Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.046 0.139 0.424 24.0 -9999.0 0.0 24.0 KIRREL -0.016 0.135 -9999.0 0.0 -0.664 9.0 9.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.047 0.139 -9999.0 0.0 -0.425 24.0 24.0 PLCG1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.034 0.103 -9999.0 0.0 -0.426 9.0 9.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.008 0.083 -9999.0 0.0 -0.335 9.0 9.0 FYN -0.012 0.102 -9999.0 0.0 -0.404 9.0 9.0 mol:Ca2+ -0.034 0.102 -9999.0 0.0 -0.422 9.0 9.0 mol:DAG -0.034 0.103 -9999.0 0.0 -0.424 9.0 9.0 NPHS2 -0.004 0.037 -9999.0 0.0 -0.487 1.0 1.0 mol:IP3 -0.034 0.103 -9999.0 0.0 -0.424 9.0 9.0 regulation of endocytosis -0.029 0.088 -9999.0 0.0 -0.375 9.0 9.0 Nephrin/NEPH1/podocin/Cholesterol -0.035 0.106 -9999.0 0.0 -0.435 9.0 9.0 establishment of cell polarity -0.046 0.139 -9999.0 0.0 -0.424 24.0 24.0 Nephrin/NEPH1/podocin/NCK1-2 -0.03 0.092 -9999.0 0.0 -0.385 9.0 9.0 Nephrin/NEPH1/beta Arrestin2 -0.006 0.097 -9999.0 0.0 -0.379 9.0 9.0 NPHS1 -0.03 0.139 -9999.0 0.0 -0.508 17.0 17.0 Nephrin/NEPH1/podocin -0.032 0.096 -9999.0 0.0 -0.407 9.0 9.0 TJP1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.034 0.103 -9999.0 0.0 -0.426 9.0 9.0 CD2AP 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.034 0.103 -9999.0 0.0 -0.426 9.0 9.0 GRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.037 0.137 -9999.0 0.0 -0.398 19.0 19.0 cytoskeleton organization 0.011 0.101 -9999.0 0.0 -0.4 9.0 9.0 Nephrin/NEPH1 -0.033 0.101 -9999.0 0.0 -0.419 9.0 9.0 Nephrin/NEPH1/ZO-1 -0.036 0.111 -9999.0 0.0 -0.458 9.0 9.0