Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.024 0.103 0.471 13.0 -9999.0 0.0 13.0 KIRREL 0.003 0.067 -9999.0 0.0 -0.748 2.0 2.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.024 0.104 -9999.0 0.0 -0.472 13.0 13.0 PLCG1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.02 0.079 -9999.0 0.0 -9999.0 0.0 0.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.006 0.048 -9999.0 0.0 -9999.0 0.0 0.0 FYN -0.0 0.075 -9999.0 0.0 -0.404 2.0 2.0 mol:Ca2+ -0.019 0.079 -9999.0 0.0 -0.424 2.0 2.0 mol:DAG -0.02 0.079 -9999.0 0.0 -0.426 2.0 2.0 NPHS2 -0.003 0.056 -9999.0 0.0 -0.622 2.0 2.0 mol:IP3 -0.02 0.079 -9999.0 0.0 -0.426 2.0 2.0 regulation of endocytosis -0.016 0.065 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/Cholesterol -0.02 0.081 -9999.0 0.0 -0.435 2.0 2.0 establishment of cell polarity -0.024 0.103 -9999.0 0.0 -0.471 13.0 13.0 Nephrin/NEPH1/podocin/NCK1-2 -0.018 0.071 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/beta Arrestin2 -0.016 0.066 -9999.0 0.0 -9999.0 0.0 0.0 NPHS1 -0.019 0.128 -9999.0 0.0 -0.623 11.0 11.0 Nephrin/NEPH1/podocin -0.017 0.071 -9999.0 0.0 -0.407 2.0 2.0 TJP1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.02 0.079 -9999.0 0.0 -0.427 2.0 2.0 CD2AP 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.02 0.079 -9999.0 0.0 -0.427 2.0 2.0 GRB2 0.01 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.014 0.118 -9999.0 0.0 -0.475 10.0 10.0 cytoskeleton organization 0.013 0.066 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1 -0.017 0.075 -9999.0 0.0 -0.339 13.0 13.0 Nephrin/NEPH1/ZO-1 -0.019 0.082 -9999.0 0.0 -0.46 2.0 2.0