Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.043 0.138 0.359 58.0 -9999.0 0.0 58.0 KIRREL -0.047 0.165 -9999.0 0.0 -0.512 41.0 41.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.043 0.138 -9999.0 0.0 -0.359 58.0 58.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.032 0.12 -9999.0 0.0 -0.315 40.0 40.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.008 0.084 -9999.0 0.0 -0.254 27.0 27.0 FYN -0.024 0.097 -9999.0 0.0 -0.288 30.0 30.0 mol:Ca2+ -0.023 0.104 -9999.0 0.0 -0.296 30.0 30.0 mol:DAG -0.022 0.104 -9999.0 0.0 -0.297 30.0 30.0 NPHS2 -0.008 0.045 -9999.0 0.0 -0.46 3.0 3.0 mol:IP3 -0.022 0.104 -9999.0 0.0 -0.297 30.0 30.0 regulation of endocytosis -0.015 0.092 -9999.0 0.0 -0.265 30.0 30.0 Nephrin/NEPH1/podocin/Cholesterol -0.03 0.104 -9999.0 0.0 -0.261 60.0 60.0 establishment of cell polarity -0.043 0.138 -9999.0 0.0 -0.359 58.0 58.0 Nephrin/NEPH1/podocin/NCK1-2 -0.013 0.097 -9999.0 0.0 -0.354 5.0 5.0 Nephrin/NEPH1/beta Arrestin2 -0.014 0.094 -9999.0 0.0 -0.268 30.0 30.0 NPHS1 -0.019 0.102 -9999.0 0.0 -0.454 19.0 19.0 Nephrin/NEPH1/podocin -0.024 0.098 -9999.0 0.0 -0.289 30.0 30.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.011 0.029 -9999.0 0.0 -0.538 1.0 1.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.022 0.105 -9999.0 0.0 -0.298 30.0 30.0 CD2AP -0.004 0.093 -9999.0 0.0 -0.538 11.0 11.0 Nephrin/NEPH1/podocin/GRB2 -0.022 0.105 -9999.0 0.0 -0.298 30.0 30.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.046 0.122 -9999.0 0.0 -0.275 64.0 64.0 cytoskeleton organization -0.009 0.096 -9999.0 0.0 -0.299 12.0 12.0 Nephrin/NEPH1 -0.028 0.097 -9999.0 0.0 -0.25 58.0 58.0 Nephrin/NEPH1/ZO-1 -0.025 0.111 -9999.0 0.0 -0.277 58.0 58.0