Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.007 0.176 0.277 1.0 -0.469 22.0 23.0 MAP3K8 0.024 0.042 0.123 4.0 -0.315 3.0 7.0 FOS -0.011 0.175 0.25 1.0 -0.474 23.0 24.0 PRKCA 0.019 0.06 0.124 2.0 -0.315 7.0 9.0 PTPN7 0.01 0.085 0.124 11.0 -0.315 14.0 25.0 HRAS 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.002 0.108 0.124 12.0 -0.315 24.0 36.0 NRAS 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.051 0.017 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.016 0.177 -9999.0 0.0 -0.535 21.0 21.0 MAP2K1 -0.015 0.14 -9999.0 0.0 -0.356 29.0 29.0 ELK1 0.029 0.003 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.018 0.12 0.157 1.0 -0.35 24.0 25.0 mol:GTP 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 MAPK1 -0.015 0.175 -9999.0 0.0 -0.526 21.0 21.0 RAF1 -0.02 0.125 -9999.0 0.0 -0.344 27.0 27.0 KRAS 0.028 0.005 -9999.0 0.0 -9999.0 0.0 0.0