Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.052 0.143 0.451 20.0 -9999.0 0.0 20.0 KIRREL -0.04 0.171 -9999.0 0.0 -0.62 14.0 14.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.052 0.144 -9999.0 0.0 -0.452 20.0 20.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.039 0.106 -9999.0 0.0 -0.335 14.0 14.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.004 0.089 -9999.0 0.0 -9999.0 0.0 0.0 FYN -0.021 0.104 -9999.0 0.0 -0.318 14.0 14.0 mol:Ca2+ -0.039 0.105 -9999.0 0.0 -9999.0 0.0 0.0 mol:DAG -0.039 0.106 -9999.0 0.0 -9999.0 0.0 0.0 NPHS2 -0.006 0.049 -9999.0 0.0 -0.598 1.0 1.0 mol:IP3 -0.039 0.106 -9999.0 0.0 -9999.0 0.0 0.0 regulation of endocytosis -0.024 0.095 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/Cholesterol -0.04 0.108 -9999.0 0.0 -0.334 21.0 21.0 establishment of cell polarity -0.052 0.143 -9999.0 0.0 -0.451 20.0 20.0 Nephrin/NEPH1/podocin/NCK1-2 -0.035 0.095 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/beta Arrestin2 -0.013 0.1 -9999.0 0.0 -9999.0 0.0 0.0 NPHS1 -0.019 0.11 -9999.0 0.0 -0.598 6.0 6.0 Nephrin/NEPH1/podocin -0.034 0.1 -9999.0 0.0 -0.32 14.0 14.0 TJP1 0.005 0.065 -9999.0 0.0 -0.603 2.0 2.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.039 0.106 -9999.0 0.0 -9999.0 0.0 0.0 CD2AP 0.012 0.001 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.039 0.106 -9999.0 0.0 -0.335 14.0 14.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.083 0.19 -9999.0 0.0 -0.419 35.0 35.0 cytoskeleton organization -0.004 0.105 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1 -0.037 0.103 -9999.0 0.0 -0.323 20.0 20.0 Nephrin/NEPH1/ZO-1 -0.045 0.119 -9999.0 0.0 -0.36 22.0 22.0