Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.09	0.188	0.324	6.0	-0.503	36.0	42.0
IHH	-0.013	0.128	0.294	6.0	-0.374	35.0	41.0
SHH Np/Cholesterol/GAS1	-0.036	0.057	0.116	1.0	-0.183	49.0	50.0
LRPAP1	0.021	0.004	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.036	0.057	0.182	49.0	-0.114	1.0	50.0
SMO/beta Arrestin2	-0.143	0.183	0.32	1.0	-0.326	156.0	157.0
SMO	-0.144	0.188	0.345	1.0	-0.338	154.0	155.0
AKT1	-0.078	0.145	0.266	1.0	-0.493	26.0	27.0
ARRB2	0.02	0.006	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.02	0.018	-9999.0	0.0	-0.328	1.0	1.0
ADRBK1	0.021	0.004	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.142	0.186	0.344	1.0	-0.334	154.0	155.0
STIL	-0.083	0.144	0.265	9.0	-0.314	52.0	61.0
DHH N/PTCH2	0.013	0.067	-9999.0	0.0	-0.231	27.0	27.0
DHH N/PTCH1	-0.105	0.156	-9999.0	0.0	-0.341	55.0	55.0
PIK3CA	0.021	0.004	-9999.0	0.0	-9999.0	0.0	0.0
DHH	-0.002	0.087	-9999.0	0.0	-0.328	26.0	26.0
PTHLH	-0.119	0.227	0.39	6.0	-0.554	35.0	41.0
determination of left/right symmetry	-0.142	0.186	0.344	1.0	-0.334	154.0	155.0
PIK3R1	0.021	0.005	-9999.0	0.0	-9999.0	0.0	0.0
skeletal system development	-0.118	0.226	0.389	6.0	-0.55	35.0	41.0
IHH N/Hhip	-0.222	0.179	0.212	3.0	-0.316	288.0	291.0
DHH N/Hhip	-0.121	0.143	-9999.0	0.0	-0.248	213.0	213.0
mol:Cholesterol	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.142	0.186	0.344	1.0	-0.334	154.0	155.0
pancreas development	-0.166	0.174	-9999.0	0.0	-0.328	209.0	209.0
HHAT	0.018	0.026	-9999.0	0.0	-0.328	2.0	2.0
PI3K	0.03	0.009	-9999.0	0.0	-9999.0	0.0	0.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.012	0.055	-9999.0	0.0	-0.328	10.0	10.0
somite specification	-0.142	0.186	0.344	1.0	-0.334	154.0	155.0
SHH Np/Cholesterol/PTCH1	-0.102	0.136	0.177	2.0	-0.329	55.0	57.0
SHH Np/Cholesterol/PTCH2	-0.034	0.052	0.116	1.0	-0.178	44.0	45.0
SHH Np/Cholesterol/Megalin	-0.068	0.087	0.116	1.0	-0.196	115.0	116.0
SHH	-0.039	0.069	0.156	1.0	-0.232	44.0	45.0
catabolic process	-0.106	0.164	0.234	3.0	-0.255	184.0	187.0
SMO/Vitamin D3	-0.119	0.175	0.371	2.0	-0.397	53.0	55.0
SHH Np/Cholesterol/Hhip	-0.106	0.1	0.116	1.0	-0.199	195.0	196.0
LRP2	-0.072	0.156	0.331	1.0	-0.328	105.0	106.0
receptor-mediated endocytosis	-0.164	0.186	0.304	2.0	-0.408	102.0	104.0
SHH Np/Cholesterol/BOC	-0.033	0.052	0.116	1.0	-0.178	43.0	44.0
SHH Np/Cholesterol/CDO	-0.034	0.056	0.116	1.0	-0.184	45.0	46.0
mesenchymal cell differentiation	0.105	0.1	0.198	195.0	-0.114	1.0	196.0
mol:Vitamin D3	-0.091	0.154	0.361	5.0	-0.335	53.0	58.0
IHH N/PTCH2	-0.095	0.131	0.212	4.0	-0.212	210.0	214.0
CDON	0.014	0.047	-9999.0	0.0	-0.328	7.0	7.0
IHH N/PTCH1	-0.097	0.176	0.273	3.0	-0.257	184.0	187.0
Megalin/LRPAP1	-0.037	0.116	0.238	1.0	-0.231	102.0	103.0
PTCH2	0.021	0.018	-9999.0	0.0	-0.328	1.0	1.0
SHH Np/Cholesterol	-0.029	0.052	-9999.0	0.0	-0.172	44.0	44.0
PTCH1	-0.106	0.164	0.234	3.0	-0.255	184.0	187.0
HHIP	-0.166	0.174	-9999.0	0.0	-0.328	209.0	209.0