Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.03 0.13 0.423 15.0 -9999.0 0.0 15.0 KIRREL -0.045 0.176 -9999.0 0.0 -0.576 15.0 15.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.03 0.13 -9999.0 0.0 -0.423 15.0 15.0 PLCG1 0.009 0.048 -9999.0 0.0 -0.587 1.0 1.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.021 0.097 -9999.0 0.0 -0.316 13.0 13.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.001 0.085 -9999.0 0.0 -0.27 13.0 13.0 FYN -0.015 0.093 -9999.0 0.0 -0.302 13.0 13.0 mol:Ca2+ -0.033 0.102 -9999.0 0.0 -0.339 13.0 13.0 mol:DAG -0.033 0.102 -9999.0 0.0 -0.341 13.0 13.0 NPHS2 -0.005 0.043 -9999.0 0.0 -0.484 1.0 1.0 mol:IP3 -0.033 0.102 -9999.0 0.0 -0.341 13.0 13.0 regulation of endocytosis -0.006 0.088 -9999.0 0.0 -0.278 13.0 13.0 Nephrin/NEPH1/podocin/Cholesterol -0.021 0.099 -9999.0 0.0 -0.308 16.0 16.0 establishment of cell polarity -0.03 0.13 -9999.0 0.0 -0.423 15.0 15.0 Nephrin/NEPH1/podocin/NCK1-2 -0.003 0.091 -9999.0 0.0 -0.282 13.0 13.0 Nephrin/NEPH1/beta Arrestin2 -0.005 0.089 -9999.0 0.0 -0.281 13.0 13.0 NPHS1 0.0 0.017 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin -0.015 0.093 -9999.0 0.0 -0.303 13.0 13.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.023 0.107 -9999.0 0.0 -0.342 13.0 13.0 CD2AP 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.021 0.097 -9999.0 0.0 -0.316 13.0 13.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.038 0.13 -9999.0 0.0 -0.317 25.0 25.0 cytoskeleton organization 0.001 0.098 -9999.0 0.0 -0.306 13.0 13.0 Nephrin/NEPH1 -0.02 0.093 -9999.0 0.0 -0.3 15.0 15.0 Nephrin/NEPH1/ZO-1 -0.03 0.1 -9999.0 0.0 -0.331 15.0 15.0