Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.002 0.102 0.271 29.0 -0.201 2.0 31.0 KIRREL 0.016 0.034 -9999.0 0.0 -0.398 1.0 1.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.002 0.102 0.202 2.0 -0.272 29.0 31.0 PLCG1 0.014 0.012 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.02 0.008 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.023 0.003 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.024 0.087 -9999.0 0.0 -0.209 26.0 26.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.008 0.042 0.147 1.0 -0.192 1.0 2.0 FYN -0.002 0.08 0.216 12.0 -0.177 26.0 38.0 mol:Ca2+ 0.009 0.075 -9999.0 0.0 -0.209 20.0 20.0 mol:DAG 0.009 0.075 -9999.0 0.0 -0.21 20.0 20.0 NPHS2 -0.008 0.043 -9999.0 0.0 -0.394 2.0 2.0 mol:IP3 0.009 0.075 -9999.0 0.0 -0.21 20.0 20.0 regulation of endocytosis 0.014 0.07 0.18 2.0 -0.168 26.0 28.0 Nephrin/NEPH1/podocin/Cholesterol 0.012 0.081 0.181 2.0 -0.206 26.0 28.0 establishment of cell polarity -0.002 0.102 0.201 2.0 -0.271 29.0 31.0 Nephrin/NEPH1/podocin/NCK1-2 0.035 0.085 -9999.0 0.0 -0.191 26.0 26.0 Nephrin/NEPH1/beta Arrestin2 0.016 0.072 0.187 2.0 -0.169 26.0 28.0 NPHS1 -0.02 0.132 0.272 2.0 -0.4 25.0 27.0 Nephrin/NEPH1/podocin 0.015 0.072 0.183 2.0 -0.177 26.0 28.0 TJP1 0.023 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.024 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.024 0.002 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.01 0.076 -9999.0 0.0 -0.211 20.0 20.0 CD2AP 0.024 0.002 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.023 0.087 0.197 2.0 -0.209 26.0 28.0 GRB2 0.023 0.003 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.015 0.081 0.217 11.0 -0.189 27.0 38.0 cytoskeleton organization -0.004 0.052 0.176 2.0 -0.265 1.0 3.0 Nephrin/NEPH1 0.004 0.072 0.166 2.0 -0.183 29.0 31.0 Nephrin/NEPH1/ZO-1 0.013 0.087 0.192 2.0 -0.222 26.0 28.0