Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.085 0.197 0.587 23.0 -9999.0 0.0 23.0 KIRREL -0.01 0.069 -9999.0 0.0 -0.873 1.0 1.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.085 0.198 -9999.0 0.0 -0.588 23.0 23.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.127 0.2 -9999.0 0.0 -0.629 15.0 15.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.079 0.166 -9999.0 0.0 -0.569 7.0 7.0 FYN -0.105 0.198 -9999.0 0.0 -0.584 15.0 15.0 mol:Ca2+ -0.125 0.198 -9999.0 0.0 -0.622 15.0 15.0 mol:DAG -0.126 0.199 -9999.0 0.0 -0.626 15.0 15.0 NPHS2 -0.143 0.255 -9999.0 0.0 -0.584 46.0 46.0 mol:IP3 -0.126 0.199 -9999.0 0.0 -0.626 15.0 15.0 regulation of endocytosis -0.092 0.187 -9999.0 0.0 -0.548 15.0 15.0 Nephrin/NEPH1/podocin/Cholesterol -0.129 0.203 -9999.0 0.0 -0.636 15.0 15.0 establishment of cell polarity -0.085 0.197 -9999.0 0.0 -0.587 23.0 23.0 Nephrin/NEPH1/podocin/NCK1-2 -0.114 0.183 -9999.0 0.0 -0.582 15.0 15.0 Nephrin/NEPH1/beta Arrestin2 -0.092 0.19 -9999.0 0.0 -0.557 15.0 15.0 NPHS1 -0.09 0.252 -9999.0 0.0 -0.755 22.0 22.0 Nephrin/NEPH1/podocin -0.105 0.199 -9999.0 0.0 -0.589 15.0 15.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.127 0.2 -9999.0 0.0 -0.629 15.0 15.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.127 0.2 -9999.0 0.0 -0.629 15.0 15.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.099 0.196 -9999.0 0.0 -0.584 15.0 15.0 cytoskeleton organization -0.094 0.202 -9999.0 0.0 -0.712 7.0 7.0 Nephrin/NEPH1 -0.062 0.149 -9999.0 0.0 -0.516 15.0 15.0 Nephrin/NEPH1/ZO-1 -0.066 0.163 -9999.0 0.0 -0.59 13.0 13.0