Molecular subtypes CN_CNMF METHLYATION_CNMF MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q 3p gain 5 (8%) 61 0.72059 1 0.69826 1 1 1 0.94236 1 0.35572 1 0.13368 1 3q gain 5 (8%) 61 0.72059 1 0.69826 1 1 1 0.94236 1 0.35572 1 0.13368 1 4p gain 18 (27%) 48 0.38274 1 0.81276 1 4.5618e-05 0.0142 0.00016144 0.0486 0.45547 1 0.10005 1 4q gain 17 (26%) 49 0.36204 1 0.70104 1 0.00017284 0.0519 0.00078384 0.228 0.26188 1 0.097737 1 5p gain 5 (8%) 61 0.54894 1 0.69826 1 1 1 0.83932 1 1 1 0.13368 1 5q gain 5 (8%) 61 0.54894 1 0.69826 1 1 1 0.83932 1 1 1 0.13368 1 7p gain 18 (27%) 48 0.38274 1 0.38415 1 0.0090598 1 0.019103 1 0.64579 1 1 1 7q gain 18 (27%) 48 0.38274 1 0.38415 1 0.0090598 1 0.019103 1 0.64579 1 1 1 8p gain 13 (20%) 53 0.27392 1 0.086484 1 0.027588 1 0.084812 1 0.38997 1 1 1 8q gain 14 (21%) 52 0.15727 1 0.10479 1 0.0099404 1 0.031654 1 0.64869 1 1 1 9p gain 8 (12%) 58 1 1 0.60857 1 0.91094 1 0.8411 1 0.71385 1 0.29802 1 9q gain 8 (12%) 58 1 1 0.60857 1 0.91094 1 0.8411 1 0.71385 1 0.29802 1 11p gain 13 (20%) 53 0.51686 1 0.27062 1 0.00028747 0.0851 0.00015643 0.0472 1 1 0.18649 1 11q gain 14 (21%) 52 0.6059 1 0.27306 1 8.3317e-05 0.0257 2.7835e-05 0.00874 1 1 0.18625 1 12p gain 14 (21%) 52 0.68779 1 0.43722 1 0.012927 1 0.054195 1 0.41417 1 1 1 12q gain 13 (20%) 53 0.76351 1 0.70859 1 0.013508 1 0.019127 1 0.38997 1 0.67517 1 14q gain 16 (24%) 50 0.34021 1 0.55403 1 0.00070572 0.206 0.0033198 0.903 0.44529 1 0.43576 1 15q gain 14 (21%) 52 0.22401 1 0.24905 1 0.0011285 0.324 0.0064571 1 0.80341 1 0.67109 1 16p gain 15 (23%) 51 0.55562 1 0.79974 1 9.2138e-05 0.0282 0.00093591 0.271 0.11187 1 0.10551 1 16q gain 15 (23%) 51 0.55562 1 0.79974 1 9.2138e-05 0.0282 0.00093591 0.271 0.11187 1 0.10551 1 18p gain 14 (21%) 52 0.47487 1 0.29369 1 0.0061976 1 0.019056 1 1 1 0.38645 1 18q gain 13 (20%) 53 0.67133 1 0.58063 1 0.0040916 1 0.01832 1 0.79327 1 1 1 19p gain 11 (17%) 55 0.86679 1 0.83007 1 0.002063 0.571 0.0021875 0.601 0.34683 1 0.33662 1 19q gain 9 (14%) 57 0.71339 1 0.71963 1 0.0026896 0.734 0.0037186 1 0.12557 1 0.34107 1 20p gain 14 (21%) 52 0.22401 1 0.67219 1 0.0046788 1 0.0037669 1 0.41417 1 0.67109 1 20q gain 15 (23%) 51 0.28224 1 0.39728 1 0.0071321 1 0.007431 1 0.61061 1 1 1 21q gain 3 (5%) 63 0.64565 1 NA NA 0.32734 1 0.3326 1 0.76731 1 0.36058 1 22q gain 15 (23%) 51 0.88188 1 0.11643 1 0.074818 1 0.1964 1 0.93195 1 1 1 Xq gain 9 (14%) 57 1 1 0.50262 1 8.8354e-05 0.0271 0.0041691 1 0.2702 1 0.34107 1 1p loss 48 (73%) 18 0.34162 1 5.8851e-06 0.00189 8.2551e-06 0.00264 1.794e-05 0.0057 0.079829 1 0.0010279 0.296 1q loss 47 (71%) 19 0.3196 1 1.0573e-05 0.00337 3.1061e-05 0.00972 6.5948e-05 0.0205 0.031569 1 0.0015701 0.443 2p loss 43 (65%) 23 0.082806 1 4.5713e-06 0.00148 8.3099e-09 2.82e-06 2.255e-07 7.58e-05 0.013246 1 0.00059168 0.174 2q loss 43 (65%) 23 0.082806 1 4.5713e-06 0.00148 8.3099e-09 2.82e-06 2.255e-07 7.58e-05 0.013246 1 0.00059168 0.174 3p loss 7 (11%) 59 0.082637 1 1 1 0.25175 1 0.0055363 1 0.48246 1 0.58064 1 3q loss 6 (9%) 60 0.03256 1 0.5323 1 0.13499 1 0.0012588 0.358 0.34751 1 0.58525 1 5p loss 7 (11%) 59 0.30229 1 0.17498 1 0.03288 1 0.0047778 1 0.19606 1 0.58064 1 5q loss 7 (11%) 59 0.30229 1 0.17498 1 0.03288 1 0.0047778 1 0.19606 1 0.58064 1 6p loss 47 (71%) 19 0.3196 1 0.00013204 0.0401 1.2588e-06 0.000417 2.6697e-05 0.00844 0.031569 1 0.0015701 0.443 6q loss 47 (71%) 19 0.3196 1 0.00013204 0.0401 1.2588e-06 0.000417 2.6697e-05 0.00844 0.031569 1 0.0015701 0.443 8p loss 9 (14%) 57 8.1131e-08 2.73e-05 0.057575 1 0.053142 1 0.0035954 0.974 0.12557 1 0.34107 1 8q loss 8 (12%) 58 5.8622e-07 0.000195 0.038075 1 0.13361 1 0.0043369 1 0.25107 1 0.58572 1 9p loss 8 (12%) 58 1 1 1 1 0.17123 1 0.57907 1 0.71385 1 0.29802 1 9q loss 8 (12%) 58 1 1 1 1 0.17123 1 0.57907 1 0.71385 1 0.29802 1 10p loss 44 (67%) 22 0.26056 1 0.001983 0.553 2.5078e-06 0.00082 3.0256e-06 0.000983 0.19008 1 0.050602 1 10q loss 44 (67%) 22 0.26056 1 0.001983 0.553 2.5078e-06 0.00082 3.0256e-06 0.000983 0.19008 1 0.050602 1 11p loss 5 (8%) 61 1 1 0.59319 1 0.1289 1 0.40773 1 0.60592 1 1 1 11q loss 5 (8%) 61 1 1 0.59319 1 0.1289 1 0.40773 1 0.60592 1 1 1 13q loss 37 (56%) 29 0.11621 1 0.0092328 1 0.0012333 0.351 0.00050604 0.149 0.54777 1 0.036005 1 16p loss 3 (5%) 63 1 1 0.4166 1 0.012566 1 0.0014772 0.418 1 1 1 1 16q loss 4 (6%) 62 0.68502 1 0.65254 1 0.0021853 0.601 8.579e-05 0.0264 1 1 0.45192 1 17p loss 45 (68%) 21 0.15807 1 1.3075e-06 0.00043 2.6135e-09 8.91e-07 3.0024e-07 1e-04 0.0037178 1 0.00025533 0.0761 17q loss 45 (68%) 21 0.15807 1 1.3075e-06 0.00043 2.6135e-09 8.91e-07 3.0024e-07 1e-04 0.0037178 1 0.00025533 0.0761 18p loss 5 (8%) 61 0.25683 1 0.11837 1 0.013408 1 0.0012 0.343 0.60592 1 1 1 18q loss 7 (11%) 59 0.22153 1 0.17498 1 0.048087 1 0.017848 1 0.48246 1 1 1 21q loss 28 (42%) 38 1 1 0.018296 1 0.22985 1 0.037913 1 0.74188 1 0.72234 1 22q loss 5 (8%) 61 0.72059 1 0.11837 1 0.74533 1 0.37957 1 0.35572 1 1 1 Xq loss 33 (50%) 33 0.71256 1 2.4497e-05 0.00777 7.9561e-05 0.0247 0.00021664 0.0648 0.046646 1 0.0020839 0.575