Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.164 0.304 0.693 109.0 -9999.0 0.0 109.0 KIRREL -0.067 0.233 -9999.0 0.0 -0.852 37.0 37.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.165 0.305 -9999.0 0.0 -0.694 109.0 109.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.128 0.239 -9999.0 0.0 -0.539 109.0 109.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.073 0.193 -9999.0 0.0 -0.406 109.0 109.0 FYN -0.108 0.234 -9999.0 0.0 -0.51 109.0 109.0 mol:Ca2+ -0.126 0.236 -9999.0 0.0 -0.533 109.0 109.0 mol:DAG -0.127 0.238 -9999.0 0.0 -0.536 109.0 109.0 NPHS2 -0.015 0.034 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.127 0.238 -9999.0 0.0 -0.536 109.0 109.0 regulation of endocytosis -0.113 0.212 -9999.0 0.0 -0.476 109.0 109.0 Nephrin/NEPH1/podocin/Cholesterol -0.13 0.243 -9999.0 0.0 -0.547 109.0 109.0 establishment of cell polarity -0.164 0.304 -9999.0 0.0 -0.693 109.0 109.0 Nephrin/NEPH1/podocin/NCK1-2 -0.117 0.22 -9999.0 0.0 -0.493 109.0 109.0 Nephrin/NEPH1/beta Arrestin2 -0.112 0.217 -9999.0 0.0 -0.483 109.0 109.0 NPHS1 -0.153 0.322 -9999.0 0.0 -0.832 84.0 84.0 Nephrin/NEPH1/podocin -0.122 0.228 -9999.0 0.0 -0.513 109.0 109.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.128 0.239 -9999.0 0.0 -0.539 109.0 109.0 CD2AP 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.128 0.239 -9999.0 0.0 -0.539 109.0 109.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.109 0.238 -9999.0 0.0 -0.507 113.0 113.0 cytoskeleton organization -0.098 0.253 -9999.0 0.0 -0.535 109.0 109.0 Nephrin/NEPH1 -0.126 0.236 -9999.0 0.0 -0.53 109.0 109.0 Nephrin/NEPH1/ZO-1 -0.136 0.255 -9999.0 0.0 -0.576 109.0 109.0