Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.01 0.102 0.365 9.0 -9999.0 0.0 9.0 KIRREL -0.006 0.126 -9999.0 0.0 -0.494 9.0 9.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.01 0.102 -9999.0 0.0 -0.365 9.0 9.0 PLCG1 0.025 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.024 0.009 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.025 0.107 -9999.0 0.0 -0.273 15.0 15.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.004 0.083 -9999.0 0.0 -0.253 14.0 14.0 FYN -0.008 0.11 0.29 6.0 -0.257 15.0 21.0 mol:Ca2+ 0.023 0.102 -9999.0 0.0 -0.27 14.0 14.0 mol:DAG 0.024 0.103 -9999.0 0.0 -0.271 14.0 14.0 NPHS2 -0.019 0.111 -9999.0 0.0 -0.488 7.0 7.0 mol:IP3 0.024 0.103 -9999.0 0.0 -0.271 14.0 14.0 regulation of endocytosis 0.015 0.091 -9999.0 0.0 -0.238 15.0 15.0 Nephrin/NEPH1/podocin/Cholesterol 0.013 0.1 -9999.0 0.0 -0.269 15.0 15.0 establishment of cell polarity 0.01 0.102 -9999.0 0.0 -0.365 9.0 9.0 Nephrin/NEPH1/podocin/NCK1-2 0.034 0.104 -9999.0 0.0 -0.25 15.0 15.0 Nephrin/NEPH1/beta Arrestin2 0.017 0.093 -9999.0 0.0 -0.24 15.0 15.0 NPHS1 0.006 0.045 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin 0.013 0.096 -9999.0 0.0 -0.258 15.0 15.0 TJP1 0.026 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.025 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.025 0.104 -9999.0 0.0 -0.272 14.0 14.0 CD2AP 0.027 0.002 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.027 0.104 -9999.0 0.0 -0.272 14.0 14.0 GRB2 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.007 0.109 0.264 8.0 -0.246 15.0 23.0 cytoskeleton organization -0.018 0.088 0.193 2.0 -0.282 13.0 15.0 Nephrin/NEPH1 0.013 0.073 -9999.0 0.0 -0.254 9.0 9.0 Nephrin/NEPH1/ZO-1 0.025 0.088 -9999.0 0.0 -0.291 9.0 9.0