Clinical Features Time to Death AGE GENDER RADIATIONS.RADIATION.REGIMENINDICATION DISTANT.METASTASIS LYMPH.NODE.METASTASIS NUMBER.OF.LYMPH.NODES TUMOR.STAGECODE NEOPLASM.DISEASESTAGE nMutated (%) nWild-Type logrank test_P logrank test_Q t-test_P t-test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Chi-square test_P Chi-square test_Q t-test_P t-test_Q t-test_P t-test_Q Chi-square test_P Chi-square test_Q DSPP 26 (3%) 746 0.86849 1 0.16565 1 1 1 1 1 1 1 0.34818 1 0.375 1 NA NA 0.9463 1 PIK3R1 21 (3%) 751 0.17323 1 0.68807 1 1 1 0.80105 1 1 1 7.2713e-06 0.00517 0.080545 1 NA NA 0.22327 1 AKT1 19 (2%) 753 0.19608 1 0.1318 1 1 1 0.18264 1 0.74984 1 0.096927 1 0.90221 1 NA NA 0.28595 1 AOAH 19 (2%) 753 0.28314 1 0.4266 1 1 1 0.035334 1 0.40766 1 0.94455 1 0.28164 1 NA NA 0.18692 1 DCP1B 5 (1%) 767 0.54957 1 0.024965 1 1 1 0.33544 1 0.3854 1 0.17564 1 0.44004 1 NA NA 2.3087e-06 0.00164 GATA3 81 (10%) 691 0.74025 1 0.00021252 0.149 0.58977 1 0.13925 1 0.067268 1 0.41025 1 0.59762 1 NA NA 0.6345 1 MAP3K4 18 (2%) 754 0.98819 1 0.54426 1 1 1 0.58524 1 0.0089027 1 0.85657 1 0.91235 1 NA NA 0.70752 1 MEF2A 14 (2%) 758 0.78758 1 0.52335 1 1 1 0.53723 1 0.69928 1 0.49702 1 0.014186 1 NA NA 0.32092 1 NCOA3 29 (4%) 743 0.46417 1 0.87832 1 1 1 0.66664 1 0.27032 1 0.14804 1 0.17725 1 NA NA 0.47277 1 NCOR2 29 (4%) 743 0.81505 1 0.70604 1 1 1 1 1 0.64732 1 0.89049 1 0.2179 1 NA NA 0.90162 1 NR1H2 18 (2%) 754 0.55649 1 0.71174 1 1 1 1 1 0.0044931 1 0.60483 1 0.9544 1 NA NA 0.018432 1 PIK3CA 261 (34%) 511 0.92244 1 0.024195 1 1 1 0.86213 1 0.36175 1 0.53884 1 0.33878 1 NA NA 0.814 1 RBMX 13 (2%) 759 0.64926 1 0.87534 1 1 1 0.3368 1 0.68686 1 0.88558 1 0.24084 1 NA NA 0.94629 1 TP53 257 (33%) 515 0.45415 1 0.03717 1 0.057514 1 0.43229 1 0.19369 1 0.41052 1 0.41446 1 NA NA 0.94898 1 TPRX1 7 (1%) 765 0.69488 1 0.12346 1 1 1 1 1 0.44269 1 0.63369 1 0.20473 1 NA NA 0.76891 1 ZNF384 14 (2%) 758 0.40825 1 0.012633 1 1 1 1 1 0.446 1 0.96852 1 1.1615e-05 0.00824 NA NA 0.31768 1 RUNX1 25 (3%) 747 0.44903 1 0.60593 1 1 1 0.35342 1 1 1 0.96129 1 0.53211 1 NA NA 0.078465 1 PTEN 29 (4%) 743 0.88888 1 0.4601 1 1 1 0.82962 1 0.2932 1 0.54781 1 0.22125 1 NA NA 0.019318 1 TBX3 18 (2%) 754 0.1847 1 0.015455 1 1 1 1 1 0.47842 1 0.99562 1 0.47153 1 NA NA 0.98471 1 CBFB 16 (2%) 756 0.96844 1 0.72682 1 1 1 1 1 0.16554 1 0.27285 1 0.82134 1 NA NA 0.79241 1 MAP2K4 32 (4%) 740 0.18133 1 0.38435 1 1 1 0.68501 1 1 1 0.35309 1 0.91125 1 NA NA 0.97515 1 CDH1 55 (7%) 717 0.41875 1 0.087282 1 1 1 1 1 0.79762 1 0.035997 1 0.12922 1 NA NA 0.10336 1 MAP3K1 57 (7%) 715 0.7812 1 0.0018623 1 1 1 0.753 1 0.41112 1 0.10077 1 7.2375e-07 0.000516 NA NA 0.53916 1 FOXA1 15 (2%) 757 0.077812 1 0.002505 1 1 1 0.37695 1 0.41252 1 0.87586 1 0.83253 1 NA NA 0.027481 1 MLL3 56 (7%) 716 0.52406 1 0.011952 1 1 1 0.7519 1 0.49206 1 0.6618 1 0.91797 1 NA NA 0.79632 1 ATN1 17 (2%) 755 0.2932 1 0.95709 1 1 1 0.26361 1 0.16554 1 0.94638 1 0.60901 1 NA NA 0.94255 1 SF3B1 14 (2%) 758 0.29147 1 0.73793 1 1 1 0.36861 1 1 1 0.87016 1 0.77777 1 NA NA 0.73668 1 CCDC144NL 8 (1%) 764 5.101e-05 0.0361 0.050958 1 1 1 0.12128 1 1 1 0.47176 1 0.29647 1 NA NA 0.39067 1 MUC12 44 (6%) 728 0.0033713 1 0.37489 1 1 1 1 1 0.0001316 0.0926 0.052971 1 0.056247 1 NA NA 0.15855 1 KRTAP4-7 7 (1%) 765 0.59807 1 0.48422 1 1 1 1 1 0.49471 1 0.53446 1 0.45807 1 NA NA 0.045885 1 ZFP36L1 10 (1%) 762 0.98074 1 0.012429 1 1 1 0.071892 1 1 1 0.97161 1 0.41018 1 NA NA 0.78636 1 NCOR1 31 (4%) 741 0.87798 1 0.93719 1 1 1 1 1 0.1838 1 0.78762 1 0.46214 1 NA NA 0.83101 1 KRAS 6 (1%) 766 0.63944 1 0.071763 1 1 1 0.34723 1 1 1 0.9442 1 0.30815 1 NA NA 0.76065 1 PHLDA1 9 (1%) 763 0.78865 1 0.7499 1 1 1 0.45981 1 1 1 0.37249 1 0.00081744 0.573 NA NA 0.023636 1 VEZF1 8 (1%) 764 0.5814 1 0.087502 1 1 1 0.43154 1 0.54196 1 0.9851 1 0.04249 1 NA NA 0.80422 1 ERBB2 12 (2%) 760 0.13863 1 0.54311 1 0.1183 1 0.74041 1 1 1 0.96711 1 0.52217 1 NA NA 0.77731 1 CTCF 18 (2%) 754 0.1172 1 0.93272 1 1 1 1 1 0.446 1 0.91994 1 0.049822 1 NA NA 0.71173 1 KRTAP9-9 6 (1%) 766 0.5956 1 0.40872 1 1 1 0.18116 1 0.44269 1 0.97705 1 0.29265 1 NA NA 0.86518 1 BCL6B 8 (1%) 764 0.60719 1 0.75079 1 1 1 0.12128 1 0.05472 1 0.80879 1 0.80537 1 NA NA 0.93537 1 CTU2 5 (1%) 767 0.55608 1 0.56742 1 1 1 0.33544 1 1 1 0.96155 1 0.057974 1 NA NA 1.1773e-08 8.42e-06 RB1 14 (2%) 758 0.88137 1 0.11965 1 0.13678 1 0.13148 1 0.68686 1 0.015008 1 0.4594 1 NA NA 0.016939 1 HIST1H3B 7 (1%) 765 0.3945 1 0.28575 1 1 1 0.38219 1 1 1 0.36624 1 0.45151 1 NA NA 0.36381 1 AQP7 8 (1%) 764 0.012207 1 0.66203 1 1 1 0.21466 1 1 1 7.5702e-06 0.00537 0.19597 1 NA NA 0.43454 1 MYB 11 (1%) 761 0.17604 1 0.18074 1 1 1 0.48708 1 1 1 0.99178 1 0.036372 1 NA NA 0.51685 1 E2F4 4 (1%) 768 NA NA 0.36657 1 1 1 0.57732 1 1 1 0.95905 1 NA NA NA NA 0.99305 1 MUC20 10 (1%) 762 0.42109 1 0.16954 1 1 1 0.72337 1 0.58485 1 0.4949 1 0.53279 1 NA NA 0.89209 1 AKD1 19 (2%) 753 0.80758 1 0.47096 1 1 1 0.79362 1 0.40766 1 0.39494 1 0.4373 1 NA NA 0.67009 1 CDKN1B 7 (1%) 765 0.84796 1 0.94383 1 1 1 1 1 0.053485 1 0.012846 1 0.047824 1 NA NA 0.031146 1 KRTAP4-5 4 (1%) 768 0.59584 1 0.19396 1 1 1 0.27465 1 0.32234 1 0.95388 1 0.46589 1 NA NA 0.87318 1 RPGR 14 (2%) 758 0.86865 1 0.45697 1 1 1 1 1 0.21244 1 0.9636 1 0.85598 1 NA NA 0.67259 1 CASP8 10 (1%) 762 0.93071 1 0.57958 1 1 1 0.46662 1 0.54196 1 0.88327 1 5.5688e-05 0.0393 NA NA 0.87678 1 HLA-A 4 (1%) 768 0.21091 1 0.43607 1 1 1 0.27465 1 1 1 0.99674 1 0.58505 1 NA NA 0.91212 1 FGFR2 7 (1%) 765 0.00045699 0.321 0.75245 1 1 1 0.68418 1 0.16306 1 0.73653 1 0.047101 1 NA NA 0.61769 1 TBL1XR1 9 (1%) 763 0.56508 1 0.022449 1 1 1 0.70167 1 0.14618 1 0.27809 1 0.45371 1 NA NA 0.28298 1 PRRX1 6 (1%) 766 0.48689 1 0.90139 1 1 1 0.18116 1 1 1 0.76897 1 0.72185 1 NA NA 0.98755 1 ZNF69 5 (1%) 767 0.15592 1 0.60024 1 1 1 0.33544 1 1 1 0.65594 1 0.55977 1 NA NA 1.4537e-19 1.04e-16 GNRH2 3 (0%) 769 0.90968 1 0.17904 1 1 1 0.57306 1 0.25292 1 0.23335 1 0.43363 1 NA NA 0.99859 1 HLA-DRB1 8 (1%) 764 0.5676 1 0.0070817 1 1 1 0.68735 1 0.19842 1 3.3351e-08 2.38e-05 0.69544 1 NA NA 0.4964 1 DENND4B 8 (1%) 764 0.54574 1 0.7379 1 1 1 1 1 0.54196 1 0.99634 1 0.80643 1 NA NA 0.90249 1 CCDC66 9 (1%) 763 0.69525 1 0.75055 1 1 1 0.70167 1 0.58485 1 0.63571 1 0.77207 1 NA NA 0.5804 1 AFF2 15 (2%) 757 0.7621 1 0.037395 1 1 1 0.55163 1 1 1 0.96743 1 1.9926e-05 0.0141 NA NA 0.79448 1 HNF1A 9 (1%) 763 0.5382 1 0.20423 1 1 1 0.24661 1 0.069112 1 0.97765 1 0.6364 1 NA NA 0.95904 1 RAI1 7 (1%) 765 0.67923 1 0.9185 1 1 1 0.38219 1 1 1 0.70866 1 0.04819 1 NA NA 0.58414 1 GPS2 6 (1%) 766 0.21954 1 0.96541 1 1 1 0.65091 1 NA NA NA NA 0.63823 1 NA NA NA NA PCMTD1 3 (0%) 769 NA NA 0.52396 1 1 1 0.57306 1 1 1 0.99609 1 0.015621 1 NA NA 0.91212 1 SLC25A5 3 (0%) 769 NA NA 0.52192 1 1 1 0.57306 1 0.25292 1 0.90983 1 0.93152 1 NA NA 0.99859 1 STXBP2 9 (1%) 763 0.25073 1 0.046265 1 1 1 0.70167 1 1 1 0.99573 1 0.93479 1 NA NA 0.72019 1 FAM21A 7 (1%) 765 0.78489 1 0.42409 1 1 1 0.19995 1 1 1 0.97095 1 0.16519 1 NA NA 0.93928 1 ZNF587 9 (1%) 763 0.099445 1 0.22877 1 1 1 1 1 0.23446 1 0.98729 1 0.77411 1 NA NA 0.7313 1 POLR2J3 3 (0%) 769 0.88916 1 0.35629 1 1 1 0.57306 1 1 1 0.99884 1 0.14846 1 NA NA 0.98267 1 AXL 6 (1%) 766 0.43768 1 0.73279 1 1 1 0.34723 1 0.44269 1 0.62081 1 0.44669 1 NA NA 0.56439 1 MUC21 6 (1%) 766 0.41254 1 0.46214 1 1 1 1 1 1 1 0.99919 1 0.0026828 1 NA NA 0.42888 1 MED23 13 (2%) 759 0.42583 1 0.013147 1 1 1 0.10929 1 1 1 0.8349 1 0.16816 1 NA NA 0.188 1 KRT38 4 (1%) 768 0.49996 1 0.2415 1 1 1 0.27465 1 1 1 1.9406e-17 1.39e-14 0.053852 1 NA NA 0.87639 1 HS6ST1 5 (1%) 767 0.68847 1 0.68456 1 1 1 1 1 1 1 0.98887 1 0.013348 1 NA NA 0.97966 1 RALY 6 (1%) 766 0.72827 1 0.52326 1 1 1 1 1 0.16306 1 0.90226 1 0.43712 1 NA NA 0.73427 1 UBC 8 (1%) 764 0.21591 1 0.67222 1 1 1 1 1 1 1 0.92685 1 0.84357 1 NA NA 0.97966 1 TLR4 11 (1%) 761 0.40978 1 0.45682 1 1 1 1 1 0.58485 1 0.65096 1 0.65555 1 NA NA 0.92577 1 ODF1 5 (1%) 767 0.72189 1 0.56938 1 1 1 0.60787 1 0.080773 1 0.73062 1 0.96632 1 NA NA 0.54923 1 PABPC3 8 (1%) 764 0.30178 1 0.93958 1 0.080308 1 1 1 1 1 0.99339 1 0.16385 1 NA NA 0.80912 1 KCNT2 11 (1%) 761 0.78733 1 0.54937 1 1 1 0.30546 1 0.088529 1 0.88511 1 6.1227e-05 0.0432 NA NA 0.0086881 1 NEK5 9 (1%) 763 0.89914 1 0.1235 1 1 1 0.45981 1 1 1 0.14021 1 0.8323 1 NA NA 0.097322 1 ASPHD1 3 (0%) 769 0.044242 1 0.78184 1 1 1 0.57306 1 1 1 0.82733 1 0.72735 1 NA NA 0.94562 1 FAM47B 7 (1%) 765 0.4342 1 0.72882 1 1 1 0.38219 1 0.3854 1 0.30049 1 0.4176 1 NA NA 0.59075 1 PCDH19 14 (2%) 758 0.51737 1 0.87579 1 1 1 1 1 0.15313 1 0.81924 1 0.48175 1 NA NA 0.33383 1 ZIC3 4 (1%) 768 0.62513 1 0.86865 1 1 1 0.57732 1 1 1 0.54583 1 0.76637 1 NA NA 0.9986 1 FAM21C 6 (1%) 766 0.76776 1 0.68368 1 1 1 0.18116 1 0.3854 1 0.95277 1 0.058049 1 NA NA 0.93064 1 VSTM2B 3 (0%) 769 0.49962 1 0.33837 1 1 1 1 1 NA NA NA NA 1.549e-36 1.11e-33 NA NA NA NA SELPLG 7 (1%) 765 0.66181 1 0.26571 1 1 1 0.38219 1 0.19842 1 0.44804 1 0.00081744 0.573 NA NA 0.76061 1 SLC30A10 5 (1%) 767 0.44944 1 0.28075 1 1 1 0.33544 1 1 1 0.22862 1 0.42099 1 NA NA 0.95871 1 RGS7 8 (1%) 764 0.36512 1 0.99956 1 1 1 0.21466 1 1 1 0.83925 1 0.5942 1 NA NA 0.83676 1