Molecular subtypes CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL nCNV (%) nWild-Type Chi-square test_P Chi-square test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Amp Peak 1(1q21.2) 82 (23%) 270 8.5112e-11 4.55e-08 2.627e-08 1.36e-05 0.47319 1 0.71766 1 0.00050944 0.23 0.0031587 1 0.00013618 0.0636 0.53467 1 Amp Peak 2(2q11.2) 74 (21%) 278 2.497e-08 1.29e-05 1.7082e-08 8.87e-06 0.99085 1 0.29511 1 0.011931 1 0.080673 1 0.0031888 1 0.10481 1 Amp Peak 3(2q31.2) 72 (20%) 280 1.2625e-10 6.74e-08 9.3737e-09 4.89e-06 0.80315 1 0.50916 1 0.31834 1 0.10983 1 0.22992 1 0.51905 1 Amp Peak 4(3q26.33) 264 (75%) 88 2.9435e-13 1.6e-10 8.7128e-05 0.0413 0.24361 1 0.19274 1 0.0012816 0.551 0.00046752 0.212 0.0010269 0.447 0.068566 1 Amp Peak 5(5p15.33) 157 (45%) 195 1.3128e-11 7.08e-09 0.025648 1 0.62408 1 0.28223 1 0.683 1 0.32024 1 0.68097 1 0.63795 1 Amp Peak 6(5p12) 131 (37%) 221 3.4758e-12 1.88e-09 0.018165 1 0.47808 1 1 1 0.89962 1 0.38844 1 0.84119 1 0.90487 1 Amp Peak 7(6p12.1) 70 (20%) 282 0.00019536 0.0908 0.0028032 1 0.3028 1 0.46985 1 0.98336 1 0.8023 1 0.92805 1 0.0166 1 Amp Peak 8(6q12) 62 (18%) 290 0.00040012 0.182 0.013845 1 0.81119 1 0.3733 1 1 1 0.82193 1 0.69689 1 0.068181 1 Amp Peak 9(7p11.2) 147 (42%) 205 1.1216e-08 5.84e-06 6.8734e-07 0.000346 0.25991 1 0.83177 1 0.50042 1 0.92323 1 0.864 1 0.087623 1 Amp Peak 10(7q22.1) 121 (34%) 231 6.9866e-15 3.81e-12 5.4553e-08 2.8e-05 0.5988 1 0.56748 1 0.23451 1 0.33488 1 0.01811 1 0.57756 1 Amp Peak 11(8p11.23) 111 (32%) 241 0.035189 1 0.036856 1 0.89679 1 0.62925 1 0.14966 1 0.018247 1 0.020315 1 0.14956 1 Amp Peak 12(8q11.21) 207 (59%) 145 1.7966e-06 0.000895 0.011129 1 0.03226 1 0.51802 1 0.0011291 0.49 0.00066431 0.296 0.002403 1 0.0040338 1 Amp Peak 13(8q24.21) 254 (72%) 98 3.3119e-10 1.76e-07 0.00010584 0.0497 0.18972 1 0.91692 1 0.00010228 0.0482 0.00013544 0.0634 0.012799 1 0.0011423 0.495 Amp Peak 14(9p23) 83 (24%) 269 3.1858e-05 0.0155 0.78566 1 0.65522 1 0.88824 1 0.099338 1 0.227 1 0.36467 1 0.93661 1 Amp Peak 15(9p13.3) 95 (27%) 257 5.0563e-05 0.0244 0.22203 1 0.38958 1 0.25442 1 0.0070808 1 0.037917 1 0.0059889 1 0.068386 1 Amp Peak 16(11p13) 69 (20%) 283 5.6581e-05 0.0272 0.097141 1 0.18692 1 0.053918 1 0.63051 1 0.16315 1 0.40251 1 0.024643 1 Amp Peak 17(11q13.3) 164 (47%) 188 1.7288e-27 9.63e-25 0.00089654 0.394 0.90147 1 0.28425 1 0.36071 1 0.50384 1 0.62675 1 0.11041 1 Amp Peak 18(12p13.33) 118 (34%) 234 2.8492e-10 1.52e-07 1.2841e-05 0.00628 0.27581 1 0.35153 1 0.0091238 1 0.0010119 0.441 0.0017731 0.754 0.6961 1 Amp Peak 19(12q15) 72 (20%) 280 0.00050814 0.23 0.0084226 1 0.060942 1 0.19277 1 0.090004 1 0.045857 1 0.49783 1 0.83816 1 Amp Peak 20(13q22.1) 72 (20%) 280 0.00026247 0.121 8.4301e-05 0.0401 0.018087 1 0.20522 1 0.23284 1 0.0924 1 0.09537 1 0.13473 1 Amp Peak 21(15q26.3) 75 (21%) 277 0.000327 0.151 0.21738 1 0.26329 1 0.62361 1 0.92275 1 0.41588 1 0.91822 1 0.45668 1 Amp Peak 22(17q12) 63 (18%) 289 8.1992e-08 4.2e-05 0.00011155 0.0523 0.62283 1 0.72953 1 0.016761 1 0.030759 1 0.031294 1 0.61526 1 Amp Peak 23(18p11.31) 108 (31%) 244 7.5847e-07 0.00038 0.0031528 1 0.96239 1 0.76598 1 0.26152 1 0.20601 1 0.57771 1 0.97402 1 Amp Peak 24(18q11.2) 74 (21%) 278 0.017365 1 0.033009 1 0.15741 1 0.46194 1 1 1 0.68887 1 0.16945 1 0.34275 1 Amp Peak 25(20q11.22) 155 (44%) 197 4.8579e-06 0.0024 0.022198 1 0.84515 1 0.44182 1 0.012787 1 0.085422 1 0.2564 1 0.016892 1 Del Peak 1(1p36.13) 69 (20%) 283 1.4356e-11 7.71e-09 5.3785e-15 2.94e-12 0.022519 1 0.73943 1 3.0294e-05 0.0148 0.00071584 0.318 0.00034954 0.16 0.14105 1 Del Peak 2(1p13.2) 85 (24%) 267 3.101e-10 1.65e-07 8.6221e-10 4.56e-07 0.012405 1 0.11798 1 0.0054596 1 0.09271 1 8.457e-05 0.0402 0.82787 1 Del Peak 3(1q44) 30 (9%) 322 0.13915 1 0.17517 1 0.85891 1 0.93136 1 0.062774 1 0.013281 1 0.0047114 1 0.24475 1 Del Peak 4(2q21.2) 46 (13%) 306 0.71687 1 0.027827 1 0.91033 1 1 1 0.015371 1 0.0056384 1 0.0003553 0.162 0.11473 1 Del Peak 5(2q22.1) 78 (22%) 274 0.2975 1 0.0064758 1 0.29043 1 0.5224 1 0.051329 1 0.029155 1 0.090866 1 0.044006 1 Del Peak 6(2q36.2) 104 (30%) 248 5.4004e-08 2.78e-05 5.6852e-06 0.0028 0.11414 1 0.53143 1 0.00063648 0.285 0.0012545 0.541 0.0035977 1 0.23158 1 Del Peak 7(3p25.3) 247 (70%) 105 7.6657e-25 4.25e-22 2.9222e-10 1.55e-07 0.2132 1 0.38968 1 0.013367 1 0.063212 1 0.13747 1 0.00066436 0.296 Del Peak 8(3p14.2) 263 (75%) 89 2.4918e-29 1.4e-26 8.8083e-08 4.5e-05 0.25943 1 0.49976 1 0.11513 1 0.16112 1 0.5212 1 0.039397 1 Del Peak 9(3p14.2) 263 (75%) 89 2.4918e-29 1.4e-26 5.7076e-07 0.000289 0.21634 1 0.38638 1 0.11513 1 0.16112 1 0.5212 1 0.039397 1 Del Peak 10(3p12.2) 249 (71%) 103 6.7678e-29 3.78e-26 4.0436e-09 2.13e-06 0.85344 1 0.68385 1 0.24092 1 0.46324 1 0.30398 1 0.17824 1 Del Peak 11(4p15.2) 150 (43%) 202 3.0525e-12 1.65e-09 5.9825e-07 0.000302 0.048294 1 0.12972 1 0.040558 1 0.012897 1 0.0076867 1 0.62008 1 Del Peak 12(4q22.1) 117 (33%) 235 8.6717e-09 4.54e-06 6.4957e-07 0.000327 0.13025 1 0.65057 1 0.37116 1 0.2052 1 0.30053 1 0.67484 1 Del Peak 13(4q35.2) 145 (41%) 207 7.5109e-09 3.94e-06 2.9651e-05 0.0145 0.096178 1 0.53441 1 0.2748 1 0.35295 1 0.21612 1 0.46187 1 Del Peak 14(5q11.2) 142 (40%) 210 5.2732e-17 2.91e-14 1.3467e-12 7.3e-10 0.018553 1 0.6148 1 0.040089 1 0.00076743 0.34 0.069693 1 0.52235 1 Del Peak 15(5q35.3) 134 (38%) 218 7.2039e-18 3.98e-15 4.2509e-14 2.32e-11 0.41879 1 0.064507 1 0.014627 1 0.00047704 0.216 0.23123 1 0.7426 1 Del Peak 16(6p25.3) 68 (19%) 284 0.0019466 0.825 0.00033012 0.152 0.072714 1 0.13295 1 0.0075151 1 0.37979 1 0.11484 1 0.73961 1 Del Peak 17(7q31.1) 54 (15%) 298 0.00091832 0.403 0.026114 1 0.1704 1 0.58095 1 0.36345 1 0.60935 1 0.62379 1 0.42062 1 Del Peak 18(7q36.1) 86 (24%) 266 0.00018192 0.0848 0.33047 1 0.0051092 1 0.27657 1 0.9573 1 0.67433 1 0.86869 1 0.41862 1 Del Peak 19(8p23.2) 201 (57%) 151 2.1716e-15 1.19e-12 3.8374e-05 0.0186 0.13389 1 0.18778 1 0.016617 1 0.0035288 1 0.11667 1 0.05538 1 Del Peak 20(9p23) 161 (46%) 191 1.1576e-16 6.36e-14 5.4222e-09 2.85e-06 0.53765 1 0.85064 1 0.73968 1 0.49317 1 0.80244 1 0.72233 1 Del Peak 21(9p21.3) 204 (58%) 148 2.7068e-13 1.47e-10 2.8251e-09 1.49e-06 0.70654 1 0.42258 1 0.39019 1 0.46183 1 0.6975 1 0.61996 1 Del Peak 22(9q21.11) 65 (18%) 287 2.8637e-08 1.48e-05 0.00096226 0.421 0.95975 1 0.9265 1 0.88221 1 0.67272 1 0.70833 1 0.01115 1 Del Peak 23(9q34.3) 56 (16%) 296 0.0003331 0.153 0.031639 1 0.71183 1 0.10819 1 0.85073 1 0.40851 1 0.27527 1 0.086088 1 Del Peak 24(10p15.3) 114 (32%) 238 5.457e-06 0.00269 0.029339 1 0.5045 1 0.15506 1 0.32749 1 0.30691 1 0.26381 1 0.61935 1 Del Peak 25(10p11.21) 107 (30%) 245 9.7948e-06 0.00481 0.14501 1 0.22533 1 0.065174 1 0.70229 1 0.97498 1 0.54662 1 0.51881 1 Del Peak 26(10q23.31) 89 (25%) 263 1.5452e-06 0.000771 0.004161 1 0.17919 1 0.54795 1 0.024871 1 0.012786 1 0.037608 1 0.67334 1 Del Peak 27(11p15.4) 110 (31%) 242 1.5994e-08 8.32e-06 0.00052338 0.236 0.47097 1 0.45787 1 0.0022763 0.958 0.0070965 1 0.00092664 0.406 0.37457 1 Del Peak 28(11q14.1) 112 (32%) 240 4.774e-25 2.65e-22 0.085114 1 0.19297 1 0.76868 1 0.010529 1 0.036854 1 0.48462 1 0.55104 1 Del Peak 29(11q23.1) 169 (48%) 183 7.7044e-18 4.25e-15 8.4538e-07 0.000423 0.16922 1 0.25442 1 0.00081497 0.36 0.00023024 0.107 0.13173 1 0.27415 1 Del Peak 30(12q24.33) 40 (11%) 312 0.04272 1 0.064574 1 0.08201 1 0.74803 1 0.85888 1 0.77501 1 0.97659 1 0.34549 1 Del Peak 31(13q12.11) 159 (45%) 193 2.628e-11 1.41e-08 7.2846e-07 0.000366 0.27162 1 0.37108 1 0.053034 1 0.028941 1 0.47818 1 0.88899 1 Del Peak 32(13q14.2) 149 (42%) 203 2.8634e-06 0.00142 5.8809e-07 0.000298 0.15108 1 0.27524 1 5.702e-05 0.0274 6.4644e-05 0.0309 0.0085658 1 0.95356 1 Del Peak 33(14q11.2) 51 (14%) 301 0.00061346 0.275 0.0061601 1 0.3801 1 0.51483 1 0.46295 1 0.3287 1 0.064196 1 0.18476 1 Del Peak 34(14q32.32) 53 (15%) 299 0.026684 1 1.4205e-07 7.23e-05 0.098444 1 0.41296 1 0.00024216 0.112 9.7977e-05 0.0462 0.0012292 0.531 0.074433 1 Del Peak 35(15q15.1) 79 (22%) 273 0.0014049 0.601 0.77789 1 0.29349 1 0.16101 1 0.022578 1 0.062757 1 0.12582 1 0.26207 1 Del Peak 36(16q12.1) 62 (18%) 290 0.0092222 1 1.1258e-07 5.74e-05 0.74632 1 0.089598 1 7.1021e-08 3.64e-05 3.9142e-07 0.000199 0.00032957 0.152 0.011963 1 Del Peak 37(16q23.3) 72 (20%) 280 0.016727 1 0.00083917 0.37 0.50372 1 0.019585 1 0.00060143 0.27 8.8834e-05 0.042 0.01354 1 0.22313 1 Del Peak 38(17q25.3) 42 (12%) 310 0.47692 1 0.12256 1 0.4739 1 1 1 0.036979 1 0.061224 1 0.032151 1 0.076339 1 Del Peak 39(18q21.2) 182 (52%) 170 7.2668e-17 4e-14 1.6888e-09 8.92e-07 0.60301 1 0.64213 1 0.0026752 1 0.0072982 1 0.0021919 0.925 0.016978 1 Del Peak 40(18q23) 198 (56%) 154 8.5661e-20 4.75e-17 1.3766e-11 7.41e-09 0.18301 1 0.38539 1 0.0021609 0.914 0.0033283 1 0.0092432 1 0.038664 1 Del Peak 41(19p13.3) 117 (33%) 235 3.5657e-06 0.00177 0.036842 1 0.31002 1 0.081733 1 0.087593 1 0.76122 1 0.44236 1 0.30487 1 Del Peak 42(19q13.43) 68 (19%) 284 1.0335e-05 0.00506 6.9318e-05 0.0331 0.25553 1 0.084149 1 0.58361 1 0.26181 1 0.10173 1 0.68005 1 Del Peak 43(Xp21.3) 116 (33%) 236 4.3008e-05 0.0208 0.0053235 1 0.42445 1 0.06491 1 0.27514 1 0.041471 1 0.19964 1 0.37789 1 Del Peak 44(Xp11.3) 114 (32%) 238 4.6507e-06 0.0023 5.7969e-05 0.0278 0.34603 1 0.009136 1 0.211 1 0.059839 1 0.094733 1 0.97397 1 Del Peak 45(Xq21.33) 56 (16%) 296 0.0016762 0.714 0.0016593 0.709 0.025525 1 0.44409 1 0.0013088 0.561 0.012344 1 4.882e-05 0.0236 0.0041863 1