Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.162 0.3 0.695 95.0 -9999.0 0.0 95.0 KIRREL -0.06 0.225 -9999.0 0.0 -0.869 29.0 29.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.162 0.301 -9999.0 0.0 -0.697 95.0 95.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.126 0.235 -9999.0 0.0 -0.54 95.0 95.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.071 0.188 -9999.0 0.0 -0.402 95.0 95.0 FYN -0.106 0.23 -9999.0 0.0 -0.511 95.0 95.0 mol:Ca2+ -0.124 0.232 -9999.0 0.0 -0.534 95.0 95.0 mol:DAG -0.125 0.234 -9999.0 0.0 -0.537 95.0 95.0 NPHS2 -0.014 0.034 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.125 0.234 -9999.0 0.0 -0.537 95.0 95.0 regulation of endocytosis -0.111 0.208 -9999.0 0.0 -0.477 95.0 95.0 Nephrin/NEPH1/podocin/Cholesterol -0.128 0.239 -9999.0 0.0 -0.549 95.0 95.0 establishment of cell polarity -0.162 0.3 -9999.0 0.0 -0.695 95.0 95.0 Nephrin/NEPH1/podocin/NCK1-2 -0.115 0.216 -9999.0 0.0 -0.494 95.0 95.0 Nephrin/NEPH1/beta Arrestin2 -0.113 0.212 -9999.0 0.0 -0.484 95.0 95.0 NPHS1 -0.153 0.327 -9999.0 0.0 -0.851 73.0 73.0 Nephrin/NEPH1/podocin -0.12 0.224 -9999.0 0.0 -0.514 95.0 95.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.126 0.235 -9999.0 0.0 -0.54 95.0 95.0 CD2AP 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.126 0.235 -9999.0 0.0 -0.54 95.0 95.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.107 0.238 -9999.0 0.0 -0.515 97.0 97.0 cytoskeleton organization -0.096 0.248 -9999.0 0.0 -0.534 95.0 95.0 Nephrin/NEPH1 -0.124 0.232 -9999.0 0.0 -0.532 95.0 95.0 Nephrin/NEPH1/ZO-1 -0.135 0.251 -9999.0 0.0 -0.578 95.0 95.0