Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.09 0.196 0.442 26.0 -9999.0 0.0 26.0 KIRREL -0.079 0.217 -9999.0 0.0 -0.617 16.0 16.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.09 0.197 -9999.0 0.0 -0.442 26.0 26.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.073 0.141 -9999.0 0.0 -0.397 12.0 12.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.031 0.114 -9999.0 0.0 -0.318 12.0 12.0 FYN -0.058 0.14 -9999.0 0.0 -0.376 12.0 12.0 mol:Ca2+ -0.072 0.14 -9999.0 0.0 -0.393 12.0 12.0 mol:DAG -0.073 0.141 -9999.0 0.0 -0.395 12.0 12.0 NPHS2 -0.01 0.024 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.073 0.141 -9999.0 0.0 -0.395 12.0 12.0 regulation of endocytosis -0.048 0.132 -9999.0 0.0 -0.349 12.0 12.0 Nephrin/NEPH1/podocin/Cholesterol -0.075 0.144 -9999.0 0.0 -0.328 26.0 26.0 establishment of cell polarity -0.09 0.196 -9999.0 0.0 -0.442 26.0 26.0 Nephrin/NEPH1/podocin/NCK1-2 -0.054 0.133 -9999.0 0.0 -0.568 2.0 2.0 Nephrin/NEPH1/beta Arrestin2 -0.048 0.134 -9999.0 0.0 -0.353 12.0 12.0 NPHS1 -0.056 0.162 -9999.0 0.0 -0.529 12.0 12.0 Nephrin/NEPH1/podocin -0.059 0.14 -9999.0 0.0 -0.378 12.0 12.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.073 0.141 -9999.0 0.0 -0.397 12.0 12.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.073 0.141 -9999.0 0.0 -0.397 12.0 12.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.077 0.156 -9999.0 0.0 -0.379 15.0 15.0 cytoskeleton organization -0.036 0.136 -9999.0 0.0 -0.393 8.0 8.0 Nephrin/NEPH1 -0.063 0.143 -9999.0 0.0 -0.317 26.0 26.0 Nephrin/NEPH1/ZO-1 -0.079 0.153 -9999.0 0.0 -0.427 12.0 12.0