Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.003 0.08 0.296 22.0 -9999.0 0.0 22.0 KIRREL -0.009 0.107 -9999.0 0.0 -0.409 23.0 23.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.004 0.08 -9999.0 0.0 -0.296 22.0 22.0 PLCG1 0.025 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.024 0.006 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.025 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.019 0.083 -9999.0 0.0 -0.229 33.0 33.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.002 0.057 -9999.0 0.0 -0.214 22.0 22.0 FYN 0.033 0.113 0.248 62.0 -0.211 22.0 84.0 mol:Ca2+ 0.026 0.067 -9999.0 0.0 -0.218 22.0 22.0 mol:DAG 0.026 0.067 -9999.0 0.0 -0.219 22.0 22.0 NPHS2 0.01 0.021 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.026 0.067 -9999.0 0.0 -0.219 22.0 22.0 regulation of endocytosis 0.022 0.061 -9999.0 0.0 -0.2 22.0 22.0 Nephrin/NEPH1/podocin/Cholesterol 0.016 0.063 -9999.0 0.0 -0.217 22.0 22.0 establishment of cell polarity 0.003 0.08 -9999.0 0.0 -0.296 22.0 22.0 Nephrin/NEPH1/podocin/NCK1-2 0.037 0.068 -9999.0 0.0 -0.201 22.0 22.0 Nephrin/NEPH1/beta Arrestin2 0.024 0.062 -9999.0 0.0 -0.202 22.0 22.0 NPHS1 0.022 0.031 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin 0.018 0.062 0.174 1.0 -0.212 22.0 23.0 TJP1 0.024 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.025 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.025 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.027 0.068 -9999.0 0.0 -0.22 22.0 22.0 CD2AP 0.012 0.074 -9999.0 0.0 -0.403 11.0 11.0 Nephrin/NEPH1/podocin/GRB2 0.026 0.068 -9999.0 0.0 -0.22 22.0 22.0 GRB2 0.024 0.006 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 0.018 0.119 0.253 59.0 -0.21 25.0 84.0 cytoskeleton organization -0.005 0.065 0.198 6.0 -0.235 22.0 28.0 Nephrin/NEPH1 0.007 0.056 -9999.0 0.0 -0.201 22.0 22.0 Nephrin/NEPH1/ZO-1 0.02 0.069 -9999.0 0.0 -0.234 22.0 22.0