Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.026 0.132 0.307 1.0 -0.528 5.0 6.0 MAP3K8 0.027 0.025 -9999.0 0.0 -0.297 1.0 1.0 FOS 0.013 0.119 0.319 1.0 -0.471 6.0 7.0 PRKCA 0.028 0.012 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 0.021 0.053 -9999.0 0.0 -0.372 3.0 3.0 HRAS 0.028 0.008 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB 0.011 0.082 -9999.0 0.0 -0.397 7.0 7.0 NRAS 0.029 0.006 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.047 0.024 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.016 0.103 -9999.0 0.0 -0.482 6.0 6.0 MAP2K1 0.008 0.087 -9999.0 0.0 -0.368 6.0 6.0 ELK1 0.028 0.012 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.008 0.07 -9999.0 0.0 -0.332 7.0 7.0 mol:GTP -0.0 0.001 -9999.0 0.0 -0.005 8.0 8.0 MAPK1 0.007 0.127 -9999.0 0.0 -0.485 10.0 10.0 RAF1 0.005 0.09 -9999.0 0.0 -0.419 7.0 7.0 KRAS 0.027 0.01 -9999.0 0.0 -9999.0 0.0 0.0