Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.045	0.236	0.591	2.0	-0.546	77.0	79.0
IHH	0.021	0.075	-9999.0	0.0	-0.198	1.0	1.0
SHH Np/Cholesterol/GAS1	-0.068	0.148	-9999.0	0.0	-0.314	126.0	126.0
LRPAP1	0.033	0.007	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.067	0.147	0.313	126.0	-9999.0	0.0	126.0
SMO/beta Arrestin2	-0.002	0.186	0.412	2.0	-0.474	31.0	33.0
SMO	-0.016	0.185	0.444	2.0	-0.477	35.0	37.0
AKT1	-0.021	0.191	0.307	1.0	-0.593	37.0	38.0
ARRB2	0.031	0.01	-9999.0	0.0	-9999.0	0.0	0.0
BOC	-0.091	0.238	-9999.0	0.0	-0.544	111.0	111.0
ADRBK1	0.032	0.01	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.016	0.183	0.443	2.0	-0.47	35.0	37.0
STIL	0.042	0.15	0.387	17.0	-0.341	7.0	24.0
DHH N/PTCH2	0.049	0.01	-9999.0	0.0	-9999.0	0.0	0.0
DHH N/PTCH1	0.006	0.162	0.379	2.0	-0.324	82.0	84.0
PIK3CA	0.033	0.008	-9999.0	0.0	-9999.0	0.0	0.0
DHH	0.034	0.004	-9999.0	0.0	-9999.0	0.0	0.0
PTHLH	-0.111	0.391	0.523	6.0	-0.899	94.0	100.0
determination of left/right symmetry	-0.016	0.183	0.443	2.0	-0.47	35.0	37.0
PIK3R1	-0.02	0.166	-9999.0	0.0	-0.544	47.0	47.0
skeletal system development	-0.109	0.386	0.522	6.0	-0.887	94.0	100.0
IHH N/Hhip	0.038	0.053	-9999.0	0.0	-9999.0	0.0	0.0
DHH N/Hhip	0.05	0.011	-9999.0	0.0	-9999.0	0.0	0.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.016	0.183	0.443	2.0	-0.47	35.0	37.0
pancreas development	0.034	0.011	-9999.0	0.0	-9999.0	0.0	0.0
HHAT	0.024	0.059	-9999.0	0.0	-0.544	5.0	5.0
PI3K	0.005	0.127	-9999.0	0.0	-0.4	44.0	44.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.144	0.266	-9999.0	0.0	-0.544	158.0	158.0
somite specification	-0.016	0.183	0.443	2.0	-0.47	35.0	37.0
SHH Np/Cholesterol/PTCH1	-0.01	0.121	-9999.0	0.0	-0.368	9.0	9.0
SHH Np/Cholesterol/PTCH2	0.024	0.037	-9999.0	0.0	-0.312	5.0	5.0
SHH Np/Cholesterol/Megalin	-0.056	0.145	-9999.0	0.0	-0.32	110.0	110.0
SHH	0.01	0.043	-9999.0	0.0	-0.4	5.0	5.0
catabolic process	-0.009	0.175	0.466	2.0	-0.358	86.0	88.0
SMO/Vitamin D3	0.01	0.172	0.407	16.0	-0.453	13.0	29.0
SHH Np/Cholesterol/Hhip	0.024	0.038	-9999.0	0.0	-0.312	5.0	5.0
LRP2	-0.119	0.255	-9999.0	0.0	-0.544	136.0	136.0
receptor-mediated endocytosis	-0.061	0.196	0.349	9.0	-0.509	38.0	47.0
SHH Np/Cholesterol/BOC	-0.038	0.13	-9999.0	0.0	-0.313	86.0	86.0
SHH Np/Cholesterol/CDO	0.019	0.049	-9999.0	0.0	-0.352	7.0	7.0
mesenchymal cell differentiation	-0.024	0.038	0.31	5.0	-9999.0	0.0	5.0
mol:Vitamin D3	0.027	0.159	0.412	17.0	-0.369	9.0	26.0
IHH N/PTCH2	0.038	0.052	-9999.0	0.0	-9999.0	0.0	0.0
CDON	0.027	0.045	-9999.0	0.0	-0.544	3.0	3.0
IHH N/PTCH1	-0.001	0.18	0.468	2.0	-0.361	86.0	88.0
Megalin/LRPAP1	-0.071	0.198	-9999.0	0.0	-0.395	139.0	139.0
PTCH2	0.034	0.005	-9999.0	0.0	-9999.0	0.0	0.0
SHH Np/Cholesterol	0.014	0.034	-9999.0	0.0	-0.31	5.0	5.0
PTCH1	-0.009	0.176	0.467	2.0	-0.359	86.0	88.0
HHIP	0.034	0.011	-9999.0	0.0	-9999.0	0.0	0.0