Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
BRAF	183 (57%)	140	0.019436	1	3.6198e-38	9.99e-36	9.3991e-07	0.000252	2.5141e-11	6.84e-09	4.0306e-46	1.13e-43	1.5559e-39	4.31e-37	9.8813e-42	2.75e-39	1.0251e-43	2.86e-41
EMG1	6 (2%)	317	0.54831	1	1	1	0.3273	1	0.08457	1	1	1	1	1	1	1	0.77786	1
HRAS	12 (4%)	311	0.0002221	0.0582	1.4785e-06	0.000393	9.2268e-05	0.0243	0.0052894	1	1.3711e-05	0.00362	6.7883e-06	0.0018	1.3113e-06	0.00035	3.8538e-07	0.000104
NRAS	26 (8%)	297	0.0069154	1	6.06e-14	1.67e-11	1	1	0.00058312	0.152	4.6976e-11	1.27e-08	4.0258e-11	1.09e-08	9.1907e-13	2.51e-10	2.4742e-13	6.78e-11
PTTG1IP	4 (1%)	319	1	1	1	1	NA	NA	NA	NA	0.2423	1	0.25238	1	0.46855	1	0.39327	1
RPTN	8 (2%)	315	0.80523	1	0.44207	1	0.26549	1	0.80127	1	0.024895	1	0.41549	1	0.82049	1	0.66632	1
EIF1AX	5 (2%)	318	0.73075	1	0.027828	1	0.44359	1	0.13207	1	0.062103	1	0.010868	1	0.058107	1	0.23623	1
CCDC15	5 (2%)	318	0.73075	1	0.11479	1	1	1	0.38135	1	0.13179	1	0.13568	1	0.62987	1	0.53018	1
ZNF845	6 (2%)	317	0.4201	1	0.63746	1	0.63895	1	0.1252	1	0.94332	1	0.16605	1	0.77748	1	0.32833	1
ZNF878	4 (1%)	319	1	1	0.48745	1	NA	NA	NA	NA	0.045357	1	0.83282	1	0.69083	1	1	1
TG	16 (5%)	307	1	1	0.020467	1	0.34039	1	0.49163	1	0.4061	1	0.29326	1	0.045176	1	0.025284	1
PRB2	6 (2%)	317	1	1	0.63746	1	0.080108	1	0.85072	1	0.47352	1	0.72276	1	0.52176	1	0.59848	1
R3HDM2	4 (1%)	319	0.012437	1	0.062964	1	NA	NA	NA	NA	0.069868	1	0.038822	1	0.01909	1	0.0082166	1
IL32	3 (1%)	320	1	1	0.74157	1	NA	NA	NA	NA	1	1	0.78003	1	0.2018	1	0.64491	1
TMCO2	3 (1%)	320	1	1	0.4158	1	0.77837	1	0.19981	1	0.49189	1	0.30268	1	0.40146	1	0.77764	1
PPTC7	3 (1%)	320	0.079094	1	0.062683	1	NA	NA	NA	NA	0.17163	1	0.091632	1	0.29886	1	0.40307	1
MUC7	5 (2%)	318	0.73075	1	0.37204	1	0.68309	1	0.26003	1	0.80451	1	0.84764	1	0.86564	1	0.62935	1
LYPD3	3 (1%)	320	0.54697	1	0.4158	1	NA	NA	NA	NA	0.49189	1	0.30268	1	0.64414	1	0.77764	1
TMEM90B	3 (1%)	320	0.13479	1	1	1	NA	NA	NA	NA	1	1	0.78003	1	1	1	1	1
ZNF799	5 (2%)	318	0.4648	1	1	1	0.5049	1	1	1	0.59189	1	0.84764	1	0.45092	1	1	1
PPM1D	5 (2%)	318	1	1	1	1	0.77837	1	0.1252	1	0.69331	1	0.84764	1	0.86564	1	0.32923	1
MAP3K3	4 (1%)	319	0.060961	1	0.22421	1	0.45902	1	0.08457	1	0.27362	1	0.1845	1	0.46855	1	0.55528	1
TROAP	3 (1%)	320	1	1	0.74157	1	0.77837	1	0.53454	1	0.74564	1	1	1	0.51933	1	0.40307	1
SYNPO2L	3 (1%)	320	0.54697	1	1	1	NA	NA	NA	NA	1	1	0.78003	1	1	1	1	1
ATAD2	4 (1%)	319	1	1	0.82341	1	NA	NA	NA	NA	0.80791	1	1	1	0.69083	1	1	1
KRAS	3 (1%)	320	1	1	0.062683	1	NA	NA	NA	NA	0.17163	1	0.091632	1	0.061596	1	0.02759	1
SLC5A11	3 (1%)	320	0.54697	1	0.74157	1	NA	NA	NA	NA	NA	NA	NA	NA	0.29886	1	0.40307	1
PRG4	4 (1%)	319	0.22971	1	0.10376	1	NA	NA	NA	NA	0.01279	1	0.14194	1	0.46855	1	0.55528	1
SCUBE2	3 (1%)	320	1	1	0.28125	1	NA	NA	NA	NA	0.31416	1	0.30268	1	0.64414	1	0.52219	1
ZNF479	3 (1%)	320	1	1	0.74157	1	NA	NA	NA	NA	1	1	0.78003	1	0.51933	1	1	1
SREBF2	3 (1%)	320	1	1	0.74157	1	NA	NA	NA	NA	0.56789	1	1	1	0.40146	1	0.77764	1
SLC26A11	3 (1%)	320	0.079094	1	1	1	NA	NA	NA	NA	0.36782	1	0.78003	1	0.77787	1	0.30133	1
TSC22D1	3 (1%)	320	1	1	1	1	NA	NA	NA	NA	0.74564	1	1	1	0.77787	1	0.64491	1
ANKRD30A	5 (2%)	318	0.73075	1	0.46244	1	NA	NA	NA	NA	0.74877	1	0.50714	1	0.74032	1	0.86536	1
FAM155A	4 (1%)	319	0.14362	1	0.15568	1	0.77837	1	0.53454	1	NA	NA	NA	NA	0.037152	1	0.55528	1
SLA	3 (1%)	320	0.54697	1	0.062683	1	0.28597	1	0.28488	1	0.17163	1	0.091632	1	0.061596	1	0.02759	1
ZFHX3	10 (3%)	313	0.17092	1	0.61631	1	0.4801	1	0.63189	1	0.79434	1	0.4373	1	0.61266	1	0.72309	1
ARMCX3	3 (1%)	320	0.54697	1	0.74157	1	NA	NA	NA	NA	0.64643	1	0.21335	1	0.51933	1	0.2024	1
SLC25A45	3 (1%)	320	0.13479	1	1	1	NA	NA	NA	NA	NA	NA	NA	NA	0.2018	1	0.40307	1
COL5A3	6 (2%)	317	0.75178	1	0.31733	1	0.77837	1	0.75837	1	0.044045	1	0.75254	1	0.87666	1	0.52315	1
CDC27	3 (1%)	320	1	1	1	1	NA	NA	NA	NA	0.36782	1	0.044618	1	0.77787	1	0.30133	1