0.087019 1 0.18276 1 0.081973 1 0.021902 1 0.012593 1 0.62161 1 0.24578 1 Del Peak 15(6p25.3) 54 (13%) 359 0.97109 1 0.79153 1 0.00010249 0.0568 0.052651 1 0.71434 1 0.46846 1 0.35329 1 0.788 1 0.40629 1 0.45348 1 Del Peak 16(6q26) 60 (15%) 353 0.38305 1 0.30369 1 0.15693 1 0.35648 1 0.14683 1 0.66744 1 0.87302 1 0.69718 1 0.79664 1 0.52977 1 Del Peak 17(7q31.1) 11 (3%) 402 1 1 0.50413 1 0.81645 1 0.79545 1 0.32235 1 0.43926 1 0.49001 1 1 1 1 1 0.56392 1 Del Peak 18(8p23.3) 171 (41%) 242 0.0027614 1 0.00060268 0.315 6.8386e-26 4.58e-23 3.6131e-06 0.0021 0.20677 1 0.00024328 0.131 0.00067246 0.348 0.0023104 1 0.1544 1 0.84763 1 Del Peak 19(8p22) 185 (45%) 228 0.0011512 0.576 0.00095796 0.485 2.4052e-30 1.61e-27 3.4605e-07 0.000205 0.13347 1 1.2813e-05 0.00739 2.1632e-05 0.0124 0.00065641 0.34 0.11474 1 0.83207 1 Del Peak 20(8p11.22) 80 (19%) 333 0.21341 1 0.11826 1 8.8799e-09 5.4e-06 0.061445 1 0.017787 1 0.039351 1 0.099284 1 0.080437 1 0.35945 1 0.8314 1 Del Peak 21(8p11.21) 43 (10%) 370 0.023081 1 0.3509 1 5.8112e-07 0.000343 0.36576 1 0.28608 1 0.067672 1 0.48334 1 0.30826 1 0.099704 1 0.54888 1 Del Peak 22(9p21.3) 56 (14%) 357 0.25087 1 0.26423 1 4.5111e-05 0.0256 0.20379 1 0.80802 1 0.14978 1 0.063689 1 0.12685 1 0.90376 1 0.66315 1 Del Peak 23(10p15.3) 68 (16%) 345 0.2615 1 0.14131 1 2.2472e-08 1.35e-05 0.029141 1 0.33083 1 0.051944 1 0.12642 1 0.033979 1 0.67983 1 0.56551 1 Del Peak 24(10q21.1) 82 (20%) 331 0.0092802 1 0.037387 1 2.2397e-11 1.41e-08 0.19404 1 0.6001 1 0.0047147 1 0.19132 1 0.043135 1 0.8868 1 0.8314 1 Del Peak 25(10q23.31) 94 (23%) 319 0.24899 1 0.082921 1 3.4604e-07 0.000205 0.08012 1 0.52789 1 0.21357 1 0.034832 1 0.16507 1 0.8849 1 0.98489 1 Del Peak 26(10q25.2) 93 (23%) 320 0.17166 1 0.010498 1 1.9136e-11 1.21e-08 0.013884 1 0.14806 1 0.20467 1 0.0031176 1 0.0025038 1 0.92109 1 0.5932 1 Del Peak 27(12p13.2) 44 (11%) 369 0.040366 1 0.0079614 1 9.8715e-08 5.89e-05 0.20712 1 0.45186 1 0.82607 1 0.026163 1 0.0036908 1 0.69486 1 0.97344 1 Del Peak 28(13q14.13) 18 (4%) 395 0.39468 1 0.87562 1 0.00012763 0.0699 0.15251 1 0.65407 1 0.12661 1 0.22843 1 0.45153 1 0.61393 1 0.83372 1 Del Peak 29(14q32.11) 133 (32%) 280 2.1229e-05 0.0122 0.00011007 0.0608 1.6095e-20 1.07e-17 0.00070714 0.364 0.00060777 0.317 0.0011958 0.597 7.3029e-05 0.0408 0.00084042 0.429 0.31936 1 0.061222 1 Del Peak 30(15q11.2) 160 (39%) 253 0.00042205 0.225 0.0068286 1 1.1969e-21 7.98e-19 0.0043207 1 0.036727 1 0.059791 1 2.0921e-06 0.00122 0.00011707 0.0645 0.87692 1 0.8927 1 Del Peak 31(15q21.1) 151 (37%) 262 0.012982 1 0.041108 1 8.1471e-18 5.39e-15 0.0074658 1 0.063854 1 0.039485 1 2.0274e-07 0.000121 2.0517e-05 0.0118 0.9795 1 0.62069 1 Del Peak 32(15q22.33) 145 (35%) 268 0.00075795 0.389 0.0032684 1 2.4843e-21 1.65e-18 0.00043461 0.23 0.15245 1 0.033043 1 3.0692e-08 1.84e-05 7.5506e-06 0.00436 0.94865 1 0.3645 1 Del Peak 33(16p13.3) 45 (11%) 368 0.33381 1 0.15535 1 0.20817 1 0.37632 1 0.17412 1 0.92247 1 0.61959 1 0.57186 1 0.84166 1 0.73884 1 Del Peak 34(16q23.1) 49 (12%) 364 0.25945 1 0.0078488 1 0.13094 1 0.33681 1 0.62963 1 0.72583 1 0.042079 1 0.070054 1 0.97682 1 0.50466 1 Del Peak 35(17p12) 229 (55%) 184 6.1168e-08 3.66e-05 1.5957e-06 0.000933 2.8124e-35 1.89e-32 1.803e-09 1.11e-06 0.032084 1 1.9e-06 0.00111 1.0566e-10 6.61e-08 3.2016e-08 1.92e-05 0.36262 1 0.7291 1 Del Peak 36(17q24.3) 59 (14%) 354 0.10177 1 0.67597 1 0.0034819 1 0.011753 1 0.50305 1 0.12138 1 0.0032861 1 0.032904 1 0.68104 1 0.97867 1 Del Peak 37(18p11.31) 220 (53%) 193 1.5056e-12 9.71e-10 3.6545e-09 2.23e-06 1.9303e-42 1.3e-39 3.1072e-13 2.02e-10 0.036885 1 7.236e-05 0.0404 3.1119e-17 2.06e-14 8.1919e-10 5.07e-07 0.48029 1 0.84148 1 Del Peak 38(18q12.2) 247 (60%) 166 8.3716e-11 5.25e-08 1.0824e-09 6.69e-07 1.8686e-45 1.27e-42 8.9817e-16 5.9e-13 0.091817 1 6.9882e-05 0.0391 7.6643e-16 5.04e-13 1.0742e-08 6.52e-06 0.44898 1 0.86493 1 Del Peak 39(18q21.2) 260 (63%) 153 3.0616e-10 1.91e-07 6.8492e-10 4.25e-07 1.5149e-45 1.03e-42 3.2902e-12 2.11e-09 0.024586 1 4.5081e-05 0.0256 8.7386e-13 5.66e-10 7.1392e-07 0.000421 0.051698 1 0.90124 1 Del Peak 40(18q22.1) 260 (63%) 153 6.923e-11 4.35e-08 3.6479e-09 2.23e-06 1.5789e-47 1.07e-44 2.0207e-12 1.3e-09 0.039653 1 3.1605e-05 0.018 4.0541e-12 2.59e-09 2.7626e-07 0.000164 0.074601 1 0.91179 1 Del Peak 41(19p13.3) 57 (14%) 356 0.26846 1 0.19814 1 0.0036238 1 0.56533 1 0.07645 1 0.11389 1 0.051162 1 0.024394 1 0.5818 1 0.016593 1 Del Peak 42(20p12.1) 79 (19%) 334 0.065611 1 0.17327 1 1.3778e-13 8.97e-11 0.0040359 1 0.50149 1 0.15111 1 0.00014971 0.0817 0.0067416 1 0.093065 1 0.10088 1 Del Peak 43(21q11.2) 125 (30%) 288 0.002984 1 0.093343 1 3.3671e-09 2.06e-06 0.030185 1 0.78777 1 0.31858 1 0.00089656 0.455 0.018699 1 0.92346 1 0.4701 1 Del Peak 44(22q13.32) 138 (33%) 275 0.00042836 0.228 0.00074726 0.384 9.7641e-13 6.32e-10 0.0049006 1 0.38196 1 0.052356 1 0.0022174 1 0.0010638 0.535 0.39369 1 0.069036 1