Clinical Features	MRNA_CNMF		MRNA_CHIERARCHICAL		CN_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
APC	57 (83%)	12	0.84989	1	0.77985	1	0.056067	1	0.36218	1	0.59849	1	0.33741	1	1	1
KRAS	38 (55%)	31	0.34215	1	0.17995	1	0.0023343	0.238	0.83044	1	0.81719	1	0.29246	1	0.046474	1
TP53	45 (65%)	24	0.00022892	0.0238	0.0013522	0.139	0.2098	1	0.16036	1	0.60343	1	0.81229	1	0.28827	1
SMAD4	8 (12%)	61	0.10472	1	0.36144	1	0.91418	1	0.15156	1	0.18012	1	0.30921	1	1	1
KIAA1804	9 (13%)	60	0.32197	1	0.5784	1	0.099669	1	1	1	0.81974	1	0.80471	1	1	1
FBXW7	9 (13%)	60	0.14789	1	0.096175	1	0.40917	1	0.68795	1	0.58507	1	0.80471	1	1	1
NRAS	5 (7%)	64	0.85557	1	1	1	0.67453	1	NA	NA	NA	NA	0.096864	1	1	1
TCF7L2	7 (10%)	62	0.883	1	0.68279	1	0.7088	1	0.15242	1	0.52808	1	1	1	1	1
PIK3CA	7 (10%)	62	1	1	0.73108	1	0.81433	1	0.46494	1	0.48826	1	0.34273	1	0.32777	1
OPCML	6 (9%)	63	0.22842	1	0.097181	1	0.50815	1	0.67451	1	0.13046	1	1	1	1	1
SMAD2	5 (7%)	64	1	1	1	1	0.28971	1	0.60727	1	0.028124	1	1	1	1	1
SPATA8	3 (4%)	66	NA	NA	NA	NA	0.38824	1	NA	NA	NA	NA	0.43214	1	0.17605	1
ERBB2	4 (6%)	65	0.54032	1	1	1	0.5764	1	0.67451	1	0.13046	1	1	1	1	1
IL1RAPL2	5 (7%)	64	0.61254	1	0.51898	1	0.78529	1	NA	NA	NA	NA	0.27254	1	1	1
FAM123B	6 (9%)	63	1	1	0.73108	1	0.46322	1	0.15929	1	0.90553	1	1	1	1	1
ZIM3	5 (7%)	64	0.82668	1	0.66769	1	0.43343	1	0.3597	1	0.33719	1	0.3874	1	0.27975	1