Correlation between copy number variation genes (focal) and selected clinical features
Uterine Corpus Endometrioid Carcinoma (Primary solid tumor)
21 April 2013  |  analyses__2013_04_21
Maintainer Information
Citation Information
doi:10.7908/C1HM56F4
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2013): Uterine Corpus Endometrioid Carcinoma (Primary solid tumor cohort) - 21 April 2013: Correlation between copy number variation genes (focal) and selected clinical features. Broad Institute of MIT and Harvard. doi:10.7908/C1HM56F4
Overview
Introduction

This pipeline computes the correlation between significant copy number variation (cnv focal) genes and selected clinical features.

Summary

Testing the association between copy number variation 98 arm-level results and 5 clinical features across 454 patients, 158 significant findings detected with Q value < 0.25.

  • Amp Peak 1(1p35.2) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 2(1p34.2) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 3(1p22.3) cnv correlated to 'AGE'.

  • Amp Peak 4(1q21.3) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 5(1q22) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 7(2p23.2) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Amp Peak 8(2q13) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 9(3p25.1) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 10(3p14.1) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Amp Peak 11(3q26.2) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 12(3q26.2) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 13(4p16.3) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 14(5p15.33) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Amp Peak 15(5q35.3) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 16(6p24.2) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 17(6q25.1) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Amp Peak 19(8p11.21) cnv correlated to 'Time to Death' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 20(8q24.21) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Amp Peak 21(8q24.21) cnv correlated to 'HISTOLOGICAL.TYPE' and 'COMPLETENESS.OF.RESECTION'.

  • Amp Peak 22(9p24.2) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Amp Peak 23(9q34.3) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 25(11p11.2) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 26(11q13.2) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Amp Peak 27(12p12.1) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Amp Peak 28(12q13.11) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Amp Peak 29(12q13.2) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Amp Peak 30(13q34) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 31(14q24.3) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 32(14q32.33) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 33(16p11.2) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 34(17q11.2) cnv correlated to 'AGE',  'HISTOLOGICAL.TYPE', and 'COMPLETENESS.OF.RESECTION'.

  • Amp Peak 35(17q12) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 36(17q25.1) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 37(18p11.31) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 38(18q11.2) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Amp Peak 39(19p13.2) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 40(19p13.11) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 41(19q12) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 42(20p13) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 43(20q11.21) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 44(20q13.12) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 45(20q13.33) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Amp Peak 46(22q12.2) cnv correlated to 'HISTOLOGICAL.TYPE' and 'COMPLETENESS.OF.RESECTION'.

  • Amp Peak 48(Xq28) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Del Peak 1(1p36.21) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 2(1p36.11) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 5(2q22.1) cnv correlated to 'Time to Death' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 7(3p14.2) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 8(3q13.31) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Del Peak 9(4p16.3) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 10(4p15.31) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 11(4q22.1) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 12(4q34.3) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 13(5q11.2) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 14(6q26) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Del Peak 15(7p22.3) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 16(7q11.22) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 17(7q31.1) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 18(7q36.3) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 19(8p23.2) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Del Peak 20(9p23) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Del Peak 21(9q34.11) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 22(10q23.31) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Del Peak 23(11p15.5) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 24(11q14.1) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 25(11q25) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 26(12q23.1) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Del Peak 27(12q24.33) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 28(13q11) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Del Peak 29(13q14.2) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 30(14q13.1) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 31(15q15.1) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 32(15q23) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 33(16p13.3) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 34(16q21) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 35(16q23.1) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 36(17p13.3) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 37(17p12) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 38(17p11.2) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 39(17q11.2) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 40(17q21.2) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 41(18q23) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Del Peak 42(19p13.3) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 43(19p12) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Del Peak 44(19q13.43) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Del Peak 45(20p12.1) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Del Peak 46(22q11.1) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 47(22q12.1) cnv correlated to 'HISTOLOGICAL.TYPE'.

  • Del Peak 48(22q13.31) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 49(22q13.32) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • Del Peak 50(Xp21.1) cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

Results
Overview of the results

Table 1.  Get Full Table Overview of the association between significant copy number variation of 98 arm-level results and 5 clinical features. Shown in the table are P values (Q values). Thresholded by Q value < 0.25, 158 significant findings detected.

Clinical
Features 		Time
to
Death 		AGE HISTOLOGICAL
TYPE 		RADIATIONS
RADIATION
REGIMENINDICATION 		COMPLETENESS
OF
RESECTION
nCNV (%) nWild-Type logrank test t-test Fisher's exact test Fisher's exact test Fisher's exact test
Amp Peak 34(17q11 2) 0 (0%) 400 0.0426
(1.00) 		0.000348
(0.118) 		1.35e-16
(6.2e-14) 		0.874
(1.00) 		0.000427
(0.144)
Amp Peak 1(1p35 2) 0 (0%) 410 0.823
(1.00) 		0.000141
(0.0492) 		2.03e-12
(8.8e-10) 		1
(1.00) 		0.876
(1.00)
Amp Peak 2(1p34 2) 0 (0%) 399 0.705
(1.00) 		3.48e-05
(0.0126) 		3.96e-17
(1.82e-14) 		0.347
(1.00) 		0.129
(1.00)
Amp Peak 4(1q21 3) 0 (0%) 253 0.133
(1.00) 		1.99e-06
(0.000766) 		0.000332
(0.114) 		0.535
(1.00) 		0.542
(1.00)
Amp Peak 5(1q22) 0 (0%) 241 0.0278
(1.00) 		9.36e-08
(3.77e-05) 		1.38e-06
(0.00053) 		0.471
(1.00) 		0.317
(1.00)
Amp Peak 8(2q13) 0 (0%) 362 0.0235
(1.00) 		0.000122
(0.0429) 		6.05e-16
(2.75e-13) 		0.799
(1.00) 		0.199
(1.00)
Amp Peak 9(3p25 1) 0 (0%) 391 0.487
(1.00) 		0.000132
(0.046) 		1.69e-09
(7.07e-07) 		0.103
(1.00) 		0.864
(1.00)
Amp Peak 11(3q26 2) 0 (0%) 320 0.19
(1.00) 		4.28e-10
(1.82e-07) 		2.49e-24
(1.2e-21) 		0.145
(1.00) 		0.199
(1.00)
Amp Peak 12(3q26 2) 0 (0%) 328 0.113
(1.00) 		7.54e-08
(3.05e-05) 		6.97e-24
(3.36e-21) 		0.169
(1.00) 		0.144
(1.00)
Amp Peak 13(4p16 3) 0 (0%) 412 0.955
(1.00) 		3.31e-07
(0.00013) 		1.57e-13
(6.9e-11) 		0.596
(1.00) 		0.594
(1.00)
Amp Peak 15(5q35 3) 0 (0%) 412 0.107
(1.00) 		0.000336
(0.115) 		8.19e-09
(3.41e-06) 		0.287
(1.00) 		0.711
(1.00)
Amp Peak 16(6p24 2) 0 (0%) 366 0.878
(1.00) 		2.81e-07
(0.00011) 		2.75e-19
(1.3e-16) 		0.241
(1.00) 		0.82
(1.00)
Amp Peak 19(8p11 21) 0 (0%) 319 1.06e-05
(0.00396) 		0.311
(1.00) 		1.04e-07
(4.14e-05) 		0.0322
(1.00) 		0.00362
(1.00)
Amp Peak 21(8q24 21) 0 (0%) 277 0.00574
(1.00) 		0.208
(1.00) 		1.64e-14
(7.3e-12) 		0.0113
(1.00) 		0.000505
(0.17)
Amp Peak 23(9q34 3) 0 (0%) 423 0.0768
(1.00) 		0.000631
(0.211) 		4.84e-07
(0.000189) 		0.689
(1.00) 		0.296
(1.00)
Amp Peak 25(11p11 2) 0 (0%) 414 0.0367
(1.00) 		5.68e-05
(0.0204) 		3.48e-09
(1.45e-06) 		0.857
(1.00) 		0.435
(1.00)
Amp Peak 30(13q34) 0 (0%) 409 0.844
(1.00) 		7.84e-07
(0.000303) 		2.62e-13
(1.15e-10) 		1
(1.00) 		0.13
(1.00)
Amp Peak 31(14q24 3) 0 (0%) 406 0.543
(1.00) 		2.48e-05
(0.00905) 		8.06e-11
(3.45e-08) 		0.184
(1.00) 		0.738
(1.00)
Amp Peak 32(14q32 33) 0 (0%) 395 0.174
(1.00) 		0.000223
(0.0771) 		7.04e-10
(2.97e-07) 		0.125
(1.00) 		0.142
(1.00)
Amp Peak 33(16p11 2) 0 (0%) 404 0.0528
(1.00) 		0.000161
(0.0559) 		5.4e-15
(2.42e-12) 		0.871
(1.00) 		0.0359
(1.00)
Amp Peak 35(17q12) 0 (0%) 397 0.0629
(1.00) 		2.18e-05
(0.00798) 		2.58e-18
(1.2e-15) 		0.757
(1.00) 		0.0855
(1.00)
Amp Peak 36(17q25 1) 0 (0%) 376 0.0618
(1.00) 		2.1e-05
(0.00771) 		3.81e-16
(1.74e-13) 		0.892
(1.00) 		0.226
(1.00)
Amp Peak 37(18p11 31) 0 (0%) 383 0.543
(1.00) 		0.000151
(0.0525) 		5.34e-20
(2.52e-17) 		0.0647
(1.00) 		0.00774
(1.00)
Amp Peak 39(19p13 2) 0 (0%) 381 0.541
(1.00) 		1.42e-11
(6.14e-09) 		2.97e-19
(1.4e-16) 		0.262
(1.00) 		0.738
(1.00)
Amp Peak 40(19p13 11) 0 (0%) 381 0.478
(1.00) 		1.13e-10
(4.83e-08) 		6.95e-22
(3.3e-19) 		0.0699
(1.00) 		0.294
(1.00)
Amp Peak 41(19q12) 0 (0%) 370 0.0024
(0.752) 		1.98e-10
(8.42e-08) 		5.57e-36
(2.72e-33) 		0.692
(1.00) 		0.234
(1.00)
Amp Peak 42(20p13) 0 (0%) 363 0.226
(1.00) 		1.07e-05
(0.00398) 		2.65e-13
(1.16e-10) 		0.248
(1.00) 		0.204
(1.00)
Amp Peak 43(20q11 21) 0 (0%) 342 0.0355
(1.00) 		2.19e-07
(8.64e-05) 		5.4e-26
(2.62e-23) 		0.057
(1.00) 		0.0623
(1.00)
Amp Peak 44(20q13 12) 0 (0%) 336 0.299
(1.00) 		3.14e-08
(1.28e-05) 		2.28e-23
(1.1e-20) 		0.0135
(1.00) 		0.0344
(1.00)
Amp Peak 45(20q13 33) 0 (0%) 338 0.327
(1.00) 		1.19e-07
(4.73e-05) 		4.59e-19
(2.14e-16) 		0.00447
(1.00) 		0.0257
(1.00)
Amp Peak 46(22q12 2) 0 (0%) 408 0.62
(1.00) 		0.00159
(0.508) 		2.87e-18
(1.33e-15) 		0.306
(1.00) 		0.00034
(0.116)
Del Peak 1(1p36 21) 0 (0%) 399 0.546
(1.00) 		6.43e-05
(0.0228) 		1.36e-08
(5.62e-06) 		0.636
(1.00) 		0.346
(1.00)
Del Peak 2(1p36 11) 0 (0%) 391 0.412
(1.00) 		1.2e-05
(0.00445) 		3.02e-13
(1.31e-10) 		0.766
(1.00) 		0.0111
(1.00)
Del Peak 5(2q22 1) 0 (0%) 416 5.01e-08
(2.03e-05) 		0.00689
(1.00) 		5.29e-07
(0.000205) 		0.0245
(1.00) 		0.00345
(1.00)
Del Peak 7(3p14 2) 0 (0%) 395 0.869
(1.00) 		2.02e-05
(0.00742) 		2.76e-15
(1.24e-12) 		0.359
(1.00) 		0.519
(1.00)
Del Peak 9(4p16 3) 0 (0%) 384 0.108
(1.00) 		9.03e-05
(0.0318) 		7.73e-15
(3.45e-12) 		0.322
(1.00) 		0.618
(1.00)
Del Peak 10(4p15 31) 0 (0%) 383 0.13
(1.00) 		3.68e-05
(0.0133) 		5.23e-14
(2.32e-11) 		0.118
(1.00) 		0.232
(1.00)
Del Peak 11(4q22 1) 0 (0%) 375 0.00625
(1.00) 		1.31e-05
(0.00487) 		2.36e-23
(1.13e-20) 		0.279
(1.00) 		0.0316
(1.00)
Del Peak 12(4q34 3) 0 (0%) 357 0.0255
(1.00) 		3.81e-06
(0.00145) 		2.5e-25
(1.21e-22) 		0.383
(1.00) 		0.0968
(1.00)
Del Peak 13(5q11 2) 0 (0%) 373 0.108
(1.00) 		4.87e-05
(0.0176) 		2.84e-22
(1.35e-19) 		0.687
(1.00) 		0.342
(1.00)
Del Peak 15(7p22 3) 0 (0%) 395 0.014
(1.00) 		5.25e-05
(0.0189) 		2.22e-13
(9.73e-11) 		0.541
(1.00) 		0.0854
(1.00)
Del Peak 16(7q11 22) 0 (0%) 422 0.564
(1.00) 		9.89e-06
(0.00371) 		9.39e-08
(3.78e-05) 		0.689
(1.00) 		0.454
(1.00)
Del Peak 17(7q31 1) 0 (0%) 414 0.716
(1.00) 		2.62e-06
(0.000999) 		5.76e-16
(2.63e-13) 		0.717
(1.00) 		0.24
(1.00)
Del Peak 18(7q36 3) 0 (0%) 404 0.622
(1.00) 		3.12e-08
(1.27e-05) 		3.54e-16
(1.62e-13) 		1
(1.00) 		0.139
(1.00)
Del Peak 21(9q34 11) 0 (0%) 350 0.223
(1.00) 		1.12e-09
(4.7e-07) 		1.16e-17
(5.37e-15) 		0.394
(1.00) 		0.311
(1.00)
Del Peak 23(11p15 5) 0 (0%) 374 0.00894
(1.00) 		2.53e-08
(1.04e-05) 		2.95e-21
(1.4e-18) 		0.0801
(1.00) 		0.0248
(1.00)
Del Peak 24(11q14 1) 0 (0%) 400 0.0579
(1.00) 		1.32e-05
(0.00489) 		2.57e-15
(1.16e-12) 		0.427
(1.00) 		0.534
(1.00)
Del Peak 25(11q25) 0 (0%) 382 0.00389
(1.00) 		8.1e-05
(0.0286) 		9.51e-16
(4.31e-13) 		0.0236
(1.00) 		0.261
(1.00)
Del Peak 27(12q24 33) 0 (0%) 407 0.109
(1.00) 		5.99e-05
(0.0213) 		1.3e-13
(5.72e-11) 		0.128
(1.00) 		0.015
(1.00)
Del Peak 29(13q14 2) 0 (0%) 380 0.0496
(1.00) 		0.000338
(0.116) 		2.96e-05
(0.0108) 		0.125
(1.00) 		0.214
(1.00)
Del Peak 30(14q13 1) 0 (0%) 398 0.00228
(0.719) 		0.00062
(0.208) 		1.43e-11
(6.15e-09) 		0.755
(1.00) 		0.881
(1.00)
Del Peak 31(15q15 1) 0 (0%) 346 0.0241
(1.00) 		1.36e-08
(5.62e-06) 		4.8e-22
(2.29e-19) 		0.0695
(1.00) 		0.0275
(1.00)
Del Peak 32(15q23) 0 (0%) 365 0.0449
(1.00) 		5.94e-06
(0.00223) 		6.56e-23
(3.14e-20) 		0.196
(1.00) 		0.439
(1.00)
Del Peak 33(16p13 3) 0 (0%) 388 0.0262
(1.00) 		2.08e-08
(8.53e-06) 		2.15e-17
(9.92e-15) 		0.56
(1.00) 		0.0176
(1.00)
Del Peak 34(16q21) 0 (0%) 332 0.033
(1.00) 		1.42e-09
(5.96e-07) 		2.86e-23
(1.37e-20) 		0.296
(1.00) 		0.129
(1.00)
Del Peak 35(16q23 1) 0 (0%) 322 0.0407
(1.00) 		1.11e-08
(4.59e-06) 		6.27e-27
(3.05e-24) 		0.428
(1.00) 		0.00536
(1.00)
Del Peak 36(17p13 3) 0 (0%) 364 0.0883
(1.00) 		5.79e-05
(0.0207) 		3.99e-19
(1.87e-16) 		0.302
(1.00) 		0.151
(1.00)
Del Peak 37(17p12) 0 (0%) 352 0.0567
(1.00) 		1.18e-07
(4.71e-05) 		3.95e-26
(1.92e-23) 		0.463
(1.00) 		0.666
(1.00)
Del Peak 38(17p11 2) 0 (0%) 361 0.0323
(1.00) 		1.35e-06
(0.000523) 		2.11e-19
(9.94e-17) 		0.445
(1.00) 		0.744
(1.00)
Del Peak 39(17q11 2) 0 (0%) 373 0.497
(1.00) 		5.19e-06
(0.00196) 		3.24e-11
(1.39e-08) 		0.139
(1.00) 		0.181
(1.00)
Del Peak 40(17q21 2) 0 (0%) 367 0.11
(1.00) 		4.94e-06
(0.00187) 		1.6e-15
(7.24e-13) 		0.152
(1.00) 		0.0717
(1.00)
Del Peak 42(19p13 3) 0 (0%) 332 0.00973
(1.00) 		5.7e-12
(2.47e-09) 		1.55e-49
(7.58e-47) 		0.296
(1.00) 		0.00413
(1.00)
Del Peak 46(22q11 1) 0 (0%) 385 0.319
(1.00) 		6.01e-05
(0.0213) 		2.23e-06
(0.000855) 		0.0152
(1.00) 		0.579
(1.00)
Del Peak 48(22q13 31) 0 (0%) 350 0.0103
(1.00) 		1.13e-08
(4.67e-06) 		5.4e-19
(2.52e-16) 		0.179
(1.00) 		0.782
(1.00)
Del Peak 49(22q13 32) 0 (0%) 345 0.0073
(1.00) 		1.62e-07
(6.42e-05) 		3.49e-19
(1.64e-16) 		0.0541
(1.00) 		0.541
(1.00)
Del Peak 50(Xp21 1) 0 (0%) 388 0.00351
(1.00) 		5.69e-05
(0.0204) 		2.97e-14
(1.32e-11) 		0.381
(1.00) 		0.102
(1.00)
Amp Peak 3(1p22 3) 0 (0%) 378 0.603
(1.00) 		0.000345
(0.117) 		0.00174
(0.551) 		1
(1.00) 		0.466
(1.00)
Amp Peak 7(2p23 2) 0 (0%) 355 0.0076
(1.00) 		0.00151
(0.482) 		1.1e-13
(4.87e-11) 		0.0461
(1.00) 		0.83
(1.00)
Amp Peak 10(3p14 1) 0 (0%) 404 0.00572
(1.00) 		0.00906
(1.00) 		0.000132
(0.046) 		0.0317
(1.00) 		0.377
(1.00)
Amp Peak 14(5p15 33) 0 (0%) 387 0.0584
(1.00) 		0.00452
(1.00) 		2.21e-16
(1.01e-13) 		0.47
(1.00) 		0.0905
(1.00)
Amp Peak 17(6q25 1) 0 (0%) 388 0.817
(1.00) 		0.00529
(1.00) 		1.79e-05
(0.0066) 		0.771
(1.00) 		0.261
(1.00)
Amp Peak 20(8q24 21) 0 (0%) 286 0.00109
(0.355) 		0.531
(1.00) 		6.02e-13
(2.62e-10) 		0.0255
(1.00) 		0.0329
(1.00)
Amp Peak 22(9p24 2) 0 (0%) 405 0.812
(1.00) 		0.00482
(1.00) 		1.28e-07
(5.07e-05) 		0.32
(1.00) 		0.445
(1.00)
Amp Peak 26(11q13 2) 0 (0%) 396 0.0893
(1.00) 		0.000754
(0.25) 		1.01e-07
(4.04e-05) 		0.76
(1.00) 		0.139
(1.00)
Amp Peak 27(12p12 1) 0 (0%) 384 0.859
(1.00) 		0.299
(1.00) 		4.45e-08
(1.81e-05) 		0.672
(1.00) 		0.295
(1.00)
Amp Peak 28(12q13 11) 0 (0%) 385 0.712
(1.00) 		0.853
(1.00) 		9.62e-08
(3.86e-05) 		0.252
(1.00) 		0.256
(1.00)
Amp Peak 29(12q13 2) 0 (0%) 378 0.995
(1.00) 		0.0485
(1.00) 		5.01e-07
(0.000195) 		0.0975
(1.00) 		0.0586
(1.00)
Amp Peak 38(18q11 2) 0 (0%) 398 0.185
(1.00) 		0.0032
(1) 		3.11e-15
(1.4e-12) 		0.532
(1.00) 		0.044
(1.00)
Amp Peak 48(Xq28) 0 (0%) 379 0.00851
(1.00) 		0.0604
(1.00) 		0.000354
(0.12) 		1
(1.00) 		0.243
(1.00)
Del Peak 8(3q13 31) 0 (0%) 432 0.76
(1.00) 		0.00168
(0.535) 		3.38e-06
(0.00128) 		0.633
(1.00) 		0.928
(1.00)
Del Peak 14(6q26) 0 (0%) 417 0.36
(1.00) 		0.00589
(1.00) 		2.21e-09
(9.26e-07) 		1
(1.00) 		0.777
(1.00)
Del Peak 19(8p23 2) 0 (0%) 367 0.319
(1.00) 		0.00094
(0.309) 		6.04e-27
(2.95e-24) 		0.516
(1.00) 		0.013
(1.00)
Del Peak 20(9p23) 0 (0%) 401 0.313
(1.00) 		0.000868
(0.287) 		3.04e-11
(1.31e-08) 		0.266
(1.00) 		0.244
(1.00)
Del Peak 22(10q23 31) 0 (0%) 398 0.101
(1.00) 		0.00351
(1.00) 		2.6e-06
(0.000992) 		0.0426
(1.00) 		0.0901
(1.00)
Del Peak 26(12q23 1) 0 (0%) 420 0.0516
(1.00) 		0.00608
(1.00) 		2.44e-10
(1.04e-07) 		0.558
(1.00) 		0.0205
(1.00)
Del Peak 28(13q11) 0 (0%) 385 0.0184
(1.00) 		0.00108
(0.355) 		4.54e-10
(1.92e-07) 		0.252
(1.00) 		0.0622
(1.00)
Del Peak 41(18q23) 0 (0%) 379 0.0102
(1.00) 		0.00109
(0.356) 		9.72e-15
(4.33e-12) 		0.00527
(1.00) 		0.00794
(1.00)
Del Peak 43(19p12) 0 (0%) 414 0.0627
(1.00) 		0.0568
(1.00) 		4.24e-08
(1.72e-05) 		0.205
(1.00) 		0.404
(1.00)
Del Peak 44(19q13 43) 0 (0%) 403 0.00131
(0.422) 		0.00117
(0.376) 		6.17e-16
(2.8e-13) 		0.871
(1.00) 		0.0278
(1.00)
Del Peak 45(20p12 1) 0 (0%) 428 0.0641
(1.00) 		0.0686
(1.00) 		0.000708
(0.236) 		0.829
(1.00) 		0.159
(1.00)
Del Peak 47(22q12 1) 0 (0%) 381 0.123
(1.00) 		0.00113
(0.368) 		4.35e-07
(0.00017) 		0.0699
(1.00) 		0.528
(1.00)
Amp Peak 6(1q42 3) 0 (0%) 266 0.307
(1.00) 		0.00125
(0.401) 		0.114
(1.00) 		0.676
(1.00) 		0.346
(1.00)
Amp Peak 18(7q22 1) 0 (0%) 382 0.00082
(0.272) 		0.0546
(1.00) 		0.0029
(0.908) 		0.16
(1.00) 		0.481
(1.00)
Amp Peak 24(10q22 2) 0 (0%) 331 0.205
(1.00) 		0.439
(1.00) 		0.0428
(1.00) 		0.644
(1.00) 		0.389
(1.00)
Amp Peak 47(Xp11 23) 0 (0%) 379 0.46
(1.00) 		0.156
(1.00) 		0.00902
(1.00) 		0.0264
(1.00) 		0.366
(1.00)
Del Peak 3(1q43) 0 (0%) 446 0.0199
(1.00) 		0.0475
(1.00) 		0.106
(1.00) 		0.112
(1.00) 		0.0338
(1.00)
Del Peak 4(2p25 3) 0 (0%) 432 0.0465
(1.00) 		0.131
(1.00) 		0.00641
(1.00) 		0.148
(1.00) 		0.201
(1.00)
Del Peak 6(2q37 3) 0 (0%) 411 0.383
(1.00) 		0.00115
(0.373) 		0.0018
(0.567) 		0.222
(1.00) 		0.038
(1.00)
'Amp Peak 1(1p35.2)' versus 'AGE'

P value = 0.000141 (t-test), Q value = 0.049

Table S1.  Gene #1: 'Amp Peak 1(1p35.2)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 1(1P35.2) CNV 44 68.9 (8.7)
AMP PEAK 1(1P35.2) WILD-TYPE 409 63.1 (11.4)

Figure S1.  Get High-res Image Gene #1: 'Amp Peak 1(1p35.2)' versus Clinical Feature #2: 'AGE'

'Amp Peak 1(1p35.2)' versus 'HISTOLOGICAL.TYPE'

P value = 2.03e-12 (Fisher's exact test), Q value = 8.8e-10

Table S2.  Gene #1: 'Amp Peak 1(1p35.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 1(1P35.2) CNV 13 4 27
AMP PEAK 1(1P35.2) WILD-TYPE 338 14 58

Figure S2.  Get High-res Image Gene #1: 'Amp Peak 1(1p35.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 2(1p34.2)' versus 'AGE'

P value = 3.48e-05 (t-test), Q value = 0.013

Table S3.  Gene #2: 'Amp Peak 2(1p34.2)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 2(1P34.2) CNV 55 69.1 (9.6)
AMP PEAK 2(1P34.2) WILD-TYPE 398 62.9 (11.3)

Figure S3.  Get High-res Image Gene #2: 'Amp Peak 2(1p34.2)' versus Clinical Feature #2: 'AGE'

'Amp Peak 2(1p34.2)' versus 'HISTOLOGICAL.TYPE'

P value = 3.96e-17 (Fisher's exact test), Q value = 1.8e-14

Table S4.  Gene #2: 'Amp Peak 2(1p34.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 2(1P34.2) CNV 15 6 34
AMP PEAK 2(1P34.2) WILD-TYPE 336 12 51

Figure S4.  Get High-res Image Gene #2: 'Amp Peak 2(1p34.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 3(1p22.3)' versus 'AGE'

P value = 0.000345 (t-test), Q value = 0.12

Table S5.  Gene #3: 'Amp Peak 3(1p22.3)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 3(1P22.3) CNV 76 67.6 (10.0)
AMP PEAK 3(1P22.3) WILD-TYPE 377 62.8 (11.3)

Figure S5.  Get High-res Image Gene #3: 'Amp Peak 3(1p22.3)' versus Clinical Feature #2: 'AGE'

'Amp Peak 4(1q21.3)' versus 'AGE'

P value = 1.99e-06 (t-test), Q value = 0.00077

Table S6.  Gene #4: 'Amp Peak 4(1q21.3)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 4(1Q21.3) CNV 201 66.4 (10.5)
AMP PEAK 4(1Q21.3) WILD-TYPE 252 61.4 (11.4)

Figure S6.  Get High-res Image Gene #4: 'Amp Peak 4(1q21.3)' versus Clinical Feature #2: 'AGE'

'Amp Peak 4(1q21.3)' versus 'HISTOLOGICAL.TYPE'

P value = 0.000332 (Fisher's exact test), Q value = 0.11

Table S7.  Gene #4: 'Amp Peak 4(1q21.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 4(1Q21.3) CNV 139 8 54
AMP PEAK 4(1Q21.3) WILD-TYPE 212 10 31

Figure S7.  Get High-res Image Gene #4: 'Amp Peak 4(1q21.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 5(1q22)' versus 'AGE'

P value = 9.36e-08 (t-test), Q value = 3.8e-05

Table S8.  Gene #5: 'Amp Peak 5(1q22)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 5(1Q22) CNV 213 66.6 (10.4)
AMP PEAK 5(1Q22) WILD-TYPE 240 61.0 (11.3)

Figure S8.  Get High-res Image Gene #5: 'Amp Peak 5(1q22)' versus Clinical Feature #2: 'AGE'

'Amp Peak 5(1q22)' versus 'HISTOLOGICAL.TYPE'

P value = 1.38e-06 (Fisher's exact test), Q value = 0.00053

Table S9.  Gene #5: 'Amp Peak 5(1q22)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 5(1Q22) CNV 144 8 61
AMP PEAK 5(1Q22) WILD-TYPE 207 10 24

Figure S9.  Get High-res Image Gene #5: 'Amp Peak 5(1q22)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 7(2p23.2)' versus 'HISTOLOGICAL.TYPE'

P value = 1.1e-13 (Fisher's exact test), Q value = 4.9e-11

Table S10.  Gene #7: 'Amp Peak 7(2p23.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 7(2P23.2) CNV 47 7 45
AMP PEAK 7(2P23.2) WILD-TYPE 304 11 40

Figure S10.  Get High-res Image Gene #7: 'Amp Peak 7(2p23.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 8(2q13)' versus 'AGE'

P value = 0.000122 (t-test), Q value = 0.043

Table S11.  Gene #8: 'Amp Peak 8(2q13)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 8(2Q13) CNV 91 67.2 (9.0)
AMP PEAK 8(2Q13) WILD-TYPE 362 62.7 (11.6)

Figure S11.  Get High-res Image Gene #8: 'Amp Peak 8(2q13)' versus Clinical Feature #2: 'AGE'

'Amp Peak 8(2q13)' versus 'HISTOLOGICAL.TYPE'

P value = 6.05e-16 (Fisher's exact test), Q value = 2.8e-13

Table S12.  Gene #8: 'Amp Peak 8(2q13)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 8(2Q13) CNV 41 4 47
AMP PEAK 8(2Q13) WILD-TYPE 310 14 38

Figure S12.  Get High-res Image Gene #8: 'Amp Peak 8(2q13)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 9(3p25.1)' versus 'AGE'

P value = 0.000132 (t-test), Q value = 0.046

Table S13.  Gene #9: 'Amp Peak 9(3p25.1)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 9(3P25.1) CNV 63 68.7 (10.8)
AMP PEAK 9(3P25.1) WILD-TYPE 390 62.8 (11.1)

Figure S13.  Get High-res Image Gene #9: 'Amp Peak 9(3p25.1)' versus Clinical Feature #2: 'AGE'

'Amp Peak 9(3p25.1)' versus 'HISTOLOGICAL.TYPE'

P value = 1.69e-09 (Fisher's exact test), Q value = 7.1e-07

Table S14.  Gene #9: 'Amp Peak 9(3p25.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 9(3P25.1) CNV 30 1 32
AMP PEAK 9(3P25.1) WILD-TYPE 321 17 53

Figure S14.  Get High-res Image Gene #9: 'Amp Peak 9(3p25.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 10(3p14.1)' versus 'HISTOLOGICAL.TYPE'

P value = 0.000132 (Fisher's exact test), Q value = 0.046

Table S15.  Gene #10: 'Amp Peak 10(3p14.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 10(3P14.1) CNV 27 2 21
AMP PEAK 10(3P14.1) WILD-TYPE 324 16 64

Figure S15.  Get High-res Image Gene #10: 'Amp Peak 10(3p14.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 11(3q26.2)' versus 'AGE'

P value = 4.28e-10 (t-test), Q value = 1.8e-07

Table S16.  Gene #11: 'Amp Peak 11(3q26.2)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 11(3Q26.2) CNV 134 68.4 (9.5)
AMP PEAK 11(3Q26.2) WILD-TYPE 319 61.7 (11.4)

Figure S16.  Get High-res Image Gene #11: 'Amp Peak 11(3q26.2)' versus Clinical Feature #2: 'AGE'

'Amp Peak 11(3q26.2)' versus 'HISTOLOGICAL.TYPE'

P value = 2.49e-24 (Fisher's exact test), Q value = 1.2e-21

Table S17.  Gene #11: 'Amp Peak 11(3q26.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 11(3Q26.2) CNV 62 7 65
AMP PEAK 11(3Q26.2) WILD-TYPE 289 11 20

Figure S17.  Get High-res Image Gene #11: 'Amp Peak 11(3q26.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 12(3q26.2)' versus 'AGE'

P value = 7.54e-08 (t-test), Q value = 3e-05

Table S18.  Gene #12: 'Amp Peak 12(3q26.2)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 12(3Q26.2) CNV 126 67.9 (9.6)
AMP PEAK 12(3Q26.2) WILD-TYPE 327 62.0 (11.4)

Figure S18.  Get High-res Image Gene #12: 'Amp Peak 12(3q26.2)' versus Clinical Feature #2: 'AGE'

'Amp Peak 12(3q26.2)' versus 'HISTOLOGICAL.TYPE'

P value = 6.97e-24 (Fisher's exact test), Q value = 3.4e-21

Table S19.  Gene #12: 'Amp Peak 12(3q26.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 12(3Q26.2) CNV 57 6 63
AMP PEAK 12(3Q26.2) WILD-TYPE 294 12 22

Figure S19.  Get High-res Image Gene #12: 'Amp Peak 12(3q26.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 13(4p16.3)' versus 'AGE'

P value = 3.31e-07 (t-test), Q value = 0.00013

Table S20.  Gene #13: 'Amp Peak 13(4p16.3)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 13(4P16.3) CNV 42 70.9 (8.2)
AMP PEAK 13(4P16.3) WILD-TYPE 411 62.9 (11.3)

Figure S20.  Get High-res Image Gene #13: 'Amp Peak 13(4p16.3)' versus Clinical Feature #2: 'AGE'

'Amp Peak 13(4p16.3)' versus 'HISTOLOGICAL.TYPE'

P value = 1.57e-13 (Fisher's exact test), Q value = 6.9e-11

Table S21.  Gene #13: 'Amp Peak 13(4p16.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 13(4P16.3) CNV 12 1 29
AMP PEAK 13(4P16.3) WILD-TYPE 339 17 56

Figure S21.  Get High-res Image Gene #13: 'Amp Peak 13(4p16.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 14(5p15.33)' versus 'HISTOLOGICAL.TYPE'

P value = 2.21e-16 (Fisher's exact test), Q value = 1e-13

Table S22.  Gene #14: 'Amp Peak 14(5p15.33)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 14(5P15.33) CNV 24 3 40
AMP PEAK 14(5P15.33) WILD-TYPE 327 15 45

Figure S22.  Get High-res Image Gene #14: 'Amp Peak 14(5p15.33)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 15(5q35.3)' versus 'AGE'

P value = 0.000336 (t-test), Q value = 0.12

Table S23.  Gene #15: 'Amp Peak 15(5q35.3)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 15(5Q35.3) CNV 42 69.7 (10.7)
AMP PEAK 15(5Q35.3) WILD-TYPE 411 63.0 (11.1)

Figure S23.  Get High-res Image Gene #15: 'Amp Peak 15(5q35.3)' versus Clinical Feature #2: 'AGE'

'Amp Peak 15(5q35.3)' versus 'HISTOLOGICAL.TYPE'

P value = 8.19e-09 (Fisher's exact test), Q value = 3.4e-06

Table S24.  Gene #15: 'Amp Peak 15(5q35.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 15(5Q35.3) CNV 16 2 24
AMP PEAK 15(5Q35.3) WILD-TYPE 335 16 61

Figure S24.  Get High-res Image Gene #15: 'Amp Peak 15(5q35.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 16(6p24.2)' versus 'AGE'

P value = 2.81e-07 (t-test), Q value = 0.00011

Table S25.  Gene #16: 'Amp Peak 16(6p24.2)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 16(6P24.2) CNV 88 68.9 (9.9)
AMP PEAK 16(6P24.2) WILD-TYPE 365 62.4 (11.2)

Figure S25.  Get High-res Image Gene #16: 'Amp Peak 16(6p24.2)' versus Clinical Feature #2: 'AGE'

'Amp Peak 16(6p24.2)' versus 'HISTOLOGICAL.TYPE'

P value = 2.75e-19 (Fisher's exact test), Q value = 1.3e-16

Table S26.  Gene #16: 'Amp Peak 16(6p24.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 16(6P24.2) CNV 35 4 49
AMP PEAK 16(6P24.2) WILD-TYPE 316 14 36

Figure S26.  Get High-res Image Gene #16: 'Amp Peak 16(6p24.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 17(6q25.1)' versus 'HISTOLOGICAL.TYPE'

P value = 1.79e-05 (Fisher's exact test), Q value = 0.0066

Table S27.  Gene #17: 'Amp Peak 17(6q25.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 17(6Q25.1) CNV 37 2 27
AMP PEAK 17(6Q25.1) WILD-TYPE 314 16 58

Figure S27.  Get High-res Image Gene #17: 'Amp Peak 17(6q25.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 19(8p11.21)' versus 'Time to Death'

P value = 1.06e-05 (logrank test), Q value = 0.004

Table S28.  Gene #19: 'Amp Peak 19(8p11.21)' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 450 42 0.0 - 187.1 (15.5)
AMP PEAK 19(8P11.21) CNV 134 23 0.0 - 113.2 (11.4)
AMP PEAK 19(8P11.21) WILD-TYPE 316 19 0.0 - 187.1 (16.8)

Figure S28.  Get High-res Image Gene #19: 'Amp Peak 19(8p11.21)' versus Clinical Feature #1: 'Time to Death'

'Amp Peak 19(8p11.21)' versus 'HISTOLOGICAL.TYPE'

P value = 1.04e-07 (Fisher's exact test), Q value = 4.1e-05

Table S29.  Gene #19: 'Amp Peak 19(8p11.21)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 19(8P11.21) CNV 82 6 47
AMP PEAK 19(8P11.21) WILD-TYPE 269 12 38

Figure S29.  Get High-res Image Gene #19: 'Amp Peak 19(8p11.21)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 20(8q24.21)' versus 'HISTOLOGICAL.TYPE'

P value = 6.02e-13 (Fisher's exact test), Q value = 2.6e-10

Table S30.  Gene #20: 'Amp Peak 20(8q24.21)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 20(8Q24.21) CNV 99 8 61
AMP PEAK 20(8Q24.21) WILD-TYPE 252 10 24

Figure S30.  Get High-res Image Gene #20: 'Amp Peak 20(8q24.21)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 21(8q24.21)' versus 'HISTOLOGICAL.TYPE'

P value = 1.64e-14 (Fisher's exact test), Q value = 7.3e-12

Table S31.  Gene #21: 'Amp Peak 21(8q24.21)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 21(8Q24.21) CNV 105 7 65
AMP PEAK 21(8Q24.21) WILD-TYPE 246 11 20

Figure S31.  Get High-res Image Gene #21: 'Amp Peak 21(8q24.21)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 21(8q24.21)' versus 'COMPLETENESS.OF.RESECTION'

P value = 0.000505 (Fisher's exact test), Q value = 0.17

Table S32.  Gene #21: 'Amp Peak 21(8q24.21)' versus Clinical Feature #5: 'COMPLETENESS.OF.RESECTION'

nPatients R0 R1 R2 RX
ALL 311 24 15 25
AMP PEAK 21(8Q24.21) CNV 119 5 13 10
AMP PEAK 21(8Q24.21) WILD-TYPE 192 19 2 15

Figure S32.  Get High-res Image Gene #21: 'Amp Peak 21(8q24.21)' versus Clinical Feature #5: 'COMPLETENESS.OF.RESECTION'

'Amp Peak 22(9p24.2)' versus 'HISTOLOGICAL.TYPE'

P value = 1.28e-07 (Fisher's exact test), Q value = 5.1e-05

Table S33.  Gene #22: 'Amp Peak 22(9p24.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 22(9P24.2) CNV 22 2 25
AMP PEAK 22(9P24.2) WILD-TYPE 329 16 60

Figure S33.  Get High-res Image Gene #22: 'Amp Peak 22(9p24.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 23(9q34.3)' versus 'AGE'

P value = 0.000631 (t-test), Q value = 0.21

Table S34.  Gene #23: 'Amp Peak 23(9q34.3)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 23(9Q34.3) CNV 31 69.0 (8.0)
AMP PEAK 23(9Q34.3) WILD-TYPE 422 63.2 (11.4)

Figure S34.  Get High-res Image Gene #23: 'Amp Peak 23(9q34.3)' versus Clinical Feature #2: 'AGE'

'Amp Peak 23(9q34.3)' versus 'HISTOLOGICAL.TYPE'

P value = 4.84e-07 (Fisher's exact test), Q value = 0.00019

Table S35.  Gene #23: 'Amp Peak 23(9q34.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 23(9Q34.3) CNV 11 4 16
AMP PEAK 23(9Q34.3) WILD-TYPE 340 14 69

Figure S35.  Get High-res Image Gene #23: 'Amp Peak 23(9q34.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 25(11p11.2)' versus 'AGE'

P value = 5.68e-05 (t-test), Q value = 0.02

Table S36.  Gene #25: 'Amp Peak 25(11p11.2)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 25(11P11.2) CNV 40 69.9 (9.3)
AMP PEAK 25(11P11.2) WILD-TYPE 413 63.0 (11.2)

Figure S36.  Get High-res Image Gene #25: 'Amp Peak 25(11p11.2)' versus Clinical Feature #2: 'AGE'

'Amp Peak 25(11p11.2)' versus 'HISTOLOGICAL.TYPE'

P value = 3.48e-09 (Fisher's exact test), Q value = 1.4e-06

Table S37.  Gene #25: 'Amp Peak 25(11p11.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 25(11P11.2) CNV 14 3 23
AMP PEAK 25(11P11.2) WILD-TYPE 337 15 62

Figure S37.  Get High-res Image Gene #25: 'Amp Peak 25(11p11.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 26(11q13.2)' versus 'HISTOLOGICAL.TYPE'

P value = 1.01e-07 (Fisher's exact test), Q value = 4e-05

Table S38.  Gene #26: 'Amp Peak 26(11q13.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 26(11Q13.2) CNV 28 2 28
AMP PEAK 26(11Q13.2) WILD-TYPE 323 16 57

Figure S38.  Get High-res Image Gene #26: 'Amp Peak 26(11q13.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 27(12p12.1)' versus 'HISTOLOGICAL.TYPE'

P value = 4.45e-08 (Fisher's exact test), Q value = 1.8e-05

Table S39.  Gene #27: 'Amp Peak 27(12p12.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 27(12P12.1) CNV 36 2 32
AMP PEAK 27(12P12.1) WILD-TYPE 315 16 53

Figure S39.  Get High-res Image Gene #27: 'Amp Peak 27(12p12.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 28(12q13.11)' versus 'HISTOLOGICAL.TYPE'

P value = 9.62e-08 (Fisher's exact test), Q value = 3.9e-05

Table S40.  Gene #28: 'Amp Peak 28(12q13.11)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 28(12Q13.11) CNV 35 3 31
AMP PEAK 28(12Q13.11) WILD-TYPE 316 15 54

Figure S40.  Get High-res Image Gene #28: 'Amp Peak 28(12q13.11)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 29(12q13.2)' versus 'HISTOLOGICAL.TYPE'

P value = 5.01e-07 (Fisher's exact test), Q value = 0.00019

Table S41.  Gene #29: 'Amp Peak 29(12q13.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 29(12Q13.2) CNV 41 3 32
AMP PEAK 29(12Q13.2) WILD-TYPE 310 15 53

Figure S41.  Get High-res Image Gene #29: 'Amp Peak 29(12q13.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 30(13q34)' versus 'AGE'

P value = 7.84e-07 (t-test), Q value = 3e-04

Table S42.  Gene #30: 'Amp Peak 30(13q34)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 30(13Q34) CNV 45 69.7 (7.4)
AMP PEAK 30(13Q34) WILD-TYPE 408 63.0 (11.4)

Figure S42.  Get High-res Image Gene #30: 'Amp Peak 30(13q34)' versus Clinical Feature #2: 'AGE'

'Amp Peak 30(13q34)' versus 'HISTOLOGICAL.TYPE'

P value = 2.62e-13 (Fisher's exact test), Q value = 1.1e-10

Table S43.  Gene #30: 'Amp Peak 30(13q34)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 30(13Q34) CNV 13 3 29
AMP PEAK 30(13Q34) WILD-TYPE 338 15 56

Figure S43.  Get High-res Image Gene #30: 'Amp Peak 30(13q34)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 31(14q24.3)' versus 'AGE'

P value = 2.48e-05 (t-test), Q value = 0.0091

Table S44.  Gene #31: 'Amp Peak 31(14q24.3)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 31(14Q24.3) CNV 48 69.0 (8.4)
AMP PEAK 31(14Q24.3) WILD-TYPE 405 63.0 (11.4)

Figure S44.  Get High-res Image Gene #31: 'Amp Peak 31(14q24.3)' versus Clinical Feature #2: 'AGE'

'Amp Peak 31(14q24.3)' versus 'HISTOLOGICAL.TYPE'

P value = 8.06e-11 (Fisher's exact test), Q value = 3.5e-08

Table S45.  Gene #31: 'Amp Peak 31(14q24.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 31(14Q24.3) CNV 17 4 27
AMP PEAK 31(14Q24.3) WILD-TYPE 334 14 58

Figure S45.  Get High-res Image Gene #31: 'Amp Peak 31(14q24.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 32(14q32.33)' versus 'AGE'

P value = 0.000223 (t-test), Q value = 0.077

Table S46.  Gene #32: 'Amp Peak 32(14q32.33)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 32(14Q32.33) CNV 59 68.2 (9.5)
AMP PEAK 32(14Q32.33) WILD-TYPE 394 63.0 (11.3)

Figure S46.  Get High-res Image Gene #32: 'Amp Peak 32(14q32.33)' versus Clinical Feature #2: 'AGE'

'Amp Peak 32(14q32.33)' versus 'HISTOLOGICAL.TYPE'

P value = 7.04e-10 (Fisher's exact test), Q value = 3e-07

Table S47.  Gene #32: 'Amp Peak 32(14q32.33)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 32(14Q32.33) CNV 25 4 30
AMP PEAK 32(14Q32.33) WILD-TYPE 326 14 55

Figure S47.  Get High-res Image Gene #32: 'Amp Peak 32(14q32.33)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 33(16p11.2)' versus 'AGE'

P value = 0.000161 (t-test), Q value = 0.056

Table S48.  Gene #33: 'Amp Peak 33(16p11.2)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 33(16P11.2) CNV 50 68.4 (8.6)
AMP PEAK 33(16P11.2) WILD-TYPE 403 63.0 (11.4)

Figure S48.  Get High-res Image Gene #33: 'Amp Peak 33(16p11.2)' versus Clinical Feature #2: 'AGE'

'Amp Peak 33(16p11.2)' versus 'HISTOLOGICAL.TYPE'

P value = 5.4e-15 (Fisher's exact test), Q value = 2.4e-12

Table S49.  Gene #33: 'Amp Peak 33(16p11.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 33(16P11.2) CNV 15 2 33
AMP PEAK 33(16P11.2) WILD-TYPE 336 16 52

Figure S49.  Get High-res Image Gene #33: 'Amp Peak 33(16p11.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 34(17q11.2)' versus 'AGE'

P value = 0.000348 (t-test), Q value = 0.12

Table S50.  Gene #34: 'Amp Peak 34(17q11.2)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 34(17Q11.2) CNV 54 67.9 (8.5)
AMP PEAK 34(17Q11.2) WILD-TYPE 399 63.1 (11.5)

Figure S50.  Get High-res Image Gene #34: 'Amp Peak 34(17q11.2)' versus Clinical Feature #2: 'AGE'

'Amp Peak 34(17q11.2)' versus 'HISTOLOGICAL.TYPE'

P value = 1.35e-16 (Fisher's exact test), Q value = 6.2e-14

Table S51.  Gene #34: 'Amp Peak 34(17q11.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 34(17Q11.2) CNV 15 5 34
AMP PEAK 34(17Q11.2) WILD-TYPE 336 13 51

Figure S51.  Get High-res Image Gene #34: 'Amp Peak 34(17q11.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 34(17q11.2)' versus 'COMPLETENESS.OF.RESECTION'

P value = 0.000427 (Fisher's exact test), Q value = 0.14

Table S52.  Gene #34: 'Amp Peak 34(17q11.2)' versus Clinical Feature #5: 'COMPLETENESS.OF.RESECTION'

nPatients R0 R1 R2 RX
ALL 311 24 15 25
AMP PEAK 34(17Q11.2) CNV 29 7 6 4
AMP PEAK 34(17Q11.2) WILD-TYPE 282 17 9 21

Figure S52.  Get High-res Image Gene #34: 'Amp Peak 34(17q11.2)' versus Clinical Feature #5: 'COMPLETENESS.OF.RESECTION'

'Amp Peak 35(17q12)' versus 'AGE'

P value = 2.18e-05 (t-test), Q value = 0.008

Table S53.  Gene #35: 'Amp Peak 35(17q12)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 35(17Q12) CNV 57 69.1 (9.4)
AMP PEAK 35(17Q12) WILD-TYPE 396 62.9 (11.3)

Figure S53.  Get High-res Image Gene #35: 'Amp Peak 35(17q12)' versus Clinical Feature #2: 'AGE'

'Amp Peak 35(17q12)' versus 'HISTOLOGICAL.TYPE'

P value = 2.58e-18 (Fisher's exact test), Q value = 1.2e-15

Table S54.  Gene #35: 'Amp Peak 35(17q12)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 35(17Q12) CNV 16 3 38
AMP PEAK 35(17Q12) WILD-TYPE 335 15 47

Figure S54.  Get High-res Image Gene #35: 'Amp Peak 35(17q12)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 36(17q25.1)' versus 'AGE'

P value = 2.1e-05 (t-test), Q value = 0.0077

Table S55.  Gene #36: 'Amp Peak 36(17q25.1)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 36(17Q25.1) CNV 78 68.0 (9.1)
AMP PEAK 36(17Q25.1) WILD-TYPE 375 62.7 (11.5)

Figure S55.  Get High-res Image Gene #36: 'Amp Peak 36(17q25.1)' versus Clinical Feature #2: 'AGE'

'Amp Peak 36(17q25.1)' versus 'HISTOLOGICAL.TYPE'

P value = 3.81e-16 (Fisher's exact test), Q value = 1.7e-13

Table S56.  Gene #36: 'Amp Peak 36(17q25.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 36(17Q25.1) CNV 30 8 40
AMP PEAK 36(17Q25.1) WILD-TYPE 321 10 45

Figure S56.  Get High-res Image Gene #36: 'Amp Peak 36(17q25.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 37(18p11.31)' versus 'AGE'

P value = 0.000151 (t-test), Q value = 0.053

Table S57.  Gene #37: 'Amp Peak 37(18p11.31)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 37(18P11.31) CNV 71 67.7 (9.2)
AMP PEAK 37(18P11.31) WILD-TYPE 382 62.9 (11.4)

Figure S57.  Get High-res Image Gene #37: 'Amp Peak 37(18p11.31)' versus Clinical Feature #2: 'AGE'

'Amp Peak 37(18p11.31)' versus 'HISTOLOGICAL.TYPE'

P value = 5.34e-20 (Fisher's exact test), Q value = 2.5e-17

Table S58.  Gene #37: 'Amp Peak 37(18p11.31)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 37(18P11.31) CNV 23 4 44
AMP PEAK 37(18P11.31) WILD-TYPE 328 14 41

Figure S58.  Get High-res Image Gene #37: 'Amp Peak 37(18p11.31)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 38(18q11.2)' versus 'HISTOLOGICAL.TYPE'

P value = 3.11e-15 (Fisher's exact test), Q value = 1.4e-12

Table S59.  Gene #38: 'Amp Peak 38(18q11.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 38(18Q11.2) CNV 18 3 35
AMP PEAK 38(18Q11.2) WILD-TYPE 333 15 50

Figure S59.  Get High-res Image Gene #38: 'Amp Peak 38(18q11.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 39(19p13.2)' versus 'AGE'

P value = 1.42e-11 (t-test), Q value = 6.1e-09

Table S60.  Gene #39: 'Amp Peak 39(19p13.2)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 39(19P13.2) CNV 73 70.7 (8.4)
AMP PEAK 39(19P13.2) WILD-TYPE 380 62.3 (11.2)

Figure S60.  Get High-res Image Gene #39: 'Amp Peak 39(19p13.2)' versus Clinical Feature #2: 'AGE'

'Amp Peak 39(19p13.2)' versus 'HISTOLOGICAL.TYPE'

P value = 2.97e-19 (Fisher's exact test), Q value = 1.4e-16

Table S61.  Gene #39: 'Amp Peak 39(19p13.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 39(19P13.2) CNV 24 7 42
AMP PEAK 39(19P13.2) WILD-TYPE 327 11 43

Figure S61.  Get High-res Image Gene #39: 'Amp Peak 39(19p13.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 40(19p13.11)' versus 'AGE'

P value = 1.13e-10 (t-test), Q value = 4.8e-08

Table S62.  Gene #40: 'Amp Peak 40(19p13.11)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 40(19P13.11) CNV 73 70.7 (9.0)
AMP PEAK 40(19P13.11) WILD-TYPE 380 62.3 (11.1)

Figure S62.  Get High-res Image Gene #40: 'Amp Peak 40(19p13.11)' versus Clinical Feature #2: 'AGE'

'Amp Peak 40(19p13.11)' versus 'HISTOLOGICAL.TYPE'

P value = 6.95e-22 (Fisher's exact test), Q value = 3.3e-19

Table S63.  Gene #40: 'Amp Peak 40(19p13.11)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 40(19P13.11) CNV 22 6 45
AMP PEAK 40(19P13.11) WILD-TYPE 329 12 40

Figure S63.  Get High-res Image Gene #40: 'Amp Peak 40(19p13.11)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 41(19q12)' versus 'AGE'

P value = 1.98e-10 (t-test), Q value = 8.4e-08

Table S64.  Gene #41: 'Amp Peak 41(19q12)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 41(19Q12) CNV 84 69.5 (8.1)
AMP PEAK 41(19Q12) WILD-TYPE 369 62.3 (11.4)

Figure S64.  Get High-res Image Gene #41: 'Amp Peak 41(19q12)' versus Clinical Feature #2: 'AGE'

'Amp Peak 41(19q12)' versus 'HISTOLOGICAL.TYPE'

P value = 5.57e-36 (Fisher's exact test), Q value = 2.7e-33

Table S65.  Gene #41: 'Amp Peak 41(19q12)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 41(19Q12) CNV 18 9 57
AMP PEAK 41(19Q12) WILD-TYPE 333 9 28

Figure S65.  Get High-res Image Gene #41: 'Amp Peak 41(19q12)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 42(20p13)' versus 'AGE'

P value = 1.07e-05 (t-test), Q value = 0.004

Table S66.  Gene #42: 'Amp Peak 42(20p13)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 42(20P13) CNV 91 68.4 (11.1)
AMP PEAK 42(20P13) WILD-TYPE 362 62.4 (11.0)

Figure S66.  Get High-res Image Gene #42: 'Amp Peak 42(20p13)' versus Clinical Feature #2: 'AGE'

'Amp Peak 42(20p13)' versus 'HISTOLOGICAL.TYPE'

P value = 2.65e-13 (Fisher's exact test), Q value = 1.2e-10

Table S67.  Gene #42: 'Amp Peak 42(20p13)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 42(20P13) CNV 43 4 44
AMP PEAK 42(20P13) WILD-TYPE 308 14 41

Figure S67.  Get High-res Image Gene #42: 'Amp Peak 42(20p13)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 43(20q11.21)' versus 'AGE'

P value = 2.19e-07 (t-test), Q value = 8.6e-05

Table S68.  Gene #43: 'Amp Peak 43(20q11.21)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 43(20Q11.21) CNV 112 68.2 (9.9)
AMP PEAK 43(20Q11.21) WILD-TYPE 341 62.2 (11.3)

Figure S68.  Get High-res Image Gene #43: 'Amp Peak 43(20q11.21)' versus Clinical Feature #2: 'AGE'

'Amp Peak 43(20q11.21)' versus 'HISTOLOGICAL.TYPE'

P value = 5.4e-26 (Fisher's exact test), Q value = 2.6e-23

Table S69.  Gene #43: 'Amp Peak 43(20q11.21)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 43(20Q11.21) CNV 45 6 61
AMP PEAK 43(20Q11.21) WILD-TYPE 306 12 24

Figure S69.  Get High-res Image Gene #43: 'Amp Peak 43(20q11.21)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 44(20q13.12)' versus 'AGE'

P value = 3.14e-08 (t-test), Q value = 1.3e-05

Table S70.  Gene #44: 'Amp Peak 44(20q13.12)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 44(20Q13.12) CNV 118 68.4 (10.3)
AMP PEAK 44(20Q13.12) WILD-TYPE 335 62.0 (11.1)

Figure S70.  Get High-res Image Gene #44: 'Amp Peak 44(20q13.12)' versus Clinical Feature #2: 'AGE'

'Amp Peak 44(20q13.12)' versus 'HISTOLOGICAL.TYPE'

P value = 2.28e-23 (Fisher's exact test), Q value = 1.1e-20

Table S71.  Gene #44: 'Amp Peak 44(20q13.12)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 44(20Q13.12) CNV 51 7 60
AMP PEAK 44(20Q13.12) WILD-TYPE 300 11 25

Figure S71.  Get High-res Image Gene #44: 'Amp Peak 44(20q13.12)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 45(20q13.33)' versus 'AGE'

P value = 1.19e-07 (t-test), Q value = 4.7e-05

Table S72.  Gene #45: 'Amp Peak 45(20q13.33)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
AMP PEAK 45(20Q13.33) CNV 116 68.3 (10.4)
AMP PEAK 45(20Q13.33) WILD-TYPE 337 62.0 (11.1)

Figure S72.  Get High-res Image Gene #45: 'Amp Peak 45(20q13.33)' versus Clinical Feature #2: 'AGE'

'Amp Peak 45(20q13.33)' versus 'HISTOLOGICAL.TYPE'

P value = 4.59e-19 (Fisher's exact test), Q value = 2.1e-16

Table S73.  Gene #45: 'Amp Peak 45(20q13.33)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 45(20Q13.33) CNV 54 6 56
AMP PEAK 45(20Q13.33) WILD-TYPE 297 12 29

Figure S73.  Get High-res Image Gene #45: 'Amp Peak 45(20q13.33)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 46(22q12.2)' versus 'HISTOLOGICAL.TYPE'

P value = 2.87e-18 (Fisher's exact test), Q value = 1.3e-15

Table S74.  Gene #46: 'Amp Peak 46(22q12.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 46(22Q12.2) CNV 10 2 34
AMP PEAK 46(22Q12.2) WILD-TYPE 341 16 51

Figure S74.  Get High-res Image Gene #46: 'Amp Peak 46(22q12.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Amp Peak 46(22q12.2)' versus 'COMPLETENESS.OF.RESECTION'

P value = 0.00034 (Fisher's exact test), Q value = 0.12

Table S75.  Gene #46: 'Amp Peak 46(22q12.2)' versus Clinical Feature #5: 'COMPLETENESS.OF.RESECTION'

nPatients R0 R1 R2 RX
ALL 311 24 15 25
AMP PEAK 46(22Q12.2) CNV 24 2 7 4
AMP PEAK 46(22Q12.2) WILD-TYPE 287 22 8 21

Figure S75.  Get High-res Image Gene #46: 'Amp Peak 46(22q12.2)' versus Clinical Feature #5: 'COMPLETENESS.OF.RESECTION'

'Amp Peak 48(Xq28)' versus 'HISTOLOGICAL.TYPE'

P value = 0.000354 (Fisher's exact test), Q value = 0.12

Table S76.  Gene #48: 'Amp Peak 48(Xq28)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
AMP PEAK 48(XQ28) CNV 46 2 27
AMP PEAK 48(XQ28) WILD-TYPE 305 16 58

Figure S76.  Get High-res Image Gene #48: 'Amp Peak 48(Xq28)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 1(1p36.21)' versus 'AGE'

P value = 6.43e-05 (t-test), Q value = 0.023

Table S77.  Gene #49: 'Del Peak 1(1p36.21)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 1(1P36.21) CNV 55 69.3 (10.4)
DEL PEAK 1(1P36.21) WILD-TYPE 398 62.9 (11.2)

Figure S77.  Get High-res Image Gene #49: 'Del Peak 1(1p36.21)' versus Clinical Feature #2: 'AGE'

'Del Peak 1(1p36.21)' versus 'HISTOLOGICAL.TYPE'

P value = 1.36e-08 (Fisher's exact test), Q value = 5.6e-06

Table S78.  Gene #49: 'Del Peak 1(1p36.21)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 1(1P36.21) CNV 24 4 27
DEL PEAK 1(1P36.21) WILD-TYPE 327 14 58

Figure S78.  Get High-res Image Gene #49: 'Del Peak 1(1p36.21)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 2(1p36.11)' versus 'AGE'

P value = 1.2e-05 (t-test), Q value = 0.0045

Table S79.  Gene #50: 'Del Peak 2(1p36.11)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 2(1P36.11) CNV 63 69.0 (9.7)
DEL PEAK 2(1P36.11) WILD-TYPE 390 62.8 (11.2)

Figure S79.  Get High-res Image Gene #50: 'Del Peak 2(1p36.11)' versus Clinical Feature #2: 'AGE'

'Del Peak 2(1p36.11)' versus 'HISTOLOGICAL.TYPE'

P value = 3.02e-13 (Fisher's exact test), Q value = 1.3e-10

Table S80.  Gene #50: 'Del Peak 2(1p36.11)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 2(1P36.11) CNV 24 4 35
DEL PEAK 2(1P36.11) WILD-TYPE 327 14 50

Figure S80.  Get High-res Image Gene #50: 'Del Peak 2(1p36.11)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 5(2q22.1)' versus 'Time to Death'

P value = 5.01e-08 (logrank test), Q value = 2e-05

Table S81.  Gene #53: 'Del Peak 5(2q22.1)' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 450 42 0.0 - 187.1 (15.5)
DEL PEAK 5(2Q22.1) CNV 38 11 0.1 - 113.2 (7.4)
DEL PEAK 5(2Q22.1) WILD-TYPE 412 31 0.0 - 187.1 (16.6)

Figure S81.  Get High-res Image Gene #53: 'Del Peak 5(2q22.1)' versus Clinical Feature #1: 'Time to Death'

'Del Peak 5(2q22.1)' versus 'HISTOLOGICAL.TYPE'

P value = 5.29e-07 (Fisher's exact test), Q value = 0.00021

Table S82.  Gene #53: 'Del Peak 5(2q22.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 5(2Q22.1) CNV 16 1 21
DEL PEAK 5(2Q22.1) WILD-TYPE 335 17 64

Figure S82.  Get High-res Image Gene #53: 'Del Peak 5(2q22.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 7(3p14.2)' versus 'AGE'

P value = 2.02e-05 (t-test), Q value = 0.0074

Table S83.  Gene #55: 'Del Peak 7(3p14.2)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 7(3P14.2) CNV 59 68.0 (7.4)
DEL PEAK 7(3P14.2) WILD-TYPE 394 63.0 (11.6)

Figure S83.  Get High-res Image Gene #55: 'Del Peak 7(3p14.2)' versus Clinical Feature #2: 'AGE'

'Del Peak 7(3p14.2)' versus 'HISTOLOGICAL.TYPE'

P value = 2.76e-15 (Fisher's exact test), Q value = 1.2e-12

Table S84.  Gene #55: 'Del Peak 7(3p14.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 7(3P14.2) CNV 19 6 34
DEL PEAK 7(3P14.2) WILD-TYPE 332 12 51

Figure S84.  Get High-res Image Gene #55: 'Del Peak 7(3p14.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 8(3q13.31)' versus 'HISTOLOGICAL.TYPE'

P value = 3.38e-06 (Fisher's exact test), Q value = 0.0013

Table S85.  Gene #56: 'Del Peak 8(3q13.31)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 8(3Q13.31) CNV 7 1 14
DEL PEAK 8(3Q13.31) WILD-TYPE 344 17 71

Figure S85.  Get High-res Image Gene #56: 'Del Peak 8(3q13.31)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 9(4p16.3)' versus 'AGE'

P value = 9.03e-05 (t-test), Q value = 0.032

Table S86.  Gene #57: 'Del Peak 9(4p16.3)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 9(4P16.3) CNV 70 67.9 (9.3)
DEL PEAK 9(4P16.3) WILD-TYPE 383 62.9 (11.4)

Figure S86.  Get High-res Image Gene #57: 'Del Peak 9(4p16.3)' versus Clinical Feature #2: 'AGE'

'Del Peak 9(4p16.3)' versus 'HISTOLOGICAL.TYPE'

P value = 7.73e-15 (Fisher's exact test), Q value = 3.5e-12

Table S87.  Gene #57: 'Del Peak 9(4p16.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 9(4P16.3) CNV 27 4 39
DEL PEAK 9(4P16.3) WILD-TYPE 324 14 46

Figure S87.  Get High-res Image Gene #57: 'Del Peak 9(4p16.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 10(4p15.31)' versus 'AGE'

P value = 3.68e-05 (t-test), Q value = 0.013

Table S88.  Gene #58: 'Del Peak 10(4p15.31)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 10(4P15.31) CNV 71 68.2 (9.5)
DEL PEAK 10(4P15.31) WILD-TYPE 382 62.8 (11.3)

Figure S88.  Get High-res Image Gene #58: 'Del Peak 10(4p15.31)' versus Clinical Feature #2: 'AGE'

'Del Peak 10(4p15.31)' versus 'HISTOLOGICAL.TYPE'

P value = 5.23e-14 (Fisher's exact test), Q value = 2.3e-11

Table S89.  Gene #58: 'Del Peak 10(4p15.31)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 10(4P15.31) CNV 29 3 39
DEL PEAK 10(4P15.31) WILD-TYPE 322 15 46

Figure S89.  Get High-res Image Gene #58: 'Del Peak 10(4p15.31)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 11(4q22.1)' versus 'AGE'

P value = 1.31e-05 (t-test), Q value = 0.0049

Table S90.  Gene #59: 'Del Peak 11(4q22.1)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 11(4Q22.1) CNV 79 68.1 (9.1)
DEL PEAK 11(4Q22.1) WILD-TYPE 374 62.7 (11.4)

Figure S90.  Get High-res Image Gene #59: 'Del Peak 11(4q22.1)' versus Clinical Feature #2: 'AGE'

'Del Peak 11(4q22.1)' versus 'HISTOLOGICAL.TYPE'

P value = 2.36e-23 (Fisher's exact test), Q value = 1.1e-20

Table S91.  Gene #59: 'Del Peak 11(4q22.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 11(4Q22.1) CNV 25 5 49
DEL PEAK 11(4Q22.1) WILD-TYPE 326 13 36

Figure S91.  Get High-res Image Gene #59: 'Del Peak 11(4q22.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 12(4q34.3)' versus 'AGE'

P value = 3.81e-06 (t-test), Q value = 0.0014

Table S92.  Gene #60: 'Del Peak 12(4q34.3)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 12(4Q34.3) CNV 97 68.0 (9.9)
DEL PEAK 12(4Q34.3) WILD-TYPE 356 62.4 (11.3)

Figure S92.  Get High-res Image Gene #60: 'Del Peak 12(4q34.3)' versus Clinical Feature #2: 'AGE'

'Del Peak 12(4q34.3)' versus 'HISTOLOGICAL.TYPE'

P value = 2.5e-25 (Fisher's exact test), Q value = 1.2e-22

Table S93.  Gene #60: 'Del Peak 12(4q34.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 12(4Q34.3) CNV 35 6 56
DEL PEAK 12(4Q34.3) WILD-TYPE 316 12 29

Figure S93.  Get High-res Image Gene #60: 'Del Peak 12(4q34.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 13(5q11.2)' versus 'AGE'

P value = 4.87e-05 (t-test), Q value = 0.018

Table S94.  Gene #61: 'Del Peak 13(5q11.2)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 13(5Q11.2) CNV 81 67.9 (9.8)
DEL PEAK 13(5Q11.2) WILD-TYPE 372 62.7 (11.3)

Figure S94.  Get High-res Image Gene #61: 'Del Peak 13(5q11.2)' versus Clinical Feature #2: 'AGE'

'Del Peak 13(5q11.2)' versus 'HISTOLOGICAL.TYPE'

P value = 2.84e-22 (Fisher's exact test), Q value = 1.4e-19

Table S95.  Gene #61: 'Del Peak 13(5q11.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 13(5Q11.2) CNV 29 2 50
DEL PEAK 13(5Q11.2) WILD-TYPE 322 16 35

Figure S95.  Get High-res Image Gene #61: 'Del Peak 13(5q11.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 14(6q26)' versus 'HISTOLOGICAL.TYPE'

P value = 2.21e-09 (Fisher's exact test), Q value = 9.3e-07

Table S96.  Gene #62: 'Del Peak 14(6q26)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 14(6Q26) CNV 12 3 22
DEL PEAK 14(6Q26) WILD-TYPE 339 15 63

Figure S96.  Get High-res Image Gene #62: 'Del Peak 14(6q26)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 15(7p22.3)' versus 'AGE'

P value = 5.25e-05 (t-test), Q value = 0.019

Table S97.  Gene #63: 'Del Peak 15(7p22.3)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 15(7P22.3) CNV 58 68.7 (9.5)
DEL PEAK 15(7P22.3) WILD-TYPE 395 62.9 (11.3)

Figure S97.  Get High-res Image Gene #63: 'Del Peak 15(7p22.3)' versus Clinical Feature #2: 'AGE'

'Del Peak 15(7p22.3)' versus 'HISTOLOGICAL.TYPE'

P value = 2.22e-13 (Fisher's exact test), Q value = 9.7e-11

Table S98.  Gene #63: 'Del Peak 15(7p22.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 15(7P22.3) CNV 21 5 33
DEL PEAK 15(7P22.3) WILD-TYPE 330 13 52

Figure S98.  Get High-res Image Gene #63: 'Del Peak 15(7p22.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 16(7q11.22)' versus 'AGE'

P value = 9.89e-06 (t-test), Q value = 0.0037

Table S99.  Gene #64: 'Del Peak 16(7q11.22)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 16(7Q11.22) CNV 32 71.2 (8.5)
DEL PEAK 16(7Q11.22) WILD-TYPE 421 63.1 (11.2)

Figure S99.  Get High-res Image Gene #64: 'Del Peak 16(7q11.22)' versus Clinical Feature #2: 'AGE'

'Del Peak 16(7q11.22)' versus 'HISTOLOGICAL.TYPE'

P value = 9.39e-08 (Fisher's exact test), Q value = 3.8e-05

Table S100.  Gene #64: 'Del Peak 16(7q11.22)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 16(7Q11.22) CNV 11 2 19
DEL PEAK 16(7Q11.22) WILD-TYPE 340 16 66

Figure S100.  Get High-res Image Gene #64: 'Del Peak 16(7q11.22)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 17(7q31.1)' versus 'AGE'

P value = 2.62e-06 (t-test), Q value = 0.001

Table S101.  Gene #65: 'Del Peak 17(7q31.1)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 17(7Q31.1) CNV 40 69.9 (7.5)
DEL PEAK 17(7Q31.1) WILD-TYPE 413 63.0 (11.4)

Figure S101.  Get High-res Image Gene #65: 'Del Peak 17(7q31.1)' versus Clinical Feature #2: 'AGE'

'Del Peak 17(7q31.1)' versus 'HISTOLOGICAL.TYPE'

P value = 5.76e-16 (Fisher's exact test), Q value = 2.6e-13

Table S102.  Gene #65: 'Del Peak 17(7q31.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 17(7Q31.1) CNV 8 3 29
DEL PEAK 17(7Q31.1) WILD-TYPE 343 15 56

Figure S102.  Get High-res Image Gene #65: 'Del Peak 17(7q31.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 18(7q36.3)' versus 'AGE'

P value = 3.12e-08 (t-test), Q value = 1.3e-05

Table S103.  Gene #66: 'Del Peak 18(7q36.3)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 18(7Q36.3) CNV 50 70.8 (8.3)
DEL PEAK 18(7Q36.3) WILD-TYPE 403 62.7 (11.3)

Figure S103.  Get High-res Image Gene #66: 'Del Peak 18(7q36.3)' versus Clinical Feature #2: 'AGE'

'Del Peak 18(7q36.3)' versus 'HISTOLOGICAL.TYPE'

P value = 3.54e-16 (Fisher's exact test), Q value = 1.6e-13

Table S104.  Gene #66: 'Del Peak 18(7q36.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 18(7Q36.3) CNV 13 5 32
DEL PEAK 18(7Q36.3) WILD-TYPE 338 13 53

Figure S104.  Get High-res Image Gene #66: 'Del Peak 18(7q36.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 19(8p23.2)' versus 'HISTOLOGICAL.TYPE'

P value = 6.04e-27 (Fisher's exact test), Q value = 2.9e-24

Table S105.  Gene #67: 'Del Peak 19(8p23.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 19(8P23.2) CNV 28 4 55
DEL PEAK 19(8P23.2) WILD-TYPE 323 14 30

Figure S105.  Get High-res Image Gene #67: 'Del Peak 19(8p23.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 20(9p23)' versus 'HISTOLOGICAL.TYPE'

P value = 3.04e-11 (Fisher's exact test), Q value = 1.3e-08

Table S106.  Gene #68: 'Del Peak 20(9p23)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 20(9P23) CNV 20 3 30
DEL PEAK 20(9P23) WILD-TYPE 331 15 55

Figure S106.  Get High-res Image Gene #68: 'Del Peak 20(9p23)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 21(9q34.11)' versus 'AGE'

P value = 1.12e-09 (t-test), Q value = 4.7e-07

Table S107.  Gene #69: 'Del Peak 21(9q34.11)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 21(9Q34.11) CNV 104 68.8 (8.8)
DEL PEAK 21(9Q34.11) WILD-TYPE 349 62.1 (11.4)

Figure S107.  Get High-res Image Gene #69: 'Del Peak 21(9q34.11)' versus Clinical Feature #2: 'AGE'

'Del Peak 21(9q34.11)' versus 'HISTOLOGICAL.TYPE'

P value = 1.16e-17 (Fisher's exact test), Q value = 5.4e-15

Table S108.  Gene #69: 'Del Peak 21(9q34.11)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 21(9Q34.11) CNV 46 8 50
DEL PEAK 21(9Q34.11) WILD-TYPE 305 10 35

Figure S108.  Get High-res Image Gene #69: 'Del Peak 21(9q34.11)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 22(10q23.31)' versus 'HISTOLOGICAL.TYPE'

P value = 2.6e-06 (Fisher's exact test), Q value = 0.00099

Table S109.  Gene #70: 'Del Peak 22(10q23.31)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 22(10Q23.31) CNV 28 3 25
DEL PEAK 22(10Q23.31) WILD-TYPE 323 15 60

Figure S109.  Get High-res Image Gene #70: 'Del Peak 22(10q23.31)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 23(11p15.5)' versus 'AGE'

P value = 2.53e-08 (t-test), Q value = 1e-05

Table S110.  Gene #71: 'Del Peak 23(11p15.5)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 23(11P15.5) CNV 80 69.3 (9.0)
DEL PEAK 23(11P15.5) WILD-TYPE 373 62.4 (11.3)

Figure S110.  Get High-res Image Gene #71: 'Del Peak 23(11p15.5)' versus Clinical Feature #2: 'AGE'

'Del Peak 23(11p15.5)' versus 'HISTOLOGICAL.TYPE'

P value = 2.95e-21 (Fisher's exact test), Q value = 1.4e-18

Table S111.  Gene #71: 'Del Peak 23(11p15.5)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 23(11P15.5) CNV 27 6 47
DEL PEAK 23(11P15.5) WILD-TYPE 324 12 38

Figure S111.  Get High-res Image Gene #71: 'Del Peak 23(11p15.5)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 24(11q14.1)' versus 'AGE'

P value = 1.32e-05 (t-test), Q value = 0.0049

Table S112.  Gene #72: 'Del Peak 24(11q14.1)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 24(11Q14.1) CNV 54 69.1 (8.8)
DEL PEAK 24(11Q14.1) WILD-TYPE 399 62.9 (11.4)

Figure S112.  Get High-res Image Gene #72: 'Del Peak 24(11q14.1)' versus Clinical Feature #2: 'AGE'

'Del Peak 24(11q14.1)' versus 'HISTOLOGICAL.TYPE'

P value = 2.57e-15 (Fisher's exact test), Q value = 1.2e-12

Table S113.  Gene #72: 'Del Peak 24(11q14.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 24(11Q14.1) CNV 16 6 32
DEL PEAK 24(11Q14.1) WILD-TYPE 335 12 53

Figure S113.  Get High-res Image Gene #72: 'Del Peak 24(11q14.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 25(11q25)' versus 'AGE'

P value = 8.1e-05 (t-test), Q value = 0.029

Table S114.  Gene #73: 'Del Peak 25(11q25)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 25(11Q25) CNV 72 68.2 (10.0)
DEL PEAK 25(11Q25) WILD-TYPE 381 62.8 (11.3)

Figure S114.  Get High-res Image Gene #73: 'Del Peak 25(11q25)' versus Clinical Feature #2: 'AGE'

'Del Peak 25(11q25)' versus 'HISTOLOGICAL.TYPE'

P value = 9.51e-16 (Fisher's exact test), Q value = 4.3e-13

Table S115.  Gene #73: 'Del Peak 25(11q25)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 25(11Q25) CNV 27 5 40
DEL PEAK 25(11Q25) WILD-TYPE 324 13 45

Figure S115.  Get High-res Image Gene #73: 'Del Peak 25(11q25)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 26(12q23.1)' versus 'HISTOLOGICAL.TYPE'

P value = 2.44e-10 (Fisher's exact test), Q value = 1e-07

Table S116.  Gene #74: 'Del Peak 26(12q23.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 26(12Q23.1) CNV 10 1 23
DEL PEAK 26(12Q23.1) WILD-TYPE 341 17 62

Figure S116.  Get High-res Image Gene #74: 'Del Peak 26(12q23.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 27(12q24.33)' versus 'AGE'

P value = 5.99e-05 (t-test), Q value = 0.021

Table S117.  Gene #75: 'Del Peak 27(12q24.33)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 27(12Q24.33) CNV 47 69.1 (8.9)
DEL PEAK 27(12Q24.33) WILD-TYPE 406 63.0 (11.3)

Figure S117.  Get High-res Image Gene #75: 'Del Peak 27(12q24.33)' versus Clinical Feature #2: 'AGE'

'Del Peak 27(12q24.33)' versus 'HISTOLOGICAL.TYPE'

P value = 1.3e-13 (Fisher's exact test), Q value = 5.7e-11

Table S118.  Gene #75: 'Del Peak 27(12q24.33)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 27(12Q24.33) CNV 15 1 31
DEL PEAK 27(12Q24.33) WILD-TYPE 336 17 54

Figure S118.  Get High-res Image Gene #75: 'Del Peak 27(12q24.33)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 28(13q11)' versus 'HISTOLOGICAL.TYPE'

P value = 4.54e-10 (Fisher's exact test), Q value = 1.9e-07

Table S119.  Gene #76: 'Del Peak 28(13q11)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 28(13Q11) CNV 32 3 34
DEL PEAK 28(13Q11) WILD-TYPE 319 15 51

Figure S119.  Get High-res Image Gene #76: 'Del Peak 28(13q11)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 29(13q14.2)' versus 'AGE'

P value = 0.000338 (t-test), Q value = 0.12

Table S120.  Gene #77: 'Del Peak 29(13q14.2)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 29(13Q14.2) CNV 74 67.5 (9.6)
DEL PEAK 29(13Q14.2) WILD-TYPE 379 62.9 (11.4)

Figure S120.  Get High-res Image Gene #77: 'Del Peak 29(13q14.2)' versus Clinical Feature #2: 'AGE'

'Del Peak 29(13q14.2)' versus 'HISTOLOGICAL.TYPE'

P value = 2.96e-05 (Fisher's exact test), Q value = 0.011

Table S121.  Gene #77: 'Del Peak 29(13q14.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 29(13Q14.2) CNV 42 4 28
DEL PEAK 29(13Q14.2) WILD-TYPE 309 14 57

Figure S121.  Get High-res Image Gene #77: 'Del Peak 29(13q14.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 30(14q13.1)' versus 'AGE'

P value = 0.00062 (t-test), Q value = 0.21

Table S122.  Gene #78: 'Del Peak 30(14q13.1)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 30(14Q13.1) CNV 56 68.1 (9.9)
DEL PEAK 30(14Q13.1) WILD-TYPE 397 63.0 (11.3)

Figure S122.  Get High-res Image Gene #78: 'Del Peak 30(14q13.1)' versus Clinical Feature #2: 'AGE'

'Del Peak 30(14q13.1)' versus 'HISTOLOGICAL.TYPE'

P value = 1.43e-11 (Fisher's exact test), Q value = 6.1e-09

Table S123.  Gene #78: 'Del Peak 30(14q13.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 30(14Q13.1) CNV 21 5 30
DEL PEAK 30(14Q13.1) WILD-TYPE 330 13 55

Figure S123.  Get High-res Image Gene #78: 'Del Peak 30(14q13.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 31(15q15.1)' versus 'AGE'

P value = 1.36e-08 (t-test), Q value = 5.6e-06

Table S124.  Gene #79: 'Del Peak 31(15q15.1)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 31(15Q15.1) CNV 108 68.6 (9.6)
DEL PEAK 31(15Q15.1) WILD-TYPE 345 62.1 (11.3)

Figure S124.  Get High-res Image Gene #79: 'Del Peak 31(15q15.1)' versus Clinical Feature #2: 'AGE'

'Del Peak 31(15q15.1)' versus 'HISTOLOGICAL.TYPE'

P value = 4.8e-22 (Fisher's exact test), Q value = 2.3e-19

Table S125.  Gene #79: 'Del Peak 31(15q15.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 31(15Q15.1) CNV 45 7 56
DEL PEAK 31(15Q15.1) WILD-TYPE 306 11 29

Figure S125.  Get High-res Image Gene #79: 'Del Peak 31(15q15.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 32(15q23)' versus 'AGE'

P value = 5.94e-06 (t-test), Q value = 0.0022

Table S126.  Gene #80: 'Del Peak 32(15q23)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 32(15Q23) CNV 89 68.0 (9.5)
DEL PEAK 32(15Q23) WILD-TYPE 364 62.6 (11.4)

Figure S126.  Get High-res Image Gene #80: 'Del Peak 32(15q23)' versus Clinical Feature #2: 'AGE'

'Del Peak 32(15q23)' versus 'HISTOLOGICAL.TYPE'

P value = 6.56e-23 (Fisher's exact test), Q value = 3.1e-20

Table S127.  Gene #80: 'Del Peak 32(15q23)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 32(15Q23) CNV 32 5 52
DEL PEAK 32(15Q23) WILD-TYPE 319 13 33

Figure S127.  Get High-res Image Gene #80: 'Del Peak 32(15q23)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 33(16p13.3)' versus 'AGE'

P value = 2.08e-08 (t-test), Q value = 8.5e-06

Table S128.  Gene #81: 'Del Peak 33(16p13.3)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 33(16P13.3) CNV 66 69.5 (8.0)
DEL PEAK 33(16P13.3) WILD-TYPE 387 62.6 (11.4)

Figure S128.  Get High-res Image Gene #81: 'Del Peak 33(16p13.3)' versus Clinical Feature #2: 'AGE'

'Del Peak 33(16p13.3)' versus 'HISTOLOGICAL.TYPE'

P value = 2.15e-17 (Fisher's exact test), Q value = 9.9e-15

Table S129.  Gene #81: 'Del Peak 33(16p13.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 33(16P13.3) CNV 22 4 40
DEL PEAK 33(16P13.3) WILD-TYPE 329 14 45

Figure S129.  Get High-res Image Gene #81: 'Del Peak 33(16p13.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 34(16q21)' versus 'AGE'

P value = 1.42e-09 (t-test), Q value = 6e-07

Table S130.  Gene #82: 'Del Peak 34(16q21)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 34(16Q21) CNV 122 68.4 (9.1)
DEL PEAK 34(16Q21) WILD-TYPE 331 61.9 (11.5)

Figure S130.  Get High-res Image Gene #82: 'Del Peak 34(16q21)' versus Clinical Feature #2: 'AGE'

'Del Peak 34(16q21)' versus 'HISTOLOGICAL.TYPE'

P value = 2.86e-23 (Fisher's exact test), Q value = 1.4e-20

Table S131.  Gene #82: 'Del Peak 34(16q21)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 34(16Q21) CNV 54 7 61
DEL PEAK 34(16Q21) WILD-TYPE 297 11 24

Figure S131.  Get High-res Image Gene #82: 'Del Peak 34(16q21)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 35(16q23.1)' versus 'AGE'

P value = 1.11e-08 (t-test), Q value = 4.6e-06

Table S132.  Gene #83: 'Del Peak 35(16q23.1)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 35(16Q23.1) CNV 132 68.0 (9.4)
DEL PEAK 35(16Q23.1) WILD-TYPE 321 61.9 (11.5)

Figure S132.  Get High-res Image Gene #83: 'Del Peak 35(16q23.1)' versus Clinical Feature #2: 'AGE'

'Del Peak 35(16q23.1)' versus 'HISTOLOGICAL.TYPE'

P value = 6.27e-27 (Fisher's exact test), Q value = 3.1e-24

Table S133.  Gene #83: 'Del Peak 35(16q23.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 35(16Q23.1) CNV 59 6 67
DEL PEAK 35(16Q23.1) WILD-TYPE 292 12 18

Figure S133.  Get High-res Image Gene #83: 'Del Peak 35(16q23.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 36(17p13.3)' versus 'AGE'

P value = 5.79e-05 (t-test), Q value = 0.021

Table S134.  Gene #84: 'Del Peak 36(17p13.3)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 36(17P13.3) CNV 90 67.4 (9.1)
DEL PEAK 36(17P13.3) WILD-TYPE 363 62.7 (11.5)

Figure S134.  Get High-res Image Gene #84: 'Del Peak 36(17p13.3)' versus Clinical Feature #2: 'AGE'

'Del Peak 36(17p13.3)' versus 'HISTOLOGICAL.TYPE'

P value = 3.99e-19 (Fisher's exact test), Q value = 1.9e-16

Table S135.  Gene #84: 'Del Peak 36(17p13.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 36(17P13.3) CNV 35 8 47
DEL PEAK 36(17P13.3) WILD-TYPE 316 10 38

Figure S135.  Get High-res Image Gene #84: 'Del Peak 36(17p13.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 37(17p12)' versus 'AGE'

P value = 1.18e-07 (t-test), Q value = 4.7e-05

Table S136.  Gene #85: 'Del Peak 37(17p12)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 37(17P12) CNV 102 68.2 (9.0)
DEL PEAK 37(17P12) WILD-TYPE 351 62.3 (11.5)

Figure S136.  Get High-res Image Gene #85: 'Del Peak 37(17p12)' versus Clinical Feature #2: 'AGE'

'Del Peak 37(17p12)' versus 'HISTOLOGICAL.TYPE'

P value = 3.95e-26 (Fisher's exact test), Q value = 1.9e-23

Table S137.  Gene #85: 'Del Peak 37(17p12)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 37(17P12) CNV 37 8 57
DEL PEAK 37(17P12) WILD-TYPE 314 10 28

Figure S137.  Get High-res Image Gene #85: 'Del Peak 37(17p12)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 38(17p11.2)' versus 'AGE'

P value = 1.35e-06 (t-test), Q value = 0.00052

Table S138.  Gene #86: 'Del Peak 38(17p11.2)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 38(17P11.2) CNV 93 68.1 (9.1)
DEL PEAK 38(17P11.2) WILD-TYPE 360 62.5 (11.5)

Figure S138.  Get High-res Image Gene #86: 'Del Peak 38(17p11.2)' versus Clinical Feature #2: 'AGE'

'Del Peak 38(17p11.2)' versus 'HISTOLOGICAL.TYPE'

P value = 2.11e-19 (Fisher's exact test), Q value = 9.9e-17

Table S139.  Gene #86: 'Del Peak 38(17p11.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 38(17P11.2) CNV 37 7 49
DEL PEAK 38(17P11.2) WILD-TYPE 314 11 36

Figure S139.  Get High-res Image Gene #86: 'Del Peak 38(17p11.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 39(17q11.2)' versus 'AGE'

P value = 5.19e-06 (t-test), Q value = 0.002

Table S140.  Gene #87: 'Del Peak 39(17q11.2)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 39(17Q11.2) CNV 81 68.2 (9.2)
DEL PEAK 39(17Q11.2) WILD-TYPE 372 62.6 (11.4)

Figure S140.  Get High-res Image Gene #87: 'Del Peak 39(17q11.2)' versus Clinical Feature #2: 'AGE'

'Del Peak 39(17q11.2)' versus 'HISTOLOGICAL.TYPE'

P value = 3.24e-11 (Fisher's exact test), Q value = 1.4e-08

Table S141.  Gene #87: 'Del Peak 39(17q11.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 39(17Q11.2) CNV 38 5 38
DEL PEAK 39(17Q11.2) WILD-TYPE 313 13 47

Figure S141.  Get High-res Image Gene #87: 'Del Peak 39(17q11.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 40(17q21.2)' versus 'AGE'

P value = 4.94e-06 (t-test), Q value = 0.0019

Table S142.  Gene #88: 'Del Peak 40(17q21.2)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 40(17Q21.2) CNV 87 68.1 (9.5)
DEL PEAK 40(17Q21.2) WILD-TYPE 366 62.6 (11.4)

Figure S142.  Get High-res Image Gene #88: 'Del Peak 40(17q21.2)' versus Clinical Feature #2: 'AGE'

'Del Peak 40(17q21.2)' versus 'HISTOLOGICAL.TYPE'

P value = 1.6e-15 (Fisher's exact test), Q value = 7.2e-13

Table S143.  Gene #88: 'Del Peak 40(17q21.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 40(17Q21.2) CNV 37 6 44
DEL PEAK 40(17Q21.2) WILD-TYPE 314 12 41

Figure S143.  Get High-res Image Gene #88: 'Del Peak 40(17q21.2)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 41(18q23)' versus 'HISTOLOGICAL.TYPE'

P value = 9.72e-15 (Fisher's exact test), Q value = 4.3e-12

Table S144.  Gene #89: 'Del Peak 41(18q23)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 41(18Q23) CNV 30 5 40
DEL PEAK 41(18Q23) WILD-TYPE 321 13 45

Figure S144.  Get High-res Image Gene #89: 'Del Peak 41(18q23)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 42(19p13.3)' versus 'AGE'

P value = 5.7e-12 (t-test), Q value = 2.5e-09

Table S145.  Gene #90: 'Del Peak 42(19p13.3)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 42(19P13.3) CNV 122 68.9 (8.7)
DEL PEAK 42(19P13.3) WILD-TYPE 331 61.7 (11.5)

Figure S145.  Get High-res Image Gene #90: 'Del Peak 42(19p13.3)' versus Clinical Feature #2: 'AGE'

'Del Peak 42(19p13.3)' versus 'HISTOLOGICAL.TYPE'

P value = 1.55e-49 (Fisher's exact test), Q value = 7.6e-47

Table S146.  Gene #90: 'Del Peak 42(19p13.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 42(19P13.3) CNV 36 8 78
DEL PEAK 42(19P13.3) WILD-TYPE 315 10 7

Figure S146.  Get High-res Image Gene #90: 'Del Peak 42(19p13.3)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 43(19p12)' versus 'HISTOLOGICAL.TYPE'

P value = 4.24e-08 (Fisher's exact test), Q value = 1.7e-05

Table S147.  Gene #91: 'Del Peak 43(19p12)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 43(19P12) CNV 15 4 21
DEL PEAK 43(19P12) WILD-TYPE 336 14 64

Figure S147.  Get High-res Image Gene #91: 'Del Peak 43(19p12)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 44(19q13.43)' versus 'HISTOLOGICAL.TYPE'

P value = 6.17e-16 (Fisher's exact test), Q value = 2.8e-13

Table S148.  Gene #92: 'Del Peak 44(19q13.43)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 44(19Q13.43) CNV 14 4 33
DEL PEAK 44(19Q13.43) WILD-TYPE 337 14 52

Figure S148.  Get High-res Image Gene #92: 'Del Peak 44(19q13.43)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 45(20p12.1)' versus 'HISTOLOGICAL.TYPE'

P value = 0.000708 (Fisher's exact test), Q value = 0.24

Table S149.  Gene #93: 'Del Peak 45(20p12.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 45(20P12.1) CNV 12 2 12
DEL PEAK 45(20P12.1) WILD-TYPE 339 16 73

Figure S149.  Get High-res Image Gene #93: 'Del Peak 45(20p12.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 46(22q11.1)' versus 'AGE'

P value = 6.01e-05 (t-test), Q value = 0.021

Table S150.  Gene #94: 'Del Peak 46(22q11.1)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 46(22Q11.1) CNV 69 67.9 (8.8)
DEL PEAK 46(22Q11.1) WILD-TYPE 384 62.9 (11.5)

Figure S150.  Get High-res Image Gene #94: 'Del Peak 46(22q11.1)' versus Clinical Feature #2: 'AGE'

'Del Peak 46(22q11.1)' versus 'HISTOLOGICAL.TYPE'

P value = 2.23e-06 (Fisher's exact test), Q value = 0.00086

Table S151.  Gene #94: 'Del Peak 46(22q11.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 46(22Q11.1) CNV 37 3 29
DEL PEAK 46(22Q11.1) WILD-TYPE 314 15 56

Figure S151.  Get High-res Image Gene #94: 'Del Peak 46(22q11.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 47(22q12.1)' versus 'HISTOLOGICAL.TYPE'

P value = 4.35e-07 (Fisher's exact test), Q value = 0.00017

Table S152.  Gene #95: 'Del Peak 47(22q12.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 47(22Q12.1) CNV 38 7 28
DEL PEAK 47(22Q12.1) WILD-TYPE 313 11 57

Figure S152.  Get High-res Image Gene #95: 'Del Peak 47(22q12.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 48(22q13.31)' versus 'AGE'

P value = 1.13e-08 (t-test), Q value = 4.7e-06

Table S153.  Gene #96: 'Del Peak 48(22q13.31)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 48(22Q13.31) CNV 104 68.7 (9.4)
DEL PEAK 48(22Q13.31) WILD-TYPE 349 62.1 (11.3)

Figure S153.  Get High-res Image Gene #96: 'Del Peak 48(22q13.31)' versus Clinical Feature #2: 'AGE'

'Del Peak 48(22q13.31)' versus 'HISTOLOGICAL.TYPE'

P value = 5.4e-19 (Fisher's exact test), Q value = 2.5e-16

Table S154.  Gene #96: 'Del Peak 48(22q13.31)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 48(22Q13.31) CNV 45 7 52
DEL PEAK 48(22Q13.31) WILD-TYPE 306 11 33

Figure S154.  Get High-res Image Gene #96: 'Del Peak 48(22q13.31)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 49(22q13.32)' versus 'AGE'

P value = 1.62e-07 (t-test), Q value = 6.4e-05

Table S155.  Gene #97: 'Del Peak 49(22q13.32)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 49(22Q13.32) CNV 109 68.3 (10.0)
DEL PEAK 49(22Q13.32) WILD-TYPE 344 62.2 (11.2)

Figure S155.  Get High-res Image Gene #97: 'Del Peak 49(22q13.32)' versus Clinical Feature #2: 'AGE'

'Del Peak 49(22q13.32)' versus 'HISTOLOGICAL.TYPE'

P value = 3.49e-19 (Fisher's exact test), Q value = 1.6e-16

Table S156.  Gene #97: 'Del Peak 49(22q13.32)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 49(22Q13.32) CNV 48 8 53
DEL PEAK 49(22Q13.32) WILD-TYPE 303 10 32

Figure S156.  Get High-res Image Gene #97: 'Del Peak 49(22q13.32)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'Del Peak 50(Xp21.1)' versus 'AGE'

P value = 5.69e-05 (t-test), Q value = 0.02

Table S157.  Gene #98: 'Del Peak 50(Xp21.1)' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 453 63.6 (11.2)
DEL PEAK 50(XP21.1) CNV 66 68.1 (8.9)
DEL PEAK 50(XP21.1) WILD-TYPE 387 62.9 (11.4)

Figure S157.  Get High-res Image Gene #98: 'Del Peak 50(Xp21.1)' versus Clinical Feature #2: 'AGE'

'Del Peak 50(Xp21.1)' versus 'HISTOLOGICAL.TYPE'

P value = 2.97e-14 (Fisher's exact test), Q value = 1.3e-11

Table S158.  Gene #98: 'Del Peak 50(Xp21.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 351 18 85
DEL PEAK 50(XP21.1) CNV 26 2 38
DEL PEAK 50(XP21.1) WILD-TYPE 325 16 47

Figure S158.  Get High-res Image Gene #98: 'Del Peak 50(Xp21.1)' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

Methods & Data
Input

  • Mutation data file = all_lesions.conf_99.cnv.cluster.txt

  • Clinical data file = UCEC-TP.clin.merged.picked.txt

  • Number of patients = 454

  • Number of significantly arm-level cnvs = 98

  • Number of selected clinical features = 5

  • Exclude genes that fewer than K tumors have mutations, K = 3

Survival analysis

For survival clinical features, the Kaplan-Meier survival curves of tumors with and without gene mutations were plotted and the statistical significance P values were estimated by logrank test (Bland and Altman 2004) using the 'survdiff' function in R

Student's t-test analysis

For continuous numerical clinical features, two-tailed Student's t test with unequal variance (Lehmann and Romano 2005) was applied to compare the clinical values between tumors with and without gene mutations using 't.test' function in R

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

Download Results

This is an experimental feature. The full results of the analysis summarized in this report can be downloaded from the TCGA Data Coordination Center.

References
[1] Bland and Altman, Statistics notes: The logrank test, BMJ 328(7447):1073 (2004)
[2] Lehmann and Romano, Testing Statistical Hypotheses (3E ed.), New York: Springer. ISBN 0387988645 (2005)
[3] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)
[4] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)
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