Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.081 0.186 0.663 76.0 -9999.0 0.0 76.0 KIRREL -0.069 0.23 -9999.0 0.0 -0.832 76.0 76.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.081 0.186 -9999.0 0.0 -0.664 76.0 76.0 PLCG1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.058 0.142 -9999.0 0.0 -0.51 76.0 76.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.034 0.103 -9999.0 0.0 -0.374 76.0 76.0 FYN -0.054 0.135 -9999.0 0.0 -0.486 76.0 76.0 mol:Ca2+ -0.058 0.14 -9999.0 0.0 -0.505 76.0 76.0 mol:DAG -0.058 0.141 -9999.0 0.0 -0.508 76.0 76.0 NPHS2 -0.008 0.029 -9999.0 0.0 -0.275 5.0 5.0 mol:IP3 -0.058 0.141 -9999.0 0.0 -0.508 76.0 76.0 regulation of endocytosis -0.026 0.133 -9999.0 0.0 -0.454 76.0 76.0 Nephrin/NEPH1/podocin/Cholesterol -0.061 0.144 -9999.0 0.0 -0.518 76.0 76.0 establishment of cell polarity -0.081 0.186 -9999.0 0.0 -0.663 76.0 76.0 Nephrin/NEPH1/podocin/NCK1-2 -0.026 0.137 -9999.0 0.0 -0.465 76.0 76.0 Nephrin/NEPH1/beta Arrestin2 -0.026 0.135 -9999.0 0.0 -0.46 76.0 76.0 NPHS1 -0.05 0.103 -9999.0 0.0 -0.278 150.0 150.0 Nephrin/NEPH1/podocin -0.049 0.138 -9999.0 0.0 -0.489 76.0 76.0 TJP1 -0.001 0.027 -9999.0 0.0 -0.825 1.0 1.0 NCK1 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.058 0.142 -9999.0 0.0 -0.51 76.0 76.0 CD2AP -0.0 0.009 -9999.0 0.0 -0.279 1.0 1.0 Nephrin/NEPH1/podocin/GRB2 -0.058 0.142 -9999.0 0.0 -0.51 76.0 76.0 GRB2 -0.0 0.009 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.061 0.152 -9999.0 0.0 -0.512 83.0 83.0 cytoskeleton organization -0.044 0.13 -9999.0 0.0 -0.472 76.0 76.0 Nephrin/NEPH1 -0.058 0.14 -9999.0 0.0 -0.502 76.0 76.0 Nephrin/NEPH1/ZO-1 -0.064 0.155 -9999.0 0.0 -0.553 76.0 76.0