Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.044	0.228	0.423	4.0	-0.653	94.0	98.0
IHH	0.015	0.082	0.27	25.0	-0.241	5.0	30.0
SHH Np/Cholesterol/GAS1	-0.0	0.078	-9999.0	0.0	-0.343	41.0	41.0
LRPAP1	0.023	0.005	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.0	0.077	0.341	41.0	-9999.0	0.0	41.0
SMO/beta Arrestin2	-0.02	0.209	-9999.0	0.0	-0.624	80.0	80.0
SMO	-0.044	0.211	-9999.0	0.0	-0.646	83.0	83.0
AKT1	-0.002	0.123	-9999.0	0.0	-0.524	20.0	20.0
ARRB2	0.022	0.007	-9999.0	0.0	-9999.0	0.0	0.0
BOC	-0.02	0.158	-9999.0	0.0	-0.59	64.0	64.0
ADRBK1	0.022	0.006	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.043	0.207	-9999.0	0.0	-0.634	83.0	83.0
STIL	0.007	0.178	0.299	28.0	-0.484	75.0	103.0
DHH N/PTCH2	-0.016	0.152	-9999.0	0.0	-0.448	95.0	95.0
DHH N/PTCH1	-0.03	0.206	0.291	1.0	-0.51	121.0	122.0
PIK3CA	0.023	0.005	-9999.0	0.0	-9999.0	0.0	0.0
DHH	0.007	0.101	0.265	1.0	-0.59	25.0	26.0
PTHLH	-0.065	0.304	0.436	10.0	-0.853	99.0	109.0
determination of left/right symmetry	-0.043	0.207	-9999.0	0.0	-0.634	83.0	83.0
PIK3R1	0.022	0.021	-9999.0	0.0	-0.59	1.0	1.0
skeletal system development	-0.064	0.299	0.436	10.0	-0.839	99.0	109.0
IHH N/Hhip	0.027	0.055	-9999.0	0.0	-0.479	1.0	1.0
DHH N/Hhip	0.021	0.08	-9999.0	0.0	-0.423	27.0	27.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.043	0.207	-9999.0	0.0	-0.634	83.0	83.0
pancreas development	0.024	0.03	0.265	7.0	-0.589	1.0	8.0
HHAT	0.019	0.022	-9999.0	0.0	-0.59	1.0	1.0
PI3K	0.032	0.019	-9999.0	0.0	-0.439	1.0	1.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.008	0.137	-9999.0	0.0	-0.59	47.0	47.0
somite specification	-0.043	0.207	-9999.0	0.0	-0.634	83.0	83.0
SHH Np/Cholesterol/PTCH1	-0.027	0.163	0.264	4.0	-0.502	78.0	82.0
SHH Np/Cholesterol/PTCH2	-0.009	0.093	-9999.0	0.0	-0.346	58.0	58.0
SHH Np/Cholesterol/Megalin	-0.061	0.152	0.282	3.0	-0.346	183.0	186.0
SHH	-0.001	0.038	0.361	5.0	-0.443	1.0	6.0
catabolic process	-0.034	0.208	0.313	2.0	-0.568	105.0	107.0
SMO/Vitamin D3	-0.01	0.2	0.344	17.0	-0.574	76.0	93.0
SHH Np/Cholesterol/Hhip	0.016	0.032	0.286	5.0	-0.351	2.0	7.0
LRP2	-0.124	0.271	0.265	22.0	-0.59	224.0	246.0
receptor-mediated endocytosis	-0.081	0.225	0.306	8.0	-0.612	94.0	102.0
SHH Np/Cholesterol/BOC	-0.006	0.089	-9999.0	0.0	-0.345	54.0	54.0
SHH Np/Cholesterol/CDO	0.012	0.043	-9999.0	0.0	-0.348	11.0	11.0
mesenchymal cell differentiation	-0.016	0.031	0.348	2.0	-0.283	5.0	7.0
mol:Vitamin D3	0.002	0.185	0.347	17.0	-0.504	78.0	95.0
IHH N/PTCH2	-0.014	0.148	-9999.0	0.0	-0.476	75.0	75.0
CDON	0.014	0.068	-9999.0	0.0	-0.59	11.0	11.0
IHH N/PTCH1	-0.025	0.214	0.356	3.0	-0.572	105.0	108.0
Megalin/LRPAP1	-0.081	0.208	-9999.0	0.0	-0.438	224.0	224.0
PTCH2	-0.026	0.167	-9999.0	0.0	-0.59	72.0	72.0
SHH Np/Cholesterol	0.01	0.015	-9999.0	0.0	-0.347	1.0	1.0
PTCH1	-0.034	0.209	0.313	2.0	-0.571	105.0	107.0
HHIP	0.024	0.03	0.265	7.0	-0.59	1.0	8.0