Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.02 0.071 0.304 1.0 -0.242 13.0 14.0 MAP3K8 0.018 0.026 -9999.0 0.0 -0.063 37.0 37.0 FOS 0.011 0.062 0.252 2.0 -0.238 13.0 15.0 PRKCA 0.031 0.004 -9999.0 0.0 0.0 6.0 6.0 PTPN7 0.03 0.008 0.066 1.0 -0.044 2.0 3.0 HRAS 0.031 0.007 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.001 0.002 0.018 1.0 -0.003 121.0 122.0 NRAS 0.008 0.041 -9999.0 0.0 -0.063 125.0 125.0 RAS family/GTP 0.03 0.046 -9999.0 0.0 -0.044 119.0 119.0 MAPK3 0.026 0.032 -9999.0 0.0 -0.356 2.0 2.0 MAP2K1 -0.003 0.026 0.123 1.0 -0.159 3.0 4.0 ELK1 0.031 0.005 -9999.0 0.0 -0.022 2.0 2.0 BRAF 0.004 0.017 0.098 1.0 -0.232 2.0 3.0 mol:GTP -0.0 0.0 0.003 1.0 -0.001 124.0 125.0 MAPK1 0.0 0.101 -9999.0 0.0 -0.354 36.0 36.0 RAF1 0.006 0.016 0.098 1.0 -0.221 2.0 3.0 KRAS 0.03 0.008 -9999.0 0.0 -9999.0 0.0 0.0