Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.113 0.229 -9999.0 0.0 -0.53 58.0 58.0 MAP3K8 0.014 0.087 -9999.0 0.0 -0.692 6.0 6.0 FOS -0.082 0.186 0.283 3.0 -0.467 52.0 55.0 PRKCA -0.023 0.161 -9999.0 0.0 -0.691 22.0 22.0 PTPN7 -0.023 0.137 -9999.0 0.0 -0.687 15.0 15.0 HRAS 0.025 0.012 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.002 0.066 -9999.0 0.0 -0.688 2.0 2.0 NRAS 0.025 0.008 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.035 0.031 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.016 0.121 -9999.0 0.0 -0.48 18.0 18.0 MAP2K1 -0.025 0.138 -9999.0 0.0 -0.512 24.0 24.0 ELK1 0.012 0.025 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.019 0.129 -9999.0 0.0 -0.519 23.0 23.0 mol:GTP -0.002 0.004 -9999.0 0.0 -0.007 106.0 106.0 MAPK1 -0.103 0.211 -9999.0 0.0 -0.434 97.0 97.0 RAF1 -0.017 0.126 -9999.0 0.0 -0.505 23.0 23.0 KRAS 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0