Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.034 0.054 0.248 4.0 -0.236 15.0 19.0 KIRREL 0.017 0.04 -9999.0 0.0 -0.345 4.0 4.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.034 0.054 0.236 15.0 -0.249 4.0 19.0 PLCG1 0.021 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.02 0.006 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.021 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.05 0.053 0.221 15.0 -0.189 4.0 19.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.013 0.037 0.163 2.0 -0.193 5.0 7.0 FYN 0.017 0.087 0.213 49.0 -0.18 4.0 53.0 mol:Ca2+ 0.048 0.051 0.213 15.0 -0.187 4.0 19.0 mol:DAG 0.049 0.052 0.217 15.0 -0.188 4.0 19.0 NPHS2 -0.004 0.024 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.049 0.052 0.217 15.0 -0.188 4.0 19.0 regulation of endocytosis 0.035 0.046 0.201 14.0 -0.174 4.0 18.0 Nephrin/NEPH1/podocin/Cholesterol 0.04 0.048 0.206 15.0 -0.182 4.0 19.0 establishment of cell polarity 0.034 0.054 0.236 15.0 -0.248 4.0 19.0 Nephrin/NEPH1/podocin/NCK1-2 0.058 0.054 0.223 15.0 -0.176 4.0 19.0 Nephrin/NEPH1/beta Arrestin2 0.037 0.047 0.209 14.0 -0.176 4.0 18.0 NPHS1 0.037 0.076 0.34 19.0 -9999.0 0.0 19.0 Nephrin/NEPH1/podocin 0.037 0.046 0.208 15.0 -0.181 4.0 19.0 TJP1 0.021 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.021 0.003 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.022 0.002 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.05 0.053 0.221 15.0 -0.189 4.0 19.0 CD2AP 0.021 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.05 0.052 0.221 14.0 -0.184 4.0 18.0 GRB2 0.021 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 0.007 0.098 0.272 29.0 -0.183 21.0 50.0 cytoskeleton organization -0.004 0.052 0.216 10.0 -0.211 4.0 14.0 Nephrin/NEPH1 0.029 0.042 0.193 15.0 -0.166 4.0 19.0 Nephrin/NEPH1/ZO-1 0.04 0.049 0.22 14.0 -0.199 4.0 18.0