Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.009 0.066 0.176 30.0 -9999.0 0.0 30.0 KIRREL 0.004 0.055 -9999.0 0.0 -0.408 4.0 4.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.009 0.066 -9999.0 0.0 -0.177 30.0 30.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.003 0.052 -9999.0 0.0 -0.207 6.0 6.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.013 0.035 -9999.0 0.0 -0.201 4.0 4.0 FYN 0.0 0.041 -9999.0 0.0 -0.194 4.0 4.0 mol:Ca2+ 0.004 0.047 -9999.0 0.0 -0.197 4.0 4.0 mol:DAG 0.005 0.047 -9999.0 0.0 -0.198 4.0 4.0 NPHS2 -0.001 0.009 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.005 0.047 -9999.0 0.0 -0.198 4.0 4.0 regulation of endocytosis 0.01 0.041 -9999.0 0.0 -0.177 4.0 4.0 Nephrin/NEPH1/podocin/Cholesterol -0.003 0.047 -9999.0 0.0 -0.204 4.0 4.0 establishment of cell polarity -0.009 0.066 -9999.0 0.0 -0.176 30.0 30.0 Nephrin/NEPH1/podocin/NCK1-2 0.014 0.044 -9999.0 0.0 -0.174 4.0 4.0 Nephrin/NEPH1/beta Arrestin2 0.011 0.041 -9999.0 0.0 -0.179 4.0 4.0 NPHS1 -0.022 0.082 -9999.0 0.0 -0.252 26.0 26.0 Nephrin/NEPH1/podocin 0.002 0.042 -9999.0 0.0 -0.195 4.0 4.0 TJP1 0.004 0.061 -9999.0 0.0 -0.404 5.0 5.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.005 0.048 -9999.0 0.0 -0.198 4.0 4.0 CD2AP 0.01 0.039 -9999.0 0.0 -0.404 2.0 2.0 Nephrin/NEPH1/podocin/GRB2 0.005 0.048 -9999.0 0.0 -0.198 4.0 4.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.005 0.053 -9999.0 0.0 -0.194 8.0 8.0 cytoskeleton organization 0.015 0.039 -9999.0 0.0 -0.208 4.0 4.0 Nephrin/NEPH1 -0.004 0.045 -9999.0 0.0 -0.195 4.0 4.0 Nephrin/NEPH1/ZO-1 -0.002 0.068 -9999.0 0.0 -0.275 8.0 8.0