Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.031 0.171 0.455 1.0 -0.528 8.0 9.0 MAP3K8 0.004 0.096 -9999.0 0.0 -0.429 8.0 8.0 FOS -0.026 0.139 0.506 1.0 -0.401 11.0 12.0 PRKCA 0.013 0.064 -9999.0 0.0 -0.458 3.0 3.0 PTPN7 0.011 0.051 -9999.0 0.0 -0.243 6.0 6.0 HRAS 0.026 0.004 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.056 0.176 -9999.0 0.0 -0.458 28.0 28.0 NRAS 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.039 0.026 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.008 0.097 -9999.0 0.0 -0.411 4.0 4.0 MAP2K1 -0.06 0.201 -9999.0 0.0 -0.465 27.0 27.0 ELK1 0.02 0.02 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.049 0.172 -9999.0 0.0 -0.438 25.0 25.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.005 24.0 24.0 MAPK1 -0.009 0.094 -9999.0 0.0 -0.395 4.0 4.0 RAF1 -0.053 0.171 -9999.0 0.0 -0.419 28.0 28.0 KRAS 0.025 0.008 -9999.0 0.0 -9999.0 0.0 0.0