Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.643 0.271 0.741 57.0 -9999.0 0.0 57.0 KIRREL -0.105 0.185 -9999.0 0.0 -0.94 3.0 3.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.644 0.272 -9999.0 0.0 -0.743 57.0 57.0 PLCG1 0.008 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 -0.009 0.053 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.008 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.663 0.348 -9999.0 0.0 -0.741 59.0 59.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.505 0.287 -9999.0 0.0 -0.567 59.0 59.0 FYN -0.625 0.331 -9999.0 0.0 -0.7 59.0 59.0 mol:Ca2+ -0.651 0.337 -9999.0 0.0 -0.728 59.0 59.0 mol:DAG -0.657 0.342 -9999.0 0.0 -0.735 59.0 59.0 NPHS2 -0.397 0.427 -9999.0 0.0 -0.943 25.0 25.0 mol:IP3 -0.657 0.342 -9999.0 0.0 -0.735 59.0 59.0 regulation of endocytosis -0.595 0.309 -9999.0 0.0 -0.664 59.0 59.0 Nephrin/NEPH1/podocin/Cholesterol -0.667 0.349 -9999.0 0.0 -0.747 59.0 59.0 establishment of cell polarity -0.643 0.271 -9999.0 0.0 -0.741 57.0 57.0 Nephrin/NEPH1/podocin/NCK1-2 -0.619 0.332 -9999.0 0.0 -0.692 59.0 59.0 Nephrin/NEPH1/beta Arrestin2 -0.608 0.321 -9999.0 0.0 -0.679 59.0 59.0 NPHS1 -0.769 0.319 -9999.0 0.0 -0.903 56.0 56.0 Nephrin/NEPH1/podocin -0.632 0.334 -9999.0 0.0 -0.707 59.0 59.0 TJP1 0.008 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.008 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.008 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.663 0.348 -9999.0 0.0 -0.741 59.0 59.0 CD2AP 0.008 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.663 0.348 -9999.0 0.0 -0.741 59.0 59.0 GRB2 0.008 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.618 0.331 -9999.0 0.0 -0.693 59.0 59.0 cytoskeleton organization -0.666 0.354 -9999.0 0.0 -0.748 59.0 59.0 Nephrin/NEPH1 -0.496 0.218 -9999.0 0.0 -0.572 57.0 57.0 Nephrin/NEPH1/ZO-1 -0.54 0.235 -9999.0 0.0 -0.623 57.0 57.0