Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.394 0.231 0.525 351.0 -9999.0 0.0 351.0 KIRREL -0.053 0.057 -9999.0 0.0 -0.508 3.0 3.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.395 0.231 -9999.0 0.0 -0.526 351.0 351.0 PLCG1 0.029 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.027 0.034 -9999.0 0.0 -0.706 1.0 1.0 WASL 0.027 0.009 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.416 0.281 -9999.0 0.0 -0.538 373.0 373.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.338 0.232 -9999.0 0.0 -0.453 349.0 349.0 FYN -0.399 0.255 0.264 1.0 -0.508 373.0 374.0 mol:Ca2+ -0.408 0.277 -9999.0 0.0 -0.533 368.0 368.0 mol:DAG -0.41 0.279 -9999.0 0.0 -0.536 368.0 368.0 NPHS2 -0.341 0.328 -9999.0 0.0 -0.692 219.0 219.0 mol:IP3 -0.41 0.279 -9999.0 0.0 -0.536 368.0 368.0 regulation of endocytosis -0.372 0.25 -9999.0 0.0 -0.483 366.0 366.0 Nephrin/NEPH1/podocin/Cholesterol -0.421 0.277 -9999.0 0.0 -0.541 373.0 373.0 establishment of cell polarity -0.394 0.231 -9999.0 0.0 -0.525 351.0 351.0 Nephrin/NEPH1/podocin/NCK1-2 -0.379 0.269 -9999.0 0.0 -0.649 195.0 195.0 Nephrin/NEPH1/beta Arrestin2 -0.377 0.255 -9999.0 0.0 -0.491 366.0 366.0 NPHS1 -0.516 0.285 -9999.0 0.0 -0.67 365.0 365.0 Nephrin/NEPH1/podocin -0.397 0.264 -9999.0 0.0 -0.511 373.0 373.0 TJP1 0.029 0.003 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.029 0.005 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.412 0.281 -9999.0 0.0 -0.539 368.0 368.0 CD2AP 0.029 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.414 0.281 -9999.0 0.0 -0.538 371.0 371.0 GRB2 0.029 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.391 0.255 0.276 1.0 -0.5 372.0 373.0 cytoskeleton organization -0.431 0.285 -9999.0 0.0 -0.57 351.0 351.0 Nephrin/NEPH1 -0.286 0.172 -9999.0 0.0 -0.385 350.0 350.0 Nephrin/NEPH1/ZO-1 -0.315 0.198 -9999.0 0.0 -0.429 349.0 349.0