Clinical feature	Statistical test	Significant genes	Associated with	               	Associated with	
AGE	Spearman correlation test	N=64	older	N=33	younger	N=31
GENDER	t test	N=38	male	N=15	female	N=23
HISTOLOGICAL TYPE	ANOVA test	N=5588	 	 	 	 
RADIATIONS RADIATION REGIMENINDICATION	t test	N=35	yes	N=19	no	N=16
RADIATIONEXPOSURE	t test	N=14	yes	N=2	no	N=12
DISTANT METASTASIS	ANOVA test	N=23	 	 	 	 
EXTRATHYROIDAL EXTENSION	ANOVA test	N=120	 	 	 	 
LYMPH NODE METASTASIS	ANOVA test	N=638	 	 	 	 
COMPLETENESS OF RESECTION	ANOVA test	N=3	 	 	 	 
NUMBER OF LYMPH NODES	Spearman correlation test	N=539	higher number.of.lymph.nodes	N=250	lower number.of.lymph.nodes	N=289
NEOPLASM DISEASESTAGE	ANOVA test	N=133	 	 	 	 
MULTIFOCALITY	t test	N=2	unifocal	N=0	multifocal	N=2
TUMOR SIZE	Spearman correlation test	N=14	higher tumor.size	N=2	lower tumor.size	N=12