Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.013 0.098 0.298 13.0 -9999.0 0.0 13.0 KIRREL -0.004 0.126 -9999.0 0.0 -0.409 13.0 13.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.013 0.098 -9999.0 0.0 -0.299 13.0 13.0 PLCG1 0.027 0.037 -9999.0 0.0 -0.4 1.0 1.0 ARRB2 0.032 0.005 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.023 0.015 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.042 0.088 -9999.0 0.0 -0.225 13.0 13.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.0 0.061 -9999.0 0.0 -0.217 9.0 9.0 FYN -0.019 0.075 0.153 10.0 -0.214 13.0 23.0 mol:Ca2+ 0.037 0.093 -9999.0 0.0 -0.239 13.0 13.0 mol:DAG 0.038 0.094 -9999.0 0.0 -0.24 13.0 13.0 NPHS2 0.019 0.027 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.038 0.094 -9999.0 0.0 -0.24 13.0 13.0 regulation of endocytosis 0.029 0.077 -9999.0 0.0 -0.205 13.0 13.0 Nephrin/NEPH1/podocin/Cholesterol 0.028 0.081 -9999.0 0.0 -0.22 13.0 13.0 establishment of cell polarity 0.013 0.098 -9999.0 0.0 -0.298 13.0 13.0 Nephrin/NEPH1/podocin/NCK1-2 0.059 0.09 -9999.0 0.0 -0.209 13.0 13.0 Nephrin/NEPH1/beta Arrestin2 0.031 0.079 -9999.0 0.0 -0.207 13.0 13.0 NPHS1 0.02 0.027 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin 0.026 0.077 -9999.0 0.0 -0.215 13.0 13.0 TJP1 0.032 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.032 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.033 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.04 0.094 -9999.0 0.0 -0.241 13.0 13.0 CD2AP 0.032 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.047 0.086 -9999.0 0.0 -0.225 12.0 12.0 GRB2 0.032 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.034 0.093 0.158 11.0 -0.22 22.0 33.0 cytoskeleton organization -0.015 0.062 0.197 1.0 -0.242 8.0 9.0 Nephrin/NEPH1 0.015 0.069 -9999.0 0.0 -0.203 13.0 13.0 Nephrin/NEPH1/ZO-1 0.031 0.086 -9999.0 0.0 -0.238 13.0 13.0