Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.09	0.185	0.323	6.0	-0.515	29.0	35.0
IHH	-0.16	0.213	0.337	4.0	-0.382	164.0	168.0
SHH Np/Cholesterol/GAS1	-0.038	0.06	0.115	1.0	-0.189	46.0	47.0
LRPAP1	0.021	0.004	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.038	0.06	0.188	46.0	-0.114	1.0	47.0
SMO/beta Arrestin2	-0.146	0.181	0.319	1.0	-0.425	40.0	41.0
SMO	-0.147	0.186	0.343	1.0	-0.339	137.0	138.0
AKT1	-0.08	0.146	-9999.0	0.0	-0.503	23.0	23.0
ARRB2	0.02	0.006	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.021	0.004	-9999.0	0.0	-9999.0	0.0	0.0
ADRBK1	0.021	0.004	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.146	0.184	0.342	1.0	-0.335	138.0	139.0
STIL	-0.083	0.145	0.264	9.0	-0.319	44.0	53.0
DHH N/PTCH2	0.014	0.067	-9999.0	0.0	-0.238	23.0	23.0
DHH N/PTCH1	-0.106	0.153	-9999.0	0.0	-0.359	41.0	41.0
PIK3CA	0.021	0.004	-9999.0	0.0	-9999.0	0.0	0.0
DHH	-0.001	0.087	-9999.0	0.0	-0.336	22.0	22.0
PTHLH	-0.121	0.224	0.388	6.0	-0.573	28.0	34.0
determination of left/right symmetry	-0.146	0.184	0.342	1.0	-0.335	138.0	139.0
PIK3R1	0.021	0.005	-9999.0	0.0	-9999.0	0.0	0.0
skeletal system development	-0.12	0.223	0.388	6.0	-0.568	28.0	34.0
IHH N/Hhip	-0.232	0.181	0.212	3.0	-0.324	264.0	267.0
DHH N/Hhip	-0.126	0.146	-9999.0	0.0	-0.254	194.0	194.0
mol:Cholesterol	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.146	0.184	0.342	1.0	-0.335	138.0	139.0
pancreas development	-0.174	0.178	-9999.0	0.0	-0.336	192.0	192.0
HHAT	0.018	0.028	-9999.0	0.0	-0.336	2.0	2.0
PI3K	0.03	0.009	-9999.0	0.0	-9999.0	0.0	0.0
EntrezGene:84976	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.011	0.06	-9999.0	0.0	-0.336	10.0	10.0
somite specification	-0.146	0.184	0.342	1.0	-0.335	138.0	139.0
SHH Np/Cholesterol/PTCH1	-0.105	0.134	0.176	2.0	-0.329	50.0	52.0
SHH Np/Cholesterol/PTCH2	-0.035	0.055	0.115	1.0	-0.183	41.0	42.0
SHH Np/Cholesterol/Megalin	-0.07	0.091	0.115	1.0	-0.204	103.0	104.0
SHH	-0.041	0.072	0.155	1.0	-0.238	41.0	42.0
catabolic process	-0.107	0.16	0.232	3.0	-0.399	29.0	32.0
SMO/Vitamin D3	-0.121	0.173	0.37	2.0	-0.405	45.0	47.0
SHH Np/Cholesterol/Hhip	-0.11	0.104	0.115	1.0	-0.204	179.0	180.0
LRP2	-0.072	0.159	0.331	1.0	-0.336	93.0	94.0
receptor-mediated endocytosis	-0.167	0.184	0.303	2.0	-0.409	91.0	93.0
SHH Np/Cholesterol/BOC	-0.034	0.053	0.115	1.0	-0.183	39.0	40.0
SHH Np/Cholesterol/CDO	-0.036	0.059	0.115	1.0	-0.19	42.0	43.0
mesenchymal cell differentiation	0.11	0.103	0.203	179.0	-0.114	1.0	180.0
mol:Vitamin D3	-0.093	0.154	0.36	5.0	-0.343	45.0	50.0
IHH N/PTCH2	-0.1	0.132	0.212	4.0	-0.216	193.0	197.0
CDON	0.013	0.05	-9999.0	0.0	-0.336	7.0	7.0
IHH N/PTCH1	-0.098	0.173	0.271	3.0	-0.402	29.0	32.0
Megalin/LRPAP1	-0.037	0.118	0.238	1.0	-0.237	90.0	91.0
PTCH2	0.021	0.019	-9999.0	0.0	-0.336	1.0	1.0
SHH Np/Cholesterol	-0.03	0.054	-9999.0	0.0	-0.177	41.0	41.0
PTCH1	-0.107	0.161	0.233	3.0	-0.4	29.0	32.0
HHIP	-0.174	0.178	-9999.0	0.0	-0.336	192.0	192.0