Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.074 0.174 0.376 44.0 -9999.0 0.0 44.0 KIRREL -0.047 0.177 -9999.0 0.0 -0.631 16.0 16.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.074 0.175 -9999.0 0.0 -0.376 44.0 44.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.05 0.141 -9999.0 0.0 -0.386 21.0 21.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.025 0.113 -9999.0 0.0 -0.319 19.0 19.0 FYN -0.049 0.134 -9999.0 0.0 -0.367 22.0 22.0 mol:Ca2+ -0.067 0.13 -9999.0 0.0 -0.383 21.0 21.0 mol:DAG -0.067 0.131 -9999.0 0.0 -0.385 21.0 21.0 NPHS2 -0.02 0.085 -9999.0 0.0 -0.444 7.0 7.0 mol:IP3 -0.067 0.131 -9999.0 0.0 -0.385 21.0 21.0 regulation of endocytosis -0.039 0.127 -9999.0 0.0 -0.344 21.0 21.0 Nephrin/NEPH1/podocin/Cholesterol -0.057 0.141 -9999.0 0.0 -0.393 21.0 21.0 establishment of cell polarity -0.074 0.174 -9999.0 0.0 -0.376 44.0 44.0 Nephrin/NEPH1/podocin/NCK1-2 -0.037 0.13 -9999.0 0.0 -0.349 21.0 21.0 Nephrin/NEPH1/beta Arrestin2 -0.039 0.129 -9999.0 0.0 -0.348 21.0 21.0 NPHS1 -0.064 0.169 -9999.0 0.0 -0.455 29.0 29.0 Nephrin/NEPH1/podocin -0.049 0.135 -9999.0 0.0 -0.369 22.0 22.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.05 0.141 -9999.0 0.0 -0.386 21.0 21.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.05 0.141 -9999.0 0.0 -0.386 21.0 21.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.061 0.168 -9999.0 0.0 -0.441 24.0 24.0 cytoskeleton organization -0.03 0.135 -9999.0 0.0 -0.376 20.0 20.0 Nephrin/NEPH1 -0.051 0.126 -9999.0 0.0 -0.35 21.0 21.0 Nephrin/NEPH1/ZO-1 -0.067 0.133 -9999.0 0.0 -0.392 20.0 20.0