Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.075 0.18 0.675 62.0 -9999.0 0.0 62.0 KIRREL -0.062 0.221 -9999.0 0.0 -0.845 62.0 62.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.076 0.18 -9999.0 0.0 -0.677 62.0 62.0 PLCG1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.055 0.137 -9999.0 0.0 -0.521 62.0 62.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.03 0.099 -9999.0 0.0 -0.38 62.0 62.0 FYN -0.05 0.131 -9999.0 0.0 -0.498 62.0 62.0 mol:Ca2+ -0.054 0.136 -9999.0 0.0 -0.516 62.0 62.0 mol:DAG -0.054 0.137 -9999.0 0.0 -0.519 62.0 62.0 NPHS2 -0.008 0.03 -9999.0 0.0 -0.273 6.0 6.0 mol:IP3 -0.054 0.137 -9999.0 0.0 -0.519 62.0 62.0 regulation of endocytosis -0.022 0.13 -9999.0 0.0 -0.465 62.0 62.0 Nephrin/NEPH1/podocin/Cholesterol -0.057 0.14 -9999.0 0.0 -0.53 62.0 62.0 establishment of cell polarity -0.075 0.18 -9999.0 0.0 -0.675 62.0 62.0 Nephrin/NEPH1/podocin/NCK1-2 -0.022 0.133 -9999.0 0.0 -0.476 62.0 62.0 Nephrin/NEPH1/beta Arrestin2 -0.022 0.132 -9999.0 0.0 -0.471 62.0 62.0 NPHS1 -0.049 0.103 -9999.0 0.0 -0.277 139.0 139.0 Nephrin/NEPH1/podocin -0.045 0.134 -9999.0 0.0 -0.501 62.0 62.0 TJP1 -0.001 0.029 -9999.0 0.0 -0.838 1.0 1.0 NCK1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.055 0.137 -9999.0 0.0 -0.521 62.0 62.0 CD2AP -0.0 0.01 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.055 0.137 -9999.0 0.0 -0.521 62.0 62.0 GRB2 -0.0 0.01 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.056 0.145 -9999.0 0.0 -0.516 68.0 68.0 cytoskeleton organization -0.04 0.125 -9999.0 0.0 -0.482 62.0 62.0 Nephrin/NEPH1 -0.054 0.136 -9999.0 0.0 -0.513 62.0 62.0 Nephrin/NEPH1/ZO-1 -0.059 0.15 -9999.0 0.0 -0.567 62.0 62.0