Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.012 0.164 -9999.0 0.0 -0.476 16.0 16.0 MAP3K8 0.027 0.008 -9999.0 0.0 -9999.0 0.0 0.0 FOS -0.004 0.118 -9999.0 0.0 -0.502 7.0 7.0 PRKCA 0.02 0.03 -9999.0 0.0 -0.386 1.0 1.0 PTPN7 -0.001 0.094 -9999.0 0.0 -0.399 15.0 15.0 HRAS 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB 0.011 0.068 -9999.0 0.0 -0.41 7.0 7.0 NRAS 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.043 0.024 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.009 0.093 -9999.0 0.0 -0.624 4.0 4.0 MAP2K1 0.012 0.067 -9999.0 0.0 -0.484 2.0 2.0 ELK1 0.019 0.023 -9999.0 0.0 -9999.0 0.0 0.0 BRAF 0.011 0.042 -9999.0 0.0 -0.425 1.0 1.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.005 48.0 48.0 MAPK1 0.009 0.092 -9999.0 0.0 -0.708 3.0 3.0 RAF1 0.007 0.061 -9999.0 0.0 -0.315 6.0 6.0 KRAS 0.026 0.008 -9999.0 0.0 -9999.0 0.0 0.0