Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.098 0.243 0.536 92.0 -9999.0 0.0 92.0 KIRREL -0.036 0.181 -9999.0 0.0 -0.705 27.0 27.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.099 0.244 -9999.0 0.0 -0.537 92.0 92.0 PLCG1 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.053 0.201 -9999.0 0.0 -0.43 86.0 86.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.054 0.153 -9999.0 0.0 -0.343 84.0 84.0 FYN -0.063 0.19 0.266 19.0 -0.404 86.0 105.0 mol:Ca2+ -0.054 0.198 -9999.0 0.0 -0.426 85.0 85.0 mol:DAG -0.054 0.199 -9999.0 0.0 -0.428 85.0 85.0 NPHS2 -0.003 0.042 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.054 0.199 -9999.0 0.0 -0.428 85.0 85.0 regulation of endocytosis -0.049 0.178 -9999.0 0.0 -0.382 85.0 85.0 Nephrin/NEPH1/podocin/Cholesterol -0.065 0.194 -9999.0 0.0 -0.427 87.0 87.0 establishment of cell polarity -0.098 0.243 -9999.0 0.0 -0.536 92.0 92.0 Nephrin/NEPH1/podocin/NCK1-2 -0.037 0.193 -9999.0 0.0 -0.397 86.0 86.0 Nephrin/NEPH1/beta Arrestin2 -0.048 0.181 -9999.0 0.0 -0.387 85.0 85.0 NPHS1 -0.107 0.267 -9999.0 0.0 -0.689 70.0 70.0 Nephrin/NEPH1/podocin -0.058 0.186 -9999.0 0.0 -0.406 86.0 86.0 TJP1 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.053 0.2 -9999.0 0.0 -0.43 85.0 85.0 CD2AP 0.027 0.003 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.054 0.199 -9999.0 0.0 -0.43 84.0 84.0 GRB2 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.076 0.19 0.277 17.0 -0.408 87.0 104.0 cytoskeleton organization -0.08 0.196 -9999.0 0.0 -0.449 84.0 84.0 Nephrin/NEPH1 -0.07 0.182 -9999.0 0.0 -0.395 92.0 92.0 Nephrin/NEPH1/ZO-1 -0.067 0.209 -9999.0 0.0 -0.452 88.0 88.0