Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.061 0.204 0.314 1.0 -0.396 158.0 159.0 MAP3K8 0.009 0.045 -9999.0 0.0 -0.595 4.0 4.0 FOS -0.022 0.143 0.319 2.0 -0.457 39.0 41.0 PRKCA -0.003 0.088 0.244 1.0 -0.597 18.0 19.0 PTPN7 0.02 0.061 0.254 49.0 -9999.0 0.0 49.0 HRAS 0.023 0.013 0.265 2.0 -9999.0 0.0 2.0 PRKCB 0.005 0.08 0.258 16.0 -0.596 12.0 28.0 NRAS 0.022 0.005 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.023 0.035 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.006 0.093 -9999.0 0.0 -0.805 5.0 5.0 MAP2K1 -0.012 0.119 -9999.0 0.0 -0.511 35.0 35.0 ELK1 0.005 0.029 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.013 0.101 -9999.0 0.0 -0.504 31.0 31.0 mol:GTP -0.002 0.003 -9999.0 0.0 -0.006 278.0 278.0 MAPK1 -0.009 0.12 -9999.0 0.0 -0.458 34.0 34.0 RAF1 -0.012 0.1 -9999.0 0.0 -0.499 31.0 31.0 KRAS 0.022 0.005 -9999.0 0.0 -9999.0 0.0 0.0