Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.058 0.203 0.615 28.0 -9999.0 0.0 28.0 KIRREL 0.002 0.056 -9999.0 0.0 -0.799 1.0 1.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.058 0.203 -9999.0 0.0 -0.616 28.0 28.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.035 0.166 -9999.0 0.0 -0.477 29.0 29.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.009 0.1 -9999.0 0.0 -0.549 1.0 1.0 FYN -0.036 0.148 -9999.0 0.0 -0.428 29.0 29.0 mol:Ca2+ -0.035 0.164 -9999.0 0.0 -0.472 29.0 29.0 mol:DAG -0.035 0.165 -9999.0 0.0 -0.474 29.0 29.0 NPHS2 -0.008 0.079 -9999.0 0.0 -0.837 2.0 2.0 mol:IP3 -0.035 0.165 -9999.0 0.0 -0.474 29.0 29.0 regulation of endocytosis -0.024 0.141 -9999.0 0.0 -0.4 29.0 29.0 Nephrin/NEPH1/podocin/Cholesterol -0.043 0.165 -9999.0 0.0 -0.483 29.0 29.0 establishment of cell polarity -0.058 0.203 -9999.0 0.0 -0.615 28.0 28.0 Nephrin/NEPH1/podocin/NCK1-2 -0.024 0.155 -9999.0 0.0 -0.435 29.0 29.0 Nephrin/NEPH1/beta Arrestin2 -0.024 0.144 -9999.0 0.0 -0.405 29.0 29.0 NPHS1 -0.079 0.256 -9999.0 0.0 -0.803 27.0 27.0 Nephrin/NEPH1/podocin -0.034 0.149 -9999.0 0.0 -0.43 29.0 29.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.035 0.166 -9999.0 0.0 -0.477 29.0 29.0 CD2AP 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.035 0.166 -9999.0 0.0 -0.477 29.0 29.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.036 0.153 -9999.0 0.0 -0.439 29.0 29.0 cytoskeleton organization -0.015 0.131 -9999.0 0.0 -0.743 1.0 1.0 Nephrin/NEPH1 -0.041 0.152 -9999.0 0.0 -0.46 28.0 28.0 Nephrin/NEPH1/ZO-1 -0.038 0.17 -9999.0 0.0 -0.505 28.0 28.0