Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.034 0.15 0.428 12.0 -9999.0 0.0 12.0 KIRREL -0.05 0.189 -9999.0 0.0 -0.486 16.0 16.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.034 0.15 -9999.0 0.0 -0.429 12.0 12.0 PLCG1 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.007 0.124 -9999.0 0.0 -0.342 11.0 11.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.021 0.092 -9999.0 0.0 -0.282 11.0 11.0 FYN -0.021 0.125 0.249 6.0 -0.321 11.0 17.0 mol:Ca2+ -0.003 0.12 -9999.0 0.0 -0.341 10.0 10.0 mol:DAG -0.002 0.121 -9999.0 0.0 -0.342 10.0 10.0 NPHS2 -0.008 0.032 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.002 0.121 -9999.0 0.0 -0.342 10.0 10.0 regulation of endocytosis -0.009 0.109 -9999.0 0.0 -0.303 11.0 11.0 Nephrin/NEPH1/podocin/Cholesterol -0.015 0.119 -9999.0 0.0 -0.34 11.0 11.0 establishment of cell polarity -0.034 0.15 -9999.0 0.0 -0.428 12.0 12.0 Nephrin/NEPH1/podocin/NCK1-2 -0.004 0.118 -9999.0 0.0 -0.316 11.0 11.0 Nephrin/NEPH1/beta Arrestin2 -0.008 0.111 -9999.0 0.0 -0.306 11.0 11.0 NPHS1 -0.02 0.071 -9999.0 0.0 -0.239 8.0 8.0 Nephrin/NEPH1/podocin -0.013 0.113 -9999.0 0.0 -0.322 11.0 11.0 TJP1 0.027 0.003 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.021 0.012 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.001 0.122 -9999.0 0.0 -0.344 10.0 10.0 CD2AP 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.006 0.125 -9999.0 0.0 -0.342 11.0 11.0 GRB2 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.029 0.131 0.267 5.0 -0.321 13.0 18.0 cytoskeleton organization -0.029 0.112 0.201 3.0 -0.336 11.0 14.0 Nephrin/NEPH1 -0.02 0.108 -9999.0 0.0 -0.321 11.0 11.0 Nephrin/NEPH1/ZO-1 -0.012 0.129 -9999.0 0.0 -0.364 11.0 11.0