Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.494 0.261 0.629 374.0 -9999.0 0.0 374.0 KIRREL -0.049 0.078 -9999.0 0.0 -0.843 4.0 4.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.495 0.262 -9999.0 0.0 -0.63 374.0 374.0 PLCG1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.04 -9999.0 0.0 -0.865 1.0 1.0 WASL 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.541 0.314 -9999.0 0.0 -0.855 209.0 209.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.417 0.251 -9999.0 0.0 -0.667 209.0 209.0 FYN -0.509 0.305 -9999.0 0.0 -0.811 209.0 209.0 mol:Ca2+ -0.533 0.309 -9999.0 0.0 -0.841 209.0 209.0 mol:DAG -0.537 0.311 -9999.0 0.0 -0.848 209.0 209.0 NPHS2 -0.418 0.389 -9999.0 0.0 -0.82 231.0 231.0 mol:IP3 -0.537 0.311 -9999.0 0.0 -0.848 209.0 209.0 regulation of endocytosis -0.479 0.282 -9999.0 0.0 -0.762 209.0 209.0 Nephrin/NEPH1/podocin/Cholesterol -0.55 0.317 -9999.0 0.0 -0.663 398.0 398.0 establishment of cell polarity -0.494 0.261 -9999.0 0.0 -0.629 374.0 374.0 Nephrin/NEPH1/podocin/NCK1-2 -0.498 0.295 -9999.0 0.0 -0.796 209.0 209.0 Nephrin/NEPH1/beta Arrestin2 -0.488 0.289 -9999.0 0.0 -0.778 209.0 209.0 NPHS1 -0.623 0.328 -9999.0 0.0 -0.797 374.0 374.0 Nephrin/NEPH1/podocin -0.517 0.301 -9999.0 0.0 -0.819 209.0 209.0 TJP1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.541 0.314 -9999.0 0.0 -0.855 209.0 209.0 CD2AP 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.541 0.314 -9999.0 0.0 -0.855 209.0 209.0 GRB2 0.016 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.499 0.304 -9999.0 0.0 -0.801 209.0 209.0 cytoskeleton organization -0.537 0.322 -9999.0 0.0 -0.859 209.0 209.0 Nephrin/NEPH1 -0.371 0.199 -9999.0 0.0 -0.473 374.0 374.0 Nephrin/NEPH1/ZO-1 -0.402 0.216 -9999.0 0.0 -0.554 209.0 209.0