Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.098 0.244 0.542 100.0 -9999.0 0.0 100.0 KIRREL -0.041 0.189 -9999.0 0.0 -0.697 34.0 34.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.098 0.244 -9999.0 0.0 -0.543 100.0 100.0 PLCG1 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.053 0.202 -9999.0 0.0 -0.433 94.0 94.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.055 0.155 -9999.0 0.0 -0.348 93.0 93.0 FYN -0.061 0.193 0.266 24.0 -0.407 94.0 118.0 mol:Ca2+ -0.053 0.197 -9999.0 0.0 -0.427 93.0 93.0 mol:DAG -0.052 0.199 -9999.0 0.0 -0.43 93.0 93.0 NPHS2 -0.003 0.042 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.052 0.199 -9999.0 0.0 -0.43 93.0 93.0 regulation of endocytosis -0.047 0.178 -9999.0 0.0 -0.384 93.0 93.0 Nephrin/NEPH1/podocin/Cholesterol -0.065 0.195 -9999.0 0.0 -0.431 95.0 95.0 establishment of cell polarity -0.098 0.244 -9999.0 0.0 -0.542 100.0 100.0 Nephrin/NEPH1/podocin/NCK1-2 -0.037 0.194 -9999.0 0.0 -0.4 94.0 94.0 Nephrin/NEPH1/beta Arrestin2 -0.047 0.181 -9999.0 0.0 -0.389 93.0 93.0 NPHS1 -0.103 0.263 -9999.0 0.0 -0.678 78.0 78.0 Nephrin/NEPH1/podocin -0.058 0.187 -9999.0 0.0 -0.408 95.0 95.0 TJP1 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.052 0.2 -9999.0 0.0 -0.432 93.0 93.0 CD2AP 0.028 0.003 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.052 0.199 -9999.0 0.0 -0.432 92.0 92.0 GRB2 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.073 0.191 0.283 22.0 -0.406 96.0 118.0 cytoskeleton organization -0.08 0.195 -9999.0 0.0 -0.449 93.0 93.0 Nephrin/NEPH1 -0.069 0.183 -9999.0 0.0 -0.404 98.0 98.0 Nephrin/NEPH1/ZO-1 -0.067 0.21 -9999.0 0.0 -0.458 95.0 95.0