Molecular subtypes CN_CNMF METHLYATION_CNMF MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Amp Peak 1(1p22.3) 24 (25%) 73 0.068596 1 0.36267 1 0.21758 1 0.11182 1 0.32614 1 0.1111 1 Amp Peak 2(1q22) 72 (74%) 25 0.001258 0.385 0.00057148 0.177 0.13149 1 0.58143 1 0.44801 1 0.69561 1 Amp Peak 3(1q42.3) 65 (67%) 32 0.0035909 1 0.010267 1 0.042939 1 0.80185 1 0.49791 1 0.1919 1 Amp Peak 4(2p24.1) 22 (23%) 75 0.24437 1 0.38675 1 0.70159 1 0.25045 1 0.16794 1 0.024505 1 Amp Peak 5(2q33.1) 20 (21%) 77 0.26268 1 0.5758 1 0.49073 1 0.77087 1 0.7891 1 0.14087 1 Amp Peak 6(3q26.31) 20 (21%) 77 0.0056831 1 0.32796 1 0.12627 1 1 1 0.55709 1 0.12118 1 Amp Peak 7(4q31.3) 8 (8%) 89 0.52369 1 1 1 0.4648 1 0.12219 1 0.20042 1 0.40225 1 Amp Peak 8(5p15.33) 48 (49%) 49 0.0027782 0.842 0.52232 1 0.16535 1 0.093812 1 0.36665 1 0.64529 1 Amp Peak 9(5q35.3) 37 (38%) 60 0.031522 1 0.41593 1 0.35816 1 0.4431 1 0.92132 1 0.88946 1 Amp Peak 10(6p25.2) 42 (43%) 55 0.010176 1 0.003345 1 0.11773 1 0.093812 1 0.88967 1 0.54049 1 Amp Peak 11(6p21.1) 43 (44%) 54 0.00087049 0.268 7.4342e-05 0.0234 0.0062322 1 0.33188 1 0.49497 1 0.30549 1 Amp Peak 12(6q12) 32 (33%) 65 0.06508 1 0.028594 1 0.10074 1 1 1 0.084606 1 0.37227 1 Amp Peak 13(7q21.2) 36 (37%) 61 0.25328 1 0.04378 1 0.3972 1 0.20034 1 0.49278 1 0.23302 1 Amp Peak 14(8q13.1) 49 (51%) 48 4.2154e-09 1.34e-06 0.9306 1 0.14924 1 1 1 0.63089 1 0.43639 1 Amp Peak 15(8q24.13) 60 (62%) 37 1.7988e-07 5.7e-05 0.73728 1 0.1779 1 0.62262 1 0.72513 1 0.78943 1 Amp Peak 16(10p15.1) 19 (20%) 78 0.16845 1 0.25585 1 0.27326 1 0.016738 1 0.43431 1 0.23027 1 Amp Peak 17(11q13.3) 17 (18%) 80 0.39596 1 0.48601 1 0.15955 1 0.73189 1 0.085552 1 0.019191 1 Amp Peak 18(12q23.1) 19 (20%) 78 0.00044987 0.14 0.073736 1 0.66832 1 0.13141 1 0.52338 1 0.46865 1 Amp Peak 19(13q32.3) 22 (23%) 75 0.0011042 0.339 0.1282 1 0.37202 1 0.14353 1 0.42807 1 0.28268 1 Amp Peak 20(15q21.3) 15 (15%) 82 0.013005 1 0.36471 1 0.15258 1 0.54163 1 0.93346 1 0.3524 1 Amp Peak 21(15q26.3) 15 (15%) 82 0.035951 1 0.81028 1 0.60981 1 0.54163 1 0.69956 1 0.72287 1 Amp Peak 22(17p11.2) 15 (15%) 82 0.0031277 0.945 0.75527 1 0.25561 1 0.30174 1 0.87136 1 0.17543 1 Amp Peak 23(17q23.1) 40 (41%) 57 0.023037 1 0.51309 1 0.30077 1 0.22006 1 0.51159 1 0.68261 1 Amp Peak 24(17q25.3) 44 (45%) 53 0.00045276 0.141 0.095878 1 0.38845 1 0.81144 1 0.46173 1 0.867 1 Amp Peak 25(19q13.11) 31 (32%) 66 0.041073 1 0.28346 1 0.6859 1 0.30222 1 0.64559 1 0.50706 1 Amp Peak 26(20q13.13) 35 (36%) 62 0.041823 1 0.55619 1 0.0044898 1 0.46072 1 0.88467 1 0.22998 1 Del Peak 1(1p36.32) 45 (46%) 52 0.015868 1 0.014546 1 0.27624 1 0.63122 1 0.32273 1 0.089892 1 Del Peak 2(2q22.1) 10 (10%) 87 0.48907 1 0.39187 1 0.7513 1 0.69048 1 0.063368 1 0.020303 1 Del Peak 3(2q37.3) 16 (16%) 81 0.35718 1 0.56273 1 0.44193 1 0.75007 1 0.064958 1 0.0058368 1 Del Peak 4(3p13) 16 (16%) 81 0.11301 1 0.29187 1 0.0023805 0.724 0.00016288 0.051 0.011156 1 0.11872 1 Del Peak 5(4q24) 41 (42%) 56 8.4746e-05 0.0266 0.13108 1 0.41208 1 0.8094 1 0.21422 1 0.43459 1 Del Peak 6(4q35.1) 42 (43%) 55 0.0020459 0.624 0.046452 1 0.11559 1 0.33662 1 0.28507 1 0.32293 1 Del Peak 7(5q23.1) 14 (14%) 83 0.15623 1 0.22781 1 0.33543 1 0.15168 1 0.31877 1 0.54655 1 Del Peak 8(6q16.3) 36 (37%) 61 0.30398 1 0.70681 1 0.41894 1 0.12712 1 0.45446 1 0.32481 1 Del Peak 9(6q26) 39 (40%) 58 0.16536 1 0.71398 1 0.66898 1 0.12712 1 0.23159 1 0.14378 1 Del Peak 10(8p23.2) 60 (62%) 37 3.6009e-07 0.000114 0.46739 1 0.23431 1 0.46006 1 0.41004 1 0.090725 1 Del Peak 11(9p21.3) 39 (40%) 58 0.15452 1 0.77245 1 0.78091 1 0.33662 1 0.1224 1 0.53534 1 Del Peak 12(10p15.3) 8 (8%) 89 0.7313 1 0.89254 1 0.4204 1 0.63368 1 0.20042 1 0.63763 1 Del Peak 13(10q23.31) 31 (32%) 66 0.033748 1 0.63741 1 0.0054836 1 0.07223 1 0.33917 1 0.010563 1 Del Peak 14(10q24.33) 29 (30%) 68 0.050979 1 0.57684 1 0.0055962 1 0.064677 1 0.03782 1 0.023145 1 Del Peak 15(11q14.1) 18 (19%) 79 0.57631 1 0.75106 1 0.42921 1 0.55367 1 0.68182 1 0.88633 1 Del Peak 16(12p12.1) 23 (24%) 74 0.18407 1 0.86345 1 0.24752 1 0.17713 1 0.18633 1 0.16305 1 Del Peak 17(12q24.33) 16 (16%) 81 0.48413 1 1 1 0.59314 1 0.75007 1 0.13166 1 0.60542 1 Del Peak 18(13q14.2) 43 (44%) 54 0.0068238 1 0.14812 1 0.052765 1 0.053794 1 0.058182 1 0.32293 1 Del Peak 19(14q23.3) 36 (37%) 61 0.022044 1 0.29169 1 0.4006 1 0.048155 1 0.51868 1 0.084942 1 Del Peak 20(15q15.1) 18 (19%) 79 0.0037474 1 0.59134 1 0.36376 1 0.034058 1 0.82941 1 0.68816 1 Del Peak 21(16q23.1) 42 (43%) 55 0.00074979 0.232 0.0081919 1 0.011437 1 0.053794 1 0.22291 1 0.027501 1 Del Peak 22(17p12) 57 (59%) 40 0.092119 1 0.51528 1 0.1213 1 0.13903 1 0.012426 1 0.0067093 1 Del Peak 23(18q21.2) 18 (19%) 79 0.11758 1 0.12601 1 0.13165 1 1 1 0.63427 1 0.83941 1 Del Peak 24(19p13.3) 20 (21%) 77 0.051607 1 0.10112 1 0.50323 1 0.26652 1 0.074873 1 0.13151 1 Del Peak 25(22q12.1) 18 (19%) 79 0.031756 1 0.23946 1 0.12299 1 0.23524 1 1 1 0.88991 1 Del Peak 26(22q13.32) 24 (25%) 73 0.020642 1 0.38141 1 0.041456 1 1 1 0.81874 1 0.54177 1 Del Peak 27(Xq27.3) 14 (14%) 83 0.0077355 1 0.12631 1 0.21636 1 0.3359 1 0.44212 1 0.64534 1